VA Office of Research and Development

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, VA Office of Research and Development sits in the top decile of US sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count).

1,668 total trials 291 currently recruiting 1108 completed early-phase tilt top decile by trial count

VA Office of Research and Development: 1,668 sponsored US clinical trials, 291 recruiting.

VA Office of Research and Development sponsors 1,668 registered US clinical trials on ClinicalTrials.gov, 291 of them currently recruiting, and 1,108 completed. 124 of these trials are in Phase 3-4 (later-stage) and 236 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is PTSD, with 28 trials.

Top-decile sponsor footprint

VA Office of Research and Development ranks in the top decile of sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

1,668 total, page 13 of 34

COMPLETED NA

sTMS for Substance Use-disordered Veterans

NCT04336293

COMPLETED NA

Brief Anxiety Skills Training Intervention for Veterans in Primary Care

NCT04829240

COMPLETED NA

Effect of Myofunctional Therapy on OSA

NCT04608552

COMPLETED NA

Participatory System Dynamics vs Usual Quality Improvement: Staff Use of Simulation as an Effective, Scalable and Affordable Way to Improve Timely Mental Health Care?

NCT04208217

TERMINATED Phase 1

Induction of Sensecence Using Dexamethasone to Re-sensitize NSCLC to Anti-PD1 Therapy

NCT04037462

COMPLETED NA

Feasibility of a Tele-game-based Exercise (Tele-exergame) Program to Prevent Deconditioning in Hospitalized COVID-19 Patients

NCT04743401

COMPLETED NA

VA Video Connect in HIV Care

NCT04055207

COMPLETED NA

An RCT of a Telemedicine Intervention for Hypokinetic Dysarthria in PD

NCT04617496

COMPLETED NA

Blood Flow Restriction Exercise for Those With SCI

NCT04889092

COMPLETED

Emergency Room Firearm and Medication Safety Intervention

NCT04797221

COMPLETED NA

MISSION-CJ for Justice-Involved Homeless Veterans

NCT04523337

COMPLETED NA

Corneal Nerves Function and Structure

NCT04222660

COMPLETED NA

Effectiveness and Implementation of eScreening in Post 9/11 Transition Programs

NCT04506164

COMPLETED NA

Immersive Virtual Reality in Stroke Pilot Study

NCT04429945

COMPLETED Phase 2

The Re-Prosper HF Study

NCT04551222

COMPLETED NA

Exercise Training to Improve PTSD Symptoms and Health in Older Veterans

NCT04199182

COMPLETED NA

Neuromodulation and Yoga for Mild Traumatic Brain Injury and Chronic Pain

NCT04517604

COMPLETED NA

Implementing a Hospital-Based Walking Program (STRIDE): Function QUERI 2.0

NCT04868656

COMPLETED NA

SmART-TBI: Supplementation With Amino Acid Rehabilitative Therapy in TBI

NCT04603443

COMPLETED

Diagnostic Potential of UCHL1 in Acute Decompensated Heart Failure

NCT04999995

COMPLETED Phase 1

Vestibulopathy as a Cause of Imbalance in Parkinson

NCT04768647

COMPLETED NA

Prehabilitation of Veterans With Exercise and Nutrition

NCT04485611

COMPLETED

Chronic Lung Disease and COVID-19: Understanding Severity, Recovery and Rehabilitation Needs

NCT04628039

COMPLETED NA

Intention Treatment for Anomia

NCT04267198

COMPLETED NA

Cognitive-based Prosthetics to Improve Grasp and Reaching After SCI

NCT04577573

COMPLETED NA

Muscle Stimulation for Physical Function During Stem Cell Transplant

NCT04364256

COMPLETED Phase 3

Diet and Exercise Plus Metformin to Treat Frailty in Obese Seniors

NCT04221750

COMPLETED NA

Peer Based Suicide Prevention

NCT04222673

COMPLETED NA

Piloting a Novel Peer Support Pain Self-Management Intervention (Project CONNECT)

NCT04229134

COMPLETED NA

MIDAS Cluster Randomized Controlled Trial of Implementation Strategies to Optimize Use of Medications in VA Clinical Settings

NCT05065502

COMPLETED NA

TelemEdiciNe-bAsed Cognitive TherapY for Migraines

NCT04613362

COMPLETED NA

LINK-HF2 - Remote Monitoring Analytics in Heart Failure

NCT04502563

COMPLETED NA

Adaptive Implementation Intervention for VA Suicide Risk Identification Strategy

NCT04243330

COMPLETED

Nasal Swab Objective and Statistical Evaluation (NOSE Study)

NCT07469670

COMPLETED NA

Yoga and Mantram for Chronic Pain and PTSD

NCT03816007

COMPLETED NA

Engaging Patients to Promote Deprescribing

NCT04294901

COMPLETED

Flares of Low Back Pain With Activity Research Study

NCT04828330

COMPLETED Phase 4

Discontinuation of Levothyroxine Therapy for Patients With Subclinical Hypothyroidism

NCT04288115

COMPLETED NA

Development/Testing of SUMMIT: a Tool to Help Patients Manage Pain While Tapering Opioids

NCT04746833

COMPLETED NA

Suicide Prevention Study of VA-BIC in the Veteran Population

NCT04446468

COMPLETED NA

Assessment and Treatment for Chronic Pain in Veterans With Serious Mental Illness

NCT04118283

COMPLETED

Assessing Pain, Patient Reported Outcomes and Complementary and Integrative Health

NCT05097521

COMPLETED NA

Neurofeedback Impact on Veterans With mTBI

NCT04195685

COMPLETED NA

Mobile Intervention for Veterans With PTSD and Anger

NCT03733028

COMPLETED NA

Increasing Help-Seeking Behavior Among Transitioning Veterans at Risk for Suicide With Online Gatekeeper Training

NCT04565951

COMPLETED Phase 2

Ketamine-enhanced Prolonged Exposure Therapy in PTSD

NCT04560660

COMPLETED Phase 1

Increasing Activity for Veterans With PTSD

NCT04383496

COMPLETED NA

Patient-Centered Reproductive Decision Support Tool for Women Veterans

NCT04584294

COMPLETED NA

Acceptance and Commitment Therapy to Improve Social Support for Veterans With PTSD

NCT04567680

COMPLETED NA

Prism Adaptation in Left Brain Stroke

NCT04387162

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Phase Distribution

PhaseTrial count
Phase 1 89
Phase 2 147
Phase 3 55
Phase 4 69

What is open in the VA Office of Research and Development pipeline

291 recruiting of 1,668 indexed (17% open); 1,108 completed (66%).

Phase mix: 124 late (III/IV) vs 236 early (I/II) (early-phase heavy).

Top condition: PTSD (28 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.