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NCT06462807 · ClinicalTrials.gov registry record · NA

Improving the Organizational Social Context to Address Structural Racism and Discrimination

A NA study of HIV/AIDS, sponsored by University of Pennsylvania.

Recruiting
Registry status
NA
Development phase
1,500
Enrollment target
1
Study location

NCT06462807 is a NA study of HIV/AIDS that is actively recruiting participants, run by University of Pennsylvania. The registered enrollment target is 1,500 participants, below the 33,156-participant average among 61 other HIV/AIDS trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06462807, a NA study of HIV/AIDS, is actively recruiting participants, sponsored by University of Pennsylvania.

RECRUITING
Registry status
NA
Development phase
1,500 participants
Enrollment target
1
Study location

Study Summary

Despite the widespread use of effective antiretroviral therapy (ART), the HIV epidemic continues to impact racial and ethnic minority populations disproportionately. Although Black/African American persons account for 13% of the U.S. population, they account for 41% of new HIV diagnoses and experience the lowest rates of retention in HIV care and viral suppression (VS) compared to other racial/ethnic groups. Structural racism and discrimination (SRD) likely contribute to racial disparities in HIV outcomes. Although the outpatient setting is a vitally important aspect of care provision for people living with HIV (PLWH), there are limited data on the impact of intra-organizational SRD on HIV outcomes. Longitudinal engagement in HIV care is needed for sustained VS and decreased community transmission of HIV. The organizational social context (OSC) includes organizational culture (organizational norms and values that drive quality of care), organizational climate (perception of the culture and how it impacts personal well-being), and workers' attitudes. Using a randomized controlled trial (RCT), we will implement ARC (Accessibility, Responsiveness, Continuity) to improve organizational behavior and reduce racial disparities in HIV outcomes for PLWH. ARC is an evidence-based intervention that uses three strategies (ARC principles, ARC component tools, and ARC mental models) to create OSCs that support the implementation of interventions to improve patient outcomes. Clinics will be randomized to ARC (n = 2) or standard of care (SOC; n= 2). Those assigned to ARC will address SRD occurring at the organizational level affecting care, including referral and treatment patterns for PLWH. A pre-implementation period will be followed by ARC and ARC-associated implementation strategies for 36 months and then a 12-month post-implementation period where we will continue to measure HIV outcomes in both arms. We will compare HIV outcomes, namely VS and retention in care, and interme

Conditions Studied

Interventions

  • BEHAVIORAL ARC

Study Locations (1)

Pennsylvania

  • University of Pennsylvania - Philadelphia

Trial Details

FieldValue
Enrollment Target 1,500 participants
Start Date 2023-05-31
Est. Completion 2026-12-01
Phase NA

Sponsor

University of Pennsylvania

1,423 total trials

What the Registry Record Tells You About NCT06462807

The ClinicalTrials.gov registry entry for NCT06462807 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 1,500 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 33,156-participant average among 61 other HIV/AIDS trials with a reported enrollment target (95% lower). The listed sponsor is University of Pennsylvania, which has 1,423 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with HIV/AIDS appearing as the primary indexed condition, and to 1 intervention - of which ARC is the first listed.

NCT06462807 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT06462807 about?

NCT06462807 is a clinical study titled "Improving the Organizational Social Context to Address Structural Racism and Discrimination". Despite the widespread use of effective antiretroviral therapy (ART), the HIV epidemic continues to impact racial and ethnic minority populations disproportionately. Although Black/African American persons account for 13% of the U.S. population, they account for 41% of new HIV diagnoses and experien...

What is the current status of trial NCT06462807?

This trial is currently recruiting. It is a NA study. The enrollment target is 1,500 participants. The study started on 2023-05-31. Estimated completion is 2026-12-01.

What conditions does trial NCT06462807 study?

This clinical trial studies the following conditions: HIV/AIDS.

What interventions are being tested in trial NCT06462807?

The interventions under investigation include: ARC (BEHAVIORAL).

Who is sponsoring clinical trial NCT06462807?

This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06462807 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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