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NCT05451953 · ClinicalTrials.gov registry record · NA

Providing Oxygen During Intubation in the NICU Trial

A NA study of Neonatal Respiratory Failure and Tracheal Intubation Morbidity, sponsored by University of Pennsylvania.

Recruiting
Registry status
NA
Development phase
110
Enrollment target
1
Study location

NCT05451953 is a NA study of Neonatal Respiratory Failure and Tracheal Intubation Morbidity that is actively recruiting participants, run by University of Pennsylvania. The registered enrollment target is 110 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT05451953, a NA study of Neonatal Respiratory Failure and Tracheal Intubation Morbidity, is actively recruiting participants, sponsored by University of Pennsylvania.

RECRUITING
Registry status
NA
Development phase
110 participants
Enrollment target
1
Study location

Study Summary

Tracheal intubation in the NICU is frequently complicated by severe oxygen desaturation. Apneic oxygenation, a method of applying free flowing oxygen via nasal cannula to apneic patients undergoing intubation, prevents or delays oxygen desaturation during intubation in adults and older children. We propose to enroll patients at two sites (Hospital of the University of Pennsylvania and Children's Hospital of Philadelphia) in a randomized trial in infants undergoing intubation in the NICU to determine if apneic oxygenation, compared with no respiratory support or oxygen during laryngoscopy and intubation attempts (standard care), reduces the magnitude of oxygen desaturation during tracheal intubation encounters.

Interventions

  • PROCEDURE Standard of Care
  • PROCEDURE Apneic Oxygenation

Study Locations (1)

Pennsylvania

  • University of Pennsylvania - Philadelphia

Trial Details

FieldValue
Enrollment Target 110 participants
Start Date 2022-07-20
Est. Completion 2027-02-28
Phase NA

Sponsor

University of Pennsylvania

1,423 total trials

What the Registry Record Tells You About NCT05451953

The ClinicalTrials.gov registry entry for NCT05451953 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 110 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Pennsylvania, which has 1,423 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Neonatal Respiratory Failure appearing as the primary indexed condition, and to 2 interventions - of which Standard of Care is the first listed.

NCT05451953 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT05451953 about?

NCT05451953 is a clinical study titled "Providing Oxygen During Intubation in the NICU Trial". Tracheal intubation in the NICU is frequently complicated by severe oxygen desaturation. Apneic oxygenation, a method of applying free flowing oxygen via nasal cannula to apneic patients undergoing intubation, prevents or delays oxygen desaturation during intubation in adults and older children. We ...

What is the current status of trial NCT05451953?

This trial is currently recruiting. It is a NA study. The enrollment target is 110 participants. The study started on 2022-07-20. Estimated completion is 2027-02-28.

What conditions does trial NCT05451953 study?

This clinical trial studies the following conditions: Neonatal Respiratory Failure, Tracheal Intubation Morbidity.

What interventions are being tested in trial NCT05451953?

The interventions under investigation include: Standard of Care (PROCEDURE), Apneic Oxygenation (PROCEDURE).

Who is sponsoring clinical trial NCT05451953?

This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05451953 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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