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NCT04545489 · ClinicalTrials.gov registry record · NA
A Nurse-led Intervention to Extend the Veteran HIV Treatment Cascade for Cardiovascular Disease Prevention
A NA study, sponsored by VA Office of Research and Development.
- Completed
- Registry status
- NA
- Development phase
- 305
- Enrollment target
NCT04545489: Completed NA study, sponsored by VA Office of Research and Development.
NCT04545489 is a NA study that has completed, run by VA Office of Research and Development. The registered enrollment target is 305 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (78% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04545489, a NA study, has completed, sponsored by VA Office of Research and Development.
- COMPLETED
- Registry status
- NA
- Development phase
- 305 participants
- Enrollment target
Study Summary
The VA is the largest single provider of HIV care in the US and Veterans with HIV use significantly more healthcare services and have a 1.5-2x higher risk of atherosclerotic cardiovascular disease (ASCVD) compared to uninfected Veterans. The goal is to improve BP treatment for Veterans with HIV to reduce ASCVD risk. Within a randomized controlled trial (RCT), the investigators hypothesize that the VA adapted nurse-led intervention will result in a clinically significant 6 millimeters of mercury (mmHg) reduction in systolic blood pressure (SBP) over 12 months compared to those receiving enhanced education only. The study is innovative because of the use of stakeholder-engaged design process, multi-component nurse-led intervention, and VA Video Connect (VVC) to monitor CVD risk factors. The project meets VA strategic priorities including: 1) greater choice for Veterans; 2) improve timeliness of services; 3) focus more resources more efficiently (strengthen foundational services in VA). If shown to be effective, this intervention will have substantial impact among high-risk Veterans, potentially reducing ASCVD events by more than a quarter.
Primary Outcome
Mean BP is calculated as the average of 3 BP measurements. Collected during BP outcome assessment conducted at interviews.
Interventions
- BEHAVIORAL Intervention group
- BEHAVIORAL Education control group
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 305 participants |
| Start Date | 2020-12-01 |
| Est. Completion | 2025-03-31 |
| Phase | NA |
What the finished NCT04545489 record still lists
NCT04545489 is an interventional study that assigns participants to a tested intervention. The registered 305 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (78% lower).
The record links to 0 conditions, and to 2 interventions - of which Intervention group is the first listed.
NCT04545489 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04545489 about?
NCT04545489 is a clinical study titled "A Nurse-led Intervention to Extend the Veteran HIV Treatment Cascade for Cardiovascular Disease Prevention". The VA is the largest single provider of HIV care in the US and Veterans with HIV use significantly more healthcare services and have a 1.5-2x higher risk of atherosclerotic cardiovascular disease (ASCVD) compared to uninfected Veterans. The goal is to improve BP treatment for Veterans with HIV to r...
What is the current status of trial NCT04545489?
This trial is currently completed. It is a NA study. The enrollment target is 305 participants. The study started on 2020-12-01. Estimated completion is 2025-03-31.
What interventions are being tested in trial NCT04545489?
The interventions under investigation include: Intervention group (BEHAVIORAL), Education control group (BEHAVIORAL).
Who is sponsoring clinical trial NCT04545489?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04545489's enrollment target sits among peer trials
305 327th of 2000 higher than 1,674 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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