Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Alcoholism: early-phase trial registry
11 of 67 indexed Alcoholism trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #208 of 28,707 conditions by registered trial count.
67 US clinical trials · 11 currently recruiting · #208 of 28,707 conditions by registered trial count
Alcoholism: 67 US clinical trials tracked, 11 recruiting.
Alcoholism is the subject of 67 registered US clinical trials on ClinicalTrials.gov, 11 of them currently open to new participants. 14 are in Phase 3-4 (later-stage) and 26 in Phase 1-2 (earlier-stage). The most active sponsor is National Institute on Alcohol Abuse and Alcoholism (NIAAA), running 11 of these trials.
Enrollment posture brief
Registry condition alcoholism
OPEN 11 | RECR 16% | LATE 14 | EARLY 26 | RANK #208 | SPON 11
Volume-matched condition peers
Nearest open-share peer: Stage IVA Lung Cancer AJCC v8 (16% recruiting · 37 trials)
Alcoholism lists 11 open slots (16% of 67 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Alcoholism on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Alcoholism is recruiting below its size-band peers.
11 of 67 indexed trials (16.4%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Alcoholism research.
National Institute on Alcohol Abuse and Alcoholism (NIAAA) accounts for 11 of 67 trials (16.4%). 34 distinct sponsors appear on at least one study for this condition label.
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Typical Alcoholism enrolment sits around 120 participants.
Median target enrolment is 120 among the 66 trials that report a genuine target (sentinel values excluded). 30 of those (45.5%) plan for fewer than 100 participants.
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Alcoholism research is mostly interventional.
56 interventional and 11 observational studies make up this index (83.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
67 total, page 1 of 2
SMART-r: Substance Monitoring and Active Relapse Tracking Repository
National Institute on Drug Abuse (NIDA)
NCT06676059
Characterization Imaging Instruments in Alcoholics and Non-Alcoholics
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT02108080
Behavioral and Functional Task Development, Implementation, and Testing
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT02108054
Alcohol and the Social Brain: an Alcohol-Administration Hyperscanning Study
University of Illinois at Urbana-Champaign
NCT06687525
Alcohol and the Social Brain: An Alcohol-Administration Hyperscanning Study Employing a Within-Subject Design
University of Illinois at Urbana-Champaign
NCT07125534
CRP and S&A for Inpatient Veterans
VA Office of Research and Development
NCT05054738
Safety and Effectiveness of the BrainsWay Deep Transcranial Magnetic Stimulation (Deep TMS) for Treatment of Alcohol Use Disorder (AUD)
Brainsway
NCT07216872
Suicidal Behavior in Patients Diagnosed With Bipolar Disorder
Emory University
NCT02604277
Naltrexone in AUD Reward Drinkers
University of Pennsylvania
NCT05028062
Ketamine Alcohol (in Treatment-Resistant Depression)
Mark Niciu
NCT02122562
Developing Functional Connectivity-Guided TMS for Alcohol Use Disorder
VA Palo Alto Health Care System
NCT06415721
Chicago Social Drinking Project
University of Chicago
NCT00961792
Behavioral Alcohol Responses (BAR) Study
Carnegie Mellon University
NCT03467191
Stand Down-Think Before You Drink: An RCT of a Mobile App for Hazardous Drinking With Peer Phone Support
VA Office of Research and Development
NCT05473598
Telehealth Treatment for Alcohol Use Disorder
Ria Health
NCT05747703
Ibudilast for Treating Alcohol Use Disorder
University of Pennsylvania
NCT05414240
Ultra-brief Intervention for Problem Drinkers
Centre for Addiction and Mental Health
NCT00688584
COMBINE (Acamprosate/Naltrexone)
University of North Carolina, Chapel Hill
NCT00006206
The Effect of Positive and Negative Emotions on Brain Activity in Alcoholics and Nonalcoholics
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT00001675
Acamprosate: Genes Associated With Response
Mayo Clinic
NCT00662571
Combined Pharmacotherapies for Alcoholism (Naltrexone/Ondansetron)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT00027079
A Randomized, Double-blind Placebo-Controlled Pharmacogenetic Study of Topiramate in European-American Heavy Drinkers
University of Pennsylvania
NCT02371889
Integrated Stepped Care for Unhealthy Alcohol Use in HIV
Yale University
NCT01410123
Managing Alcoholism in People Who Do Not Respond to Naltrexone
University of Pennsylvania
NCT00115037
Combination of Disulfiram Plus Naltrexone to Treat Both Cocaine- and Alcohol-dependent Individuals - 1
University of Pennsylvania
NCT00142844
Drug Therapy for Alcohol Dependence in Alaska Natives (Naltrexone/Sertraline)
Yale University
NCT00000451
Naltrexone, Craving, and Drinking
Brown University
NCT00006203
Individualized Assessment and Treatment for Alcoholism II
UConn Health
NCT03233802
Topiramate for Alcohol and Cocaine Dependence
Kyle Kampman
NCT00167245
Integrated Alcohol Disorder and PTSD Treatment
VA Office of Research and Development
NCT01601067
Adaptive Interventions for Problem Drinkers
Northwell Health
NCT02511808
Post-Treatment Effects of Naltrexone
Indiana University
NCT00006449
Gabapentin Treatment of Alcohol Dependence
The Scripps Research Institute
NCT00391716
Naltrexone for Heavy Drinking in Young Adults
Yale University
NCT00568958
Treatment With Mecamylamine in Smoking and Non-smoking Alcohol Dependent Patients
Yale University
NCT00342563
Sertraline Pharmacotherapy for Alcoholism Subtypes
UConn Health
NCT00368550
Chronic Alcohol and Brain Stress Circuit Response
Yale University
NCT01031264
Drug Treatment for Depressed Alcoholics (Naltrexone/Fluoxetine)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT00006204
Mifepristone Treatment of Alcohol Use Disorder
The Scripps Research Institute
NCT02179749
Imaging Cannabinoid CB1 Receptors in Alcohol Dependence
National Institute of Mental Health (NIMH)
NCT00816439
Naltrexone Treatment of Alcohol Abuse in Schizophrenia
State University of New York - Upstate Medical University
NCT00145847
The Effects of Oxytocin on Startle Hyperreactivity in Patients With AUD and PTSD
University of California, San Francisco
NCT02469259
A Study of LY2940094 in Participants With Alcohol Dependency
BlackThorn Therapeutics
NCT01798303
Matching Genotypes and Serotonergic Medications for Alcoholism
Brown University
NCT01113164
Aripiprazole for Bipolar Disorder and Alcohol Use Disorder
University of Texas Southwestern Medical Center
NCT02918370
GABA Mechanisms Underlying the Vulnerability to Alcohol Dependence
Yale University
NCT00611767
Repurposing alpha1 Noradrenergic Antagonists for Alcoholism Treatment
University of Wisconsin, Madison
NCT02966340
The Stress-Hormone System in Alcohol-Dependent Subjects
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00536146
The Effect of Naltrexone on Alcohol Craving and on Brain Activity During Alcohol Infusion
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT00667771
Effect of LY686017 on Alcohol Craving
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT00310427
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 10 |
| Phase 2 | 16 |
| Phase 3 | 3 |
| Phase 4 | 11 |
Top Sponsors
Named interventions
Most-linked intervention names on Alcoholism records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Alcoholism trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Alcoholism page
67 registered trials, 11 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 11 Alcoholism trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- National Institute on Alcohol Abuse and Alcoholism (NIAAA) sponsors the most Alcoholism trials on record, review their full trial history before evaluating a specific study. See National Institute on Alcohol Abuse and Alcoholism (NIAAA)'s trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Alcoholism condition card totals 67 registered trials; most-linked intervention Placebo; top US site state Connecticut. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.