VA Office of Research and Development

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, VA Office of Research and Development sits in the top decile of US sponsors by registered trial count (#11 of 15,742 sponsors by registered trial count).

1,668 total trials 291 currently recruiting 1108 completed early-phase tilt top decile by trial count

VA Office of Research and Development: 1,668 sponsored US clinical trials, 291 recruiting.

VA Office of Research and Development sponsors 1,668 registered US clinical trials on ClinicalTrials.gov, 291 of them currently recruiting, and 1,108 completed. 124 of these trials are in Phase 3-4 (later-stage) and 236 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Post Traumatic Stress Disorder, with 45 trials.

Top-decile sponsor footprint

VA Office of Research and Development ranks in the top decile of sponsors by registered trial count (#11 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 75/100

1,108 of 1,180 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (93.9%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,668 total, page 15 of 34

COMPLETED

Observational Study of Convalescent Plasma for Treatment of Veterans With COVID-19

NCT04545047

COMPLETED NA

Health Coaching for Chronic Multisymptom Illness

NCT04157101

COMPLETED

Beige Fat, Energy, and the Natriuretic Peptide System

NCT04357964

COMPLETED NA

Remote Access to Urinary Incontinence Treatment for Women Veterans

NCT04237753

TERMINATED NA

Grasping Function After Spinal Cord Injury

NCT03447509

COMPLETED NA

Functional Interval Training for Veterans Exercising Through Telehealth.

NCT04103593

COMPLETED NA

Pilot Study Testing a Web-Based Moral Elevation Intervention for Veterans With PTSD and Moral Injury

NCT03906240

COMPLETED NA

Randomized Controlled Trial of CES for Fibromyalgia

NCT04115033

COMPLETED NA

Million Veteran Program Return of Actionable Results

NCT04178122

COMPLETED Phase 2

Apnea and Insomnia Relief Study

NCT04007796

COMPLETED NA

Heated Vest for Persons With Spinal Cord Injury

NCT03662308

TERMINATED Early Phase 1

AIH for Spinal Cord Repair

NCT03780829

COMPLETED NA

Feasibility and Acceptability of Using Low-Gain Hearing Aids for Bothersome Tinnitus

NCT03904264

COMPLETED NA

Cognitive Rehab for Parkinson's

NCT03836963

TERMINATED Phase 2

A Pharmaco-imaging Approach to Predicting Social Functioning and Clinical Responses to Oxytocin Administration in Schizophrenia

NCT03900754

COMPLETED NA

Uphill Walking as Exercise for COPD Patients

NCT04026529

COMPLETED NA

Mindfulness-Based Stress Reduction to Improve Neuropsychological Functioning in Acquired Brain Injury

NCT03969563

COMPLETED NA

Effects of tDCS Paired With Cognitive Training on Brain Networks Associated With Alcohol Use Disorder in Veterans

NCT04574167

COMPLETED NA

Mindfulness Based Stress Reduction for Parkinson's Disease: A Longitudinal Study

NCT03998462

TERMINATED NA

Low Dose Niacin (Vitamin B3) for Parkinson's Disease

NCT03808961

COMPLETED NA

Using Behavioral Economics to Enhance Appointment Reminders and Reduce Missed Visits

NCT03850431

COMPLETED NA

Veterans Achieving Weight Loss and Optimizing Resilience-Using Protein

NCT03835416

COMPLETED NA

Understanding Trauma Nightmares Using In-Home Measurement

NCT03974503

COMPLETED Phase 4

Effectiveness of Combining Behavioral and Pharmacologic Therapy for Complex Insomnia in Veterans With PTSD

NCT03937713

COMPLETED NA

Somatosensory Tinnitus Study

NCT03802513

COMPLETED NA

Improving Quality of Life for Veterans With Stroke and Psychological Distress

NCT03645759

COMPLETED Phase 4

Mobile Evidence-Based Smoking Cessation for Veterans Living With HIV (MESH)

NCT04135937

COMPLETED NA

Neurocognitive Factors in Substance Use Treatment Response: The Ways of Rewarding Abstinence Project

NCT03799341

COMPLETED NA

Identifying Effective Treatment for Veterans Unwilling to Quit Smoking

NCT04061720

COMPLETED Phase 4

CPT-SMART for Treatment of PTSD and Cigarette Smoking

NCT03978442

COMPLETED NA

Combined TMS and Brief Cognitive Behavioral Therapy to Reduce Suicide

NCT03952468

COMPLETED NA

Remotely Supervised tDCS for Persistent Post-traumatic Headache

NCT04012853

COMPLETED NA

Chronic Electrical Stimulation to Reduce Bladder Hyperreflexia

NCT03472599

COMPLETED NA

Improving Sleep in Veterans With TBI

NCT03785600

TERMINATED NA

Efficacy of a Coupler-based Fitting Approach for Experienced Users Receiving Replacement Hearing Aids

NCT03569228

TERMINATED NA

Transcranial Magnetic Stimulation (rTMS) as a Tool to Decrease Pain and Improve Functioning

NCT03821337

COMPLETED NA

Mission Reconnect-Veterans and Their Partners to Manage Pain and PTSD (MR)

NCT03593772

COMPLETED NA

Drug Reduction in Older Patients: The DROP Trial

NCT03722017

COMPLETED NA

Tele-Self CBTI Trial

NCT03727438

COMPLETED NA

Consortium to Disseminate and Understand Implementation of Opioid Use Disorder Treatment

NCT04178551

COMPLETED NA

Compassion Meditation for Older Adults

NCT03964246

COMPLETED NA

rTMS in Alleviating Pain and Co-Morbid Symptoms in Gulf War Veterans Illness (GWVI)

NCT04046536

COMPLETED Phase 2

Cannabidiol and Prolonged Exposure

NCT03518801

COMPLETED NA

Highly Challenging Balance Program to Reduce Fall Rate in PD

NCT03972969

COMPLETED NA

Reducing Potentially Inappropriate Medication Prescribing for Older Patients in the ED

NCT04004936

COMPLETED NA

Veteran Support and Resources for Diabetes

NCT04041375

COMPLETED NA

Enhanced Problem-Solving Training

NCT03759223

TERMINATED NA

Pneumatic Technology for Powered Mobility Devices

NCT03898362

COMPLETED NA

Effect of Constraint-Induced Gaming Therapy in an Acute Care Setting

NCT03578536

COMPLETED

Understanding Prosthetic Needs and Outcomes in Women Veterans With Amputation

NCT03733054

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Phase Distribution

PhaseTrial count
Phase 1 89
Phase 2 147
Phase 3 55
Phase 4 69

What is open in the VA Office of Research and Development pipeline

291 recruiting of 1,668 indexed (17% open); 1,108 completed (66%).

Phase mix: 124 late (III/IV) vs 236 early (I/II) (early-phase heavy).

Top condition: Post Traumatic Stress Disorder (45 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

VA Office of Research and Development: open-pipeline peers nationwide

Peers matched on 1,668 registered trials and 17% open enrollment, not the therapeutic-area sidebar.

VA Office of Research and Development sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,000 10%12%14%16%18% Total trials Recruiting share VA Office of Research and DevelopmentUniversity of California, San FranciscoDuke UniversityStanford UniversityWashington University School of MedicineUniversity of South FloridaImmunityBioOld Dominion UniversityTexas Tech University
VA Office of Research and Development sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

VA Office of Research and Development sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,668 trials (± recruiting share)

Sponsors near 17% open enrollment (± trial volume)

What to do with this VA Office of Research and Development page

1,668 registered trials is a research-attention snapshot, not an endorsement of VA Office of Research and Development or any single study.

  • 291 of VA Office of Research and Development's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Post Traumatic Stress Disorder is the condition VA Office of Research and Development studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Post Traumatic Stress Disorder trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. VA Office of Research and Development pipeline card: 1,668 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.