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NCT06065657 · ClinicalTrials.gov registry record · Phase 2
Effect of Nutritional Ketosis on Alcohol Metabolism
A Phase 2 study of Alcohol Drinking and Magnetic Resonance Imaging, sponsored by University of Pennsylvania.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT06065657: Recruiting Phase 2 study of Alcohol Drinking and Magnetic Resonance Imaging, sponsored by University of Pennsylvania.
NCT06065657 is a Phase 2 study of Alcohol Drinking and Magnetic Resonance Imaging that is actively recruiting participants, run by University of Pennsylvania. The registered enrollment target is 20 participants, below the 630-participant average among 85 other Alcohol Drinking trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06065657, a Phase 2 study of Alcohol Drinking and Magnetic Resonance Imaging, is actively recruiting participants, sponsored by University of Pennsylvania.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
The research study is being conducted in health controls to better understand the effects of ketosis on brain functioning after 3 different, randomly assigned, 3-day dietary interventions and the acute effects of alcohol after consuming about 4-5 alcohol beverages. The labs visits will use magnetic resonance imaging (MRI) scans to study the brain, measuring levels of nicotinamide adenine dinucleotide (NAD), lactate, neurotransmitters glutamate, and Gamma-aminobutyric acid (GABA).
Primary Outcome
Breath alcohol concentration measured in mg/L of air. The range is .000 to .400 g/L. Change in breath alcohol concentration, pre to post alcohol consumption after 3 day diet intervention during lab day.
Conditions Studied
Interventions
- DRUG Ethanol
- DIETARY_SUPPLEMENT Ketone Supplement
- OTHER Control Diet
- OTHER Ketogenic diet
Study Locations (1)
Pennsylvania
- University of Pennsylvania Center for Studies of Addiction - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2024-02-29 |
| Est. Completion | 2027-07-01 |
| Phase | Phase 2 |
What NCT06065657 shows while recruiting
NCT06065657 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 630-participant average among 85 other Alcohol Drinking trials with a reported enrollment target (97% lower).
The record links to 5 conditions, with Alcohol Drinking appearing as the primary indexed condition, and to 4 interventions - of which Ethanol is the first listed.
NCT06065657 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT06065657 about?
NCT06065657 is a clinical study titled "Effect of Nutritional Ketosis on Alcohol Metabolism". The research study is being conducted in health controls to better understand the effects of ketosis on brain functioning after 3 different, randomly assigned, 3-day dietary interventions and the acute effects of alcohol after consuming about 4-5 alcohol beverages. The labs visits will use magnetic ...
What is the current status of trial NCT06065657?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2024-02-29. Estimated completion is 2027-07-01.
What conditions does trial NCT06065657 study?
This clinical trial studies the following conditions: Alcohol Drinking, Magnetic Resonance Imaging, Alcohol Intoxication, Ketogenic Dieting, Ketoses, Metabolic.
What interventions are being tested in trial NCT06065657?
The interventions under investigation include: Ethanol (DRUG), Ketone Supplement (DIETARY_SUPPLEMENT), Control Diet (OTHER), Ketogenic diet (OTHER).
Who is sponsoring clinical trial NCT06065657?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06065657 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Alcohol Drinking
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06065657's enrollment target sits among peer trials
20 76th of 85 higher than 6 of 85 other Alcohol Drinking trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Alcohol Drinking trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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