Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT05359562 · ClinicalTrials.gov registry record · NA

How Hormones and Exposure and Response Prevention (EX/RP) Affect the Brain of People With OCD

A NA study of OCD, sponsored by University of Pennsylvania.

Recruiting
Registry status
NA
Development phase
120
Enrollment target
2
Study locations

NCT05359562 is a NA study of OCD that is actively recruiting participants, run by University of Pennsylvania. The registered enrollment target is 120 participants, below the 811-participant average among 18 other OCD trials with a reported enrollment target (85% lower). The trial reports 2 study locations across 2 states.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT05359562, a NA study of OCD, is actively recruiting participants, sponsored by University of Pennsylvania.

RECRUITING
Registry status
NA
Development phase
120 participants
Enrollment target
2
Study locations

Study Summary

Studies show that hormones affect the brain's fear extinction network, which is relevant for therapy involving exposure and response prevention (EX/RP), a first-line treatment for obsessive compulsive disorder (OCD). This study will examine the effect of delivering EX/RP to women during different phases in their menstrual cycle to determine the effects of hormones on the fear extinction network and on their OCD symptoms.

Conditions Studied

OCD

Interventions

  • BEHAVIORAL Exposure & Response Prevention (EX/RP)

Study Locations (2)

New York

  • New York State Psychiatric Institute - New York

Pennsylvania

  • University of Pennsylvania - Philadelphia

Trial Details

FieldValue
Enrollment Target 120 participants
Start Date 2022-06-15
Est. Completion 2026-06
Phase NA

Sponsor

University of Pennsylvania

1,423 total trials

Interested in This Trial?

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05359562

The ClinicalTrials.gov registry entry for NCT05359562 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 120 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 811-participant average among 18 other OCD trials with a reported enrollment target (85% lower). The listed sponsor is University of Pennsylvania, which has 1,423 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with OCD appearing as the primary indexed condition, and to 1 intervention - of which Exposure & Response Prevention (EX/RP) is the first listed.

NCT05359562 reports 2 study locations spanning 2 distinct geographic areas - top geographies include New York, Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT05359562 about?

NCT05359562 is a clinical study titled "How Hormones and Exposure and Response Prevention (EX/RP) Affect the Brain of People With OCD". Studies show that hormones affect the brain's fear extinction network, which is relevant for therapy involving exposure and response prevention (EX/RP), a first-line treatment for obsessive compulsive disorder (OCD). This study will examine the effect of delivering EX/RP to women during different ph...

What is the current status of trial NCT05359562?

This trial is currently recruiting. It is a NA study. The enrollment target is 120 participants. The study started on 2022-06-15. Estimated completion is 2026-06.

What conditions does trial NCT05359562 study?

This clinical trial studies the following conditions: OCD.

What interventions are being tested in trial NCT05359562?

The interventions under investigation include: Exposure & Response Prevention (EX/RP) (BEHAVIORAL).

Who is sponsoring clinical trial NCT05359562?

This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05359562 being conducted?

This trial has 2 study locations across New York, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for OCD

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Explore more on PlainTrial

OCD

All registered trials for this condition

New York

All trials with a study site in New York

Recruiting now

Find trials open to new participants near you

Rankings

Top sponsors, conditions, and phases

Read our methodology - how this data is sourced, computed, and verified.

Related

Browse all → | Rankings →
Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.