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NCT04274218 · ClinicalTrials.gov registry record · NA
Upper Limb Loss Perturbation Response
A NA study of Amputation, sponsored by VA Office of Research and Development.
- Completed
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT04274218: Completed NA study of Amputation, sponsored by VA Office of Research and Development.
NCT04274218 is a NA study of Amputation that has completed, run by VA Office of Research and Development. The registered enrollment target is 20 participants, below the 133-participant average among 65 other Amputation trials with a reported enrollment target (85% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04274218, a NA study of Amputation, has completed, sponsored by VA Office of Research and Development.
- COMPLETED
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
Recent investigations have suggested that persons with upper limb loss experience a high prevalence of falls with a quarter of reported falls resulting from a trip. Moreover, studies indicate that missing part of an arm may negatively impact balance and that use of a prosthesis exacerbates this problem. While the investigators are beginning to understand the effects of upper limb loss on balance, the understanding of how Veterans with upper limb loss respond to walking disturbances is incomplete. Therefore, the aims of this study are to observe the effects of upper limb loss and wearing a prosthesis on the preparation and recovery of Veterans who trip during walking. The investigators plan to use unique treadmill technology to deliver controlled, yet unexpected, perturbations to Veterans with upper limb loss and non-amputee controls, and assess walking stability through body dynamics. Results from this study will help us understand why Veterans with upper limb loss fall as a critical first step to addressing this problem through balance-targeted interventions that are integrated into patient care.
Primary Outcome
Whole-body angular momentum is the momentum of all limb segments about the Body Center of Mass (BCoM) summed. Whole-body angular momentum is estimated in the sagittal plane, which is the plane of walking progression, and the range of this value is normalized to a person's body mass, height, and walking speed. Whole body angular momentum is minimized by the central nervous system to facilitate postural control. For this study, whole body angular momentum range was averaged across the 12 perturbat
Conditions Studied
Interventions
- OTHER Perturbation
Study Locations (1)
Illinois
- Jesse Brown VA Medical Center, Chicago, IL - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2020-12-11 |
| Est. Completion | 2022-06-30 |
| Phase | NA |
What the finished NCT04274218 record still lists
NCT04274218 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 133-participant average among 65 other Amputation trials with a reported enrollment target (85% lower).
The record links to 1 condition, with Amputation appearing as the primary indexed condition, and to 1 intervention - of which Perturbation is the first listed.
NCT04274218 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT04274218 about?
NCT04274218 is a clinical study titled "Upper Limb Loss Perturbation Response". Recent investigations have suggested that persons with upper limb loss experience a high prevalence of falls with a quarter of reported falls resulting from a trip. Moreover, studies indicate that missing part of an arm may negatively impact balance and that use of a prosthesis exacerbates this prob...
What is the current status of trial NCT04274218?
This trial is currently completed. It is a NA study. The enrollment target is 20 participants. The study started on 2020-12-11. Estimated completion is 2022-06-30.
What conditions does trial NCT04274218 study?
This clinical trial studies the following conditions: Amputation.
What interventions are being tested in trial NCT04274218?
The interventions under investigation include: Perturbation (OTHER).
Who is sponsoring clinical trial NCT04274218?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04274218 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Amputation
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04274218's enrollment target sits among peer trials
20 33rd of 65 higher than 25 of 65 other Amputation trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Amputation trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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