University of Pennsylvania
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, University of Pennsylvania sits in the top decile of US sponsors by registered trial count (#15 of 15,742 sponsors by registered trial count).
University of Pennsylvania: 1,423 sponsored US clinical trials, 199 recruiting.
University of Pennsylvania sponsors 1,423 registered US clinical trials on ClinicalTrials.gov, 199 of them currently recruiting, and 982 completed. 130 of these trials are in Phase 3-4 (later-stage) and 339 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 17 trials.
Top-decile sponsor footprint
University of Pennsylvania ranks in the top decile of sponsors by registered trial count (#15 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
982 of 1,090 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (90.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
1,423 total, page 3 of 29
Using the EHR to Advance Genomic Medicine Across a Diverse Health System
NCT06377033
Testing LiverWatch, a Home-Based Remote-Monitoring Intervention for Advanced Liver Disease
NCT06136221
A Mechanistic Trial of the Neurobiology of Extinction Learning and Intraparietal Sulcus Stimulation
NCT06234969
Improving Care Transitions for Medicaid Insured Individuals With Co-occurring Serious Mental Illness
NCT06203509
Open Label Trial of Oral Letermovir for CMV Prophylaxis in Thoracic Transplant Recipients
NCT06066957
MicroRNAs as Biomarkers for Obstructive Sleep Apnea
NCT06189755
Text-Messaging Telehealth and Contingency Management for Opioid Use Disorder Treatment Engagement
NCT05897788
Penn Medicine Healthy Heart
NCT06062394
iCare4Me Transitions
NCT06167746
Effect of Nutritional Ketosis on Alcohol Metabolism
NCT06065657
CD33KO-HSPC Infusion Followed by CART-33 Infusion(s) for Refractory/Relapsed AML
NCT05945849
Study of Biodistribution, Metabolism, Excretion and Brain Uptake11C-M503
NCT06303921
TmPSMA-02 in mCRPC
NCT06046040
Dosing of LT4 in Older Individuals
NCT06073665
Enriched Holistic Care to Eradicate Disparities in Maternal Morbidity
NCT06245057
Feasibility of Semaglutide in Advanced Lung Disease
NCT05746039
Pregabalin Plus Lofexidine for the Outpatient Treatment of Opioid Withdrawal
NCT05995535
Transforming Hemodialysis-Related Vascular Access Education
NCT05997875
TmCD19-IL18 in CD19+ Cancers
NCT05989204
Integrating Brain, Neurocognitive, and Computational Tools in OUD
NCT06136247
CT Evaluation of Carotid Plaque Components
NCT05764772
Disentangling the Role of Depression in Hypersomnia
NCT05850676
Food Genetics Behavior Study
NCT05783765
Study of Biodistribution, Metabolism, Excretion and Brain Uptake of 11C-HY-2-15
NCT06032026
CW2IP2: Imaging and Diagnostic Assessments
NCT06083467
Guselkumab vs Golimumab in PsA TNF Inadequate Responder Patients
NCT05669833
Glaucoma Drainage Device and Endothelial Cell Loss Compare Trial
NCT05924477
Symptom Monitoring in Hemodialysis
NCT05738330
Prevention of Cardiovascular Disease and Mortality in Patients With Psoriasis or Psoriatic Arthritis
NCT05908240
Effects of the Contraceptive Implant in Women With Sickle Cell Disease
NCT05730205
Human Learning of New Structured Information Across Time and Sleep
NCT05910762
Improving the Organizational Social Context to Address Structural Racism and Discrimination
NCT06462807
Randomized Assessment of TcMS for VT Storm
NCT05599022
Cervical Ripening as an Outpatient Method Using the Foley (COMFORT)
NCT05759988
Reducing Patient Memory Recall in the Burning Mouth Patient Population
NCT05819697
Tau PET/CT Imaging in the Mismatch Prospective Cohort Study (MPC-TAU)
NCT05658913
AI-Based Fidelity Feedback to Enhance CBT
NCT05340738
Longitudinal Study for Central Nervous System Vasculitis
NCT05734404
Decoding and Modulating Affective Brain States
NCT05437705
Anti-retroviral Therapy, Medications for Opioid Use Disorder, Opioids and HIV Infection - Study 1
NCT04480554
Posterior Cingulate Cortex and Executive Control of Episodic Memory
NCT06540976
The Actuate-CBC Study
NCT05917652
Technology Enabled Strategies to Promote Treatment Adherence in Liver Transplant
NCT05260268
Multi-System Analysis of Opioid Receptor Binding
NCT05528848
PET Imaging Tau Accumulation in FTLD and Atypical Alzheimer's Using [18F]-PI-2620
NCT05456503
Characterization of Cardiac Electrophysiological Effects of Autonomic Neuromodulation
NCT05377216
LCAT (Lecithin Cholesterol Acyl Transferase) Natural History Study
NCT06217588
The Diaphragmatic Initiated Ventilatory Assist (DIVA) Trial
NCT05446272
Providing Oxygen During Intubation in the NICU Trial
NCT05451953
How Hormones and Exposure and Response Prevention (EX/RP) Affect the Brain of People With OCD
NCT05359562
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 182 |
| Phase 2 | 157 |
| Phase 3 | 43 |
| Phase 4 | 87 |
Therapeutic Areas
What is open in the University of Pennsylvania pipeline
199 recruiting of 1,423 indexed (14% open); 982 completed (69%).
Phase mix: 130 late (III/IV) vs 339 early (I/II) (early-phase heavy).
Top condition: Obesity (17 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
University of Pennsylvania: open-pipeline peers nationwide
Peers matched on 1,423 registered trials and 14% open enrollment, not the therapeutic-area sidebar.
University of Pennsylvania sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 1,423 trials (± recruiting share)
- Johns Hopkins University · 1,448 trials · 17% recruiting
- Novartis Pharmaceuticals · 1,375 trials · 8% recruiting
- Yale University · 1,492 trials · 17% recruiting
- GlaxoSmithKline · 1,345 trials · 4% recruiting
Sponsors near 14% open enrollment (± trial volume)
- Seattle Institute for Biomedical and Clinical Research · 14% recruiting · 43 trials
- University of Illinois at Urbana-Champaign · 14% recruiting · 129 trials
- Johns Hopkins Bloomberg School of Public Health · 14% recruiting · 187 trials
- Milton S. Hershey Medical Center · 14% recruiting · 396 trials
Related
What to do with this University of Pennsylvania page
1,423 registered trials is a research-attention snapshot, not an endorsement of University of Pennsylvania or any single study.
- 199 of University of Pennsylvania's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Obesity is the condition University of Pennsylvania studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Obesity trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. University of Pennsylvania pipeline card: 1,423 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.