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NCT04241250 · ClinicalTrials.gov registry record · Phase 2

Neuromodulation Techniques After SCI

A Phase 2 study of Spinal Cord Injury, sponsored by VA Office of Research and Development.

Completed
Registry status
Phase 2
Development phase
4
Enrollment target
1
Study location

NCT04241250: Completed Phase 2 study of Spinal Cord Injury, sponsored by VA Office of Research and Development.

NCT04241250 is a Phase 2 study of Spinal Cord Injury that has completed, run by VA Office of Research and Development. The registered enrollment target is 4 participants, below the 86-participant average among 99 other Spinal Cord Injury trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04241250, a Phase 2 study of Spinal Cord Injury, has completed, sponsored by VA Office of Research and Development.

COMPLETED
Registry status
Phase 2
Development phase
4 participants
Enrollment target
1
Study location

Study Summary

Spinal cord injury (SCI) leads to several health-related consequences often linked to reduced levels of physical activity. Direct stimulation of the spinal cord, either through implanted devices or surface stimulation, has been combined with intense physical therapy assisted treadmill walking to facilitate independent standing and stepping. These current methods require 3-4 highly skilled therapists and may not be feasible in all rehabilitation settings, especially when considering the growing number of SCI patients each year. Therefore, the use of robotic exoskeleton suits combined with direct stimulation of the spinal cord (requiring 1-2 therapists) may offer an alternative rehabilitation approach to overcome their limited abilities to stand and walk. Such improvements may also help to reverse or eliminate other health-related consequences associated with SCI. The pilot work will provide the preliminary evidence required to design future clinical trials for Veterans and civilians with SCI to restore overground mobility.

Primary Outcome

After fitted in the robotic exoskeleton, the participant will be asked to walk for 10-meter distance and the time and speed will be determined. Measurements were conducted over the course of 9 months.

Conditions Studied

Spinal Cord Injury

Interventions

  • DEVICE EAW+SCES (exoskelton and spinal cord epidural stimulation)
  • DEVICE EAW+TS (exoskelton and transspinal stimulation)

Study Locations (1)

Virginia

  • Hunter Holmes McGuire VA Medical Center, Richmond, VA - Richmond

Trial Details

FieldValue
Enrollment Target 4 participants
Start Date 2020-06-01
Est. Completion 2024-12-31
Phase Phase 2
VA Office of Research and Development

1,668 total trials

What the finished NCT04241250 record still lists

NCT04241250 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 86-participant average among 99 other Spinal Cord Injury trials with a reported enrollment target (95% lower).

The record links to 1 condition, with Spinal Cord Injury appearing as the primary indexed condition, and to 2 interventions - of which EAW+SCES (exoskelton and spinal cord epidural stimulation) is the first listed.

NCT04241250 reports a single indexed study location in Virginia.

Frequently Asked Questions

What is clinical trial NCT04241250 about?

NCT04241250 is a clinical study titled "Neuromodulation Techniques After SCI". Spinal cord injury (SCI) leads to several health-related consequences often linked to reduced levels of physical activity. Direct stimulation of the spinal cord, either through implanted devices or surface stimulation, has been combined with intense physical therapy assisted treadmill walking to fac...

What is the current status of trial NCT04241250?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 4 participants. The study started on 2020-06-01. Estimated completion is 2024-12-31.

What conditions does trial NCT04241250 study?

This clinical trial studies the following conditions: Spinal Cord Injury.

What interventions are being tested in trial NCT04241250?

The interventions under investigation include: EAW+SCES (exoskelton and spinal cord epidural stimulation) (DEVICE), EAW+TS (exoskelton and transspinal stimulation) (DEVICE).

Who is sponsoring clinical trial NCT04241250?

This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04241250 being conducted?

This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Spinal Cord Injury

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04241250's enrollment target sits among peer trials

4 98th of 99 higher than 2 of 99 other Spinal Cord Injury trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Spinal Cord Injury trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Related registry views

Source: ClinicalTrials.gov NCT04241250, the US trial registry maintained by the National Library of Medicine. NCT04241250 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.