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NCT06046040 · ClinicalTrials.gov registry record · Phase 1
TmPSMA-02 in mCRPC
A Phase 1 study of Metastatic Castrate Resistant Prostate Cancer (mCRPC), sponsored by University of Pennsylvania.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT06046040: Recruiting Phase 1 study of Metastatic Castrate Resistant Prostate Cancer (mCRPC), sponsored by University of Pennsylvania.
NCT06046040 is a Phase 1 study of Metastatic Castrate Resistant Prostate Cancer (mCRPC) that is actively recruiting participants, run by University of Pennsylvania. The registered enrollment target is 30 participants, below the 240-participant average among 3 other Metastatic Castrate Resistant Prostate Cancer (mCRPC) trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06046040, a Phase 1 study of Metastatic Castrate Resistant Prostate Cancer (mCRPC), is actively recruiting participants, sponsored by University of Pennsylvania.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a Phase I, open-label dose finding study to assess the safety, tolerability, manufacturing feasibility, and preliminary efficacy of TmPSMA-02 CAR T cells in patients with metastatic castrate-resistant prostate cancer (mCRPC). Up to 4 total dose levels will be evaluated using a 3+3 dose escalation design.
Conditions Studied
Interventions
- DRUG TmPSMA-02 CAR T Cells
Study Locations (1)
Pennsylvania
- Abramson Cancer Center of the University of Pennsylvania - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2024-01-31 |
| Est. Completion | 2042-01-31 |
| Phase | Phase 1 |
What NCT06046040 shows while recruiting
NCT06046040 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 240-participant average among 3 other Metastatic Castrate Resistant Prostate Cancer (mCRPC) trials with a reported enrollment target (87% lower).
The record links to 1 condition, with Metastatic Castrate Resistant Prostate Cancer (mCRPC) appearing as the primary indexed condition, and to 1 intervention - of which TmPSMA-02 CAR T Cells is the first listed.
NCT06046040 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT06046040 about?
NCT06046040 is a clinical study titled "TmPSMA-02 in mCRPC". This is a Phase I, open-label dose finding study to assess the safety, tolerability, manufacturing feasibility, and preliminary efficacy of TmPSMA-02 CAR T cells in patients with metastatic castrate-resistant prostate cancer (mCRPC). Up to 4 total dose levels will be evaluated using a 3+3 dose escal...
What is the current status of trial NCT06046040?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2024-01-31. Estimated completion is 2042-01-31.
What conditions does trial NCT06046040 study?
This clinical trial studies the following conditions: Metastatic Castrate Resistant Prostate Cancer (mCRPC).
What interventions are being tested in trial NCT06046040?
The interventions under investigation include: TmPSMA-02 CAR T Cells (DRUG).
Who is sponsoring clinical trial NCT06046040?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06046040 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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