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NCT04207346 · ClinicalTrials.gov registry record · NA

Transcranial Magnetic Stimulation to Improve Functioning in Veterans With PTSD

A NA study, sponsored by VA Office of Research and Development.

Completed
Registry status
NA
Development phase
59
Enrollment target

NCT04207346: Completed NA study, sponsored by VA Office of Research and Development.

NCT04207346 is a NA study that has completed, run by VA Office of Research and Development. The registered enrollment target is 59 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT04207346, a NA study, has completed, sponsored by VA Office of Research and Development.

COMPLETED
Registry status
NA
Development phase
59 participants
Enrollment target

Study Summary

Posttraumatic Stress Disorder (PTSD) is a common and serious condition affecting many Veterans. There are effective treatments for PTSD, but additional treatments are needed in order to better serve Veterans suffering from PTSD. Transcranial magnetic stimulation is one such promising treatment. It involves use of powerful magnet to stimulate the specific brain regions in Veterans with PTSD. Transcranial magnetic stimulation has been shown effective in treating depression, but currently it is unclear if it is an effective treatment for PTSD. This is a randomized clinical trial enrolling 91 Veterans with PTSD comparing the effectiveness of transcranial magnetic stimulation treatment and sham transcranial magnetic stimulation in treating PTSD. The hypothesis is that those who receive transcranial magnetic stimulation will experience improved functioning.

Primary Outcome

The Clinician-administered scale of PTSD symptoms (CAPS) queries the frequency and intensity of symptoms of PTSD. The score ranges from 0-80 with a higher score indicating worse symptoms. It is considered the gold standard for diagnosis and symptoms assessment in PTSD clinical studies.

Interventions

  • DEVICE Sham TMS
  • DEVICE TMS 1 hz

Trial Details

FieldValue
Enrollment Target 59 participants
Start Date 2020-12-01
Est. Completion 2025-09-30
Phase NA
VA Office of Research and Development

1,668 total trials

What the finished NCT04207346 record still lists

NCT04207346 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 59 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).

The record links to 0 conditions, and to 2 interventions - of which Sham TMS is the first listed.

NCT04207346 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04207346 about?

NCT04207346 is a clinical study titled "Transcranial Magnetic Stimulation to Improve Functioning in Veterans With PTSD". Posttraumatic Stress Disorder (PTSD) is a common and serious condition affecting many Veterans. There are effective treatments for PTSD, but additional treatments are needed in order to better serve Veterans suffering from PTSD. Transcranial magnetic stimulation is one such promising treatment. It i...

What is the current status of trial NCT04207346?

This trial is currently completed. It is a NA study. The enrollment target is 59 participants. The study started on 2020-12-01. Estimated completion is 2025-09-30.

What interventions are being tested in trial NCT04207346?

The interventions under investigation include: Sham TMS (DEVICE), TMS 1 hz (DEVICE).

Who is sponsoring clinical trial NCT04207346?

This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04207346's enrollment target sits among peer trials

59 1256th of 2000 higher than 745 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04207346, the US trial registry maintained by the National Library of Medicine. NCT04207346 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.