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NCT04539275 · ClinicalTrials.gov registry record · Phase 3
VA CoronavirUs Research and Efficacy Studies-1
A Phase 3 study, sponsored by VA Office of Research and Development.
- Terminated
- Registry status
- Phase 3
- Development phase
- 75
- Enrollment target
NCT04539275: Clinical Trial Phase 3 study, sponsored by VA Office of Research and Development.
NCT04539275 is a Phase 3 study that was terminated before completion, run by VA Office of Research and Development. The registered enrollment target is 75 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04539275, a Phase 3 study, was terminated before completion, sponsored by VA Office of Research and Development.
- TERMINATED
- Registry status
- Phase 3
- Development phase
- 75 participants
- Enrollment target
Study Summary
The purpose of this study is to determine if treatment with convalescent plasma improves the clinical outcomes of Veterans who are hospitalized and require supplemental oxygen due to COVID-19.
Primary Outcome
Respiratory failure is defined as requiring mechanical ventilation, with or without endotracheal intubations, or extra-corporeal membrane oxygenation.
Interventions
- DRUG Convalescent Plasma
- OTHER Masked Saline Placebo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2020-11-16 |
| Est. Completion | 2021-09-30 |
| Phase | Phase 3 |
Why NCT04539275 stopped before completion
NCT04539275 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 75 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (90% lower).
The record links to 0 conditions, and to 2 interventions - of which Convalescent Plasma is the first listed.
NCT04539275 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04539275 about?
NCT04539275 is a clinical study titled "VA CoronavirUs Research and Efficacy Studies-1". The purpose of this study is to determine if treatment with convalescent plasma improves the clinical outcomes of Veterans who are hospitalized and require supplemental oxygen due to COVID-19.
What is the current status of trial NCT04539275?
This trial is currently terminated. It is a Phase 3 study. The enrollment target is 75 participants. The study started on 2020-11-16. Estimated completion is 2021-09-30.
What interventions are being tested in trial NCT04539275?
The interventions under investigation include: Convalescent Plasma (DRUG), Masked Saline Placebo (OTHER).
Who is sponsoring clinical trial NCT04539275?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04539275's enrollment target sits among peer trials
75 1773rd of 2000 higher than 221 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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