University of Pennsylvania
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, University of Pennsylvania sits in the top decile of US sponsors by registered trial count (#15 of 15,751 sponsors by registered trial count).
University of Pennsylvania: 1,423 sponsored US clinical trials, 199 recruiting.
University of Pennsylvania sponsors 1,423 registered US clinical trials on ClinicalTrials.gov, 199 of them currently recruiting, and 982 completed. 130 of these trials are in Phase 3-4 (later-stage) and 339 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 17 trials.
Top-decile sponsor footprint
University of Pennsylvania ranks in the top decile of sponsors by registered trial count (#15 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Open and recent trials
1,423 total, page 2 of 29
CART-EGFR-IL13Ra2 in Newly Diagnosed GBM Following Initial Radiotherapy
NCT06973096
Induction of Labor After Cesarean Using Foley Alone vs. Concurrent Foley and Oxytocin
NCT07006896
Intravesical Treatment of Bladder Cancer at Home, Multi-modal Treatment Support
NCT07048496
Dental Implant Healing With TNF-Alpha Inhibitors
NCT06538870
Clinical and Biomarker Effects of Depot Medroxyprogesterone Acetate in Females With Sickle Cell Disease
NCT06665997
Combined Oral Contraceptive Pill and Resistance Starch
NCT06852365
MOVE-HF MOtivating Physical Activity With BehaVioral Economics in Heart Failure With Preserved Ejection Fraction
NCT06670001
Lung Injury is One of the Primary Causes of Morbidity and Mortality in Critically Ill Patients. These Patients Will be Monitored for: 1) Immune Cell Activation 2) Blood-based Biomarkers. In Vitro Models Derived From These Samples Will be Treated With Novel Agent PIP-2 to Evaluate Its Efficacy.
NCT07125079
Effects Ketone Supplement and Alcohol on Brain Metabolism
NCT06815237
Study of Biodistribution, Metabolism, Excretion and Brain Uptake 18F-JSS20-183A
NCT06932809
Rapid Outpatient Low-dose Initiation of Buprenorphine for OUD With Fentanyl Use
NCT06379984
Uterine Preservation in the Management of Placenta Accreta Spectrum Disorders
NCT06512181
Doula Model of Care
NCT06915259
Philly CEAL- DECIDE+ Adaptation
NCT06732102
Randomized Clinical Trial of TUNE In 3.0: A Social/Emotional Program for Adults With Autism Spectrum Disorder
NCT06859918
Army-SPRING Army-Suicide Prevention Research
NCT06547008
Antidepressant Adherence for Depressed Adults in Primary Care
NCT06496646
Healing at Home 2.0 - Enhanced Chat Tool for Lowering Postpartum Depression
NCT06877104
Videos to Aid Decision Making for Fibroid Treatment
NCT07072364
Traumatic Hemothorax Drainage and Daily Lavage: Pilot Study
NCT06937450
Transitional Housing and HIV Health
NCT06829394
Teaching Health Resilience in a Hospital Setting: A Peer-led Intervention
NCT06843213
OsciPulse D-dimer Pilot Trial
NCT06477016
Transcranial Magnetic Stimulation + Language Therapy to Treat Mild Aphasia
NCT06842745
Communication Strategies to Increase HPV Vaccination Intention
NCT06784960
Flu Infection at UPHS
NCT06807840
Remote Sputum Collection in Cystic Fibrosis
NCT06950892
Topical Anti-Androgens in Pilonidal Sinus Disease
NCT06286397
Variability in Analgesic Response to Ibuprofen
NCT06539741
Sodium Glucose Co-transporter (SGLT) Inhibitors in Nonobstructive Hypertrophic Cardiomyopathy
NCT06433050
Nasal vs Oral Breathing in Drug Induced Sleep vs Natural Sleep
NCT06789770
Diagnostic Utility of SGLT1/2 Inhibition to Facilitate Myocardial Glucose Suppression
NCT06510894
Next-Generation Photon-Counting CT Technology: Development and Clinical Evaluation
NCT06691659
Characterization and Natural History of Williams Syndrome and Other Chromosome 7q11.23 Variants
NCT06930417
Supporting Evidence-based Responses to Emotional Needs in Emphysema
NCT06600126
Mechanistic Clinical Trial of Colchicine in Patients With Peripheral Artery Disease
NCT06212271
Mechanical Insufflation in the Philadelphia Amyotrophic Lateral Sclerosis Cohort (MI-PALS) Study
NCT06119087
Postpartum Care in the NICU (PeliCaN) Transitions
NCT06521398
Letrozole and Misoprostol for Early Pregnancy Loss Management
NCT06452719
PMT for MDRO Decolonization
NCT05632315
Evaluating a Strategy to Improve Pre-Anesthesia Care Discussions (My Anesthesia Choice-Hip Fracture)
NCT06438640
Home-Based Exercise Program Using Mobile Technology After Left Ventricular Assist Device Implantation
NCT06291922
TumorGlow Intraoperative Molecular Imaging (IMI)
NCT04723810
Evaluating the Relationship Between Skin Color and Pulse Oximeter Accuracy in Children
NCT06529575
Transcranial Magnetic Stimulation + Language Therapy to Treat Subacute Aphasia
NCT06968663
Evaluation of Periapical Healing Following Endodontic Microsurgery With Leukocyte and Platelet Rich Fibrin (L-PRF)
NCT06545084
tACS to Enhance Language Abilities
NCT06092814
Sildenafil for Microvasculopathy in Chronic TBI
NCT05782244
An Intervention Mapping Approach to Closing the Gap in Maternal OUD and Infant NAS Care (SUPPORT)
NCT06576323
APPLE: Aspirin to Prevent Pregnancy Loss and Preeclampsia
NCT06408181
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 182 |
| Phase 2 | 157 |
| Phase 3 | 43 |
| Phase 4 | 87 |
Therapeutic Areas
What is open in the University of Pennsylvania pipeline
199 recruiting of 1,423 indexed (14% open); 982 completed (69%).
Phase mix: 130 late (III/IV) vs 339 early (I/II) (early-phase heavy).
Top condition: Obesity (17 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.