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NCT06540976 · ClinicalTrials.gov registry record · NA
Posterior Cingulate Cortex and Executive Control of Episodic Memory
A NA study of Episodic Memory, sponsored by University of Pennsylvania.
- Recruiting
- Registry status
- NA
- Development phase
- 130
- Enrollment target
- 1
- Study location
NCT06540976 is a NA study of Episodic Memory that is actively recruiting participants, run by University of Pennsylvania. The registered enrollment target is 130 participants. The trial reports 1 study location across 1 state.
The verdict
NCT06540976, a NA study of Episodic Memory, is actively recruiting participants, sponsored by University of Pennsylvania.
- RECRUITING
- Registry status
- NA
- Development phase
- 130 participants
- Enrollment target
- 1
- Study location
Study Summary
This project will use intracranial recordings and stimulation of the human brain to understand the unique contributions of the posterior cingulate cortex (PCC) to episodic memory behavior. The goal is to test how distinct subregions of the PCC differentially contribute to memory-based decisions (e.g., have I seen this picture before?). The ability to perform invasive studies of the human brain is through routine clinical monitoring of brain activity which occurs during the neurosurgical treatment of epilepsy. However, this project only focuses on the basic science of PCC and memory behavior. Specifically, the investigators will use single-0cell and population measures of brain activity to test a new theory of PCC function which focuses on the executive processes needed to support memory retrieval and memory-based decisions. By studying the PCC, a convergence zone of memory and executive brain systems, progress can be made in elucidating how the failure to successfully leverage past experiences in daily behavior can occur as a common symptom of both neurodegenerative disease (e.g., Alzheimer's disease) and multiple psychiatric conditions (e.g., schizophrenia) implicating PCC dysfunction.
Conditions Studied
Interventions
- BEHAVIORAL Cognitive testing
Study Locations (1)
Pennsylvania
- Hospital of the University of Pennsylvania - Pavilion - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 130 participants |
| Start Date | 2023-01-18 |
| Est. Completion | 2027-04-30 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06540976
The ClinicalTrials.gov registry entry for NCT06540976 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 130 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Pennsylvania, which has 1,423 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Episodic Memory appearing as the primary indexed condition, and to 1 intervention - of which Cognitive testing is the first listed.
NCT06540976 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT06540976 about?
NCT06540976 is a clinical study titled "Posterior Cingulate Cortex and Executive Control of Episodic Memory". This project will use intracranial recordings and stimulation of the human brain to understand the unique contributions of the posterior cingulate cortex (PCC) to episodic memory behavior. The goal is to test how distinct subregions of the PCC differentially contribute to memory-based decisions (e.g...
What is the current status of trial NCT06540976?
This trial is currently recruiting. It is a NA study. The enrollment target is 130 participants. The study started on 2023-01-18. Estimated completion is 2027-04-30.
What conditions does trial NCT06540976 study?
This clinical trial studies the following conditions: Episodic Memory.
What interventions are being tested in trial NCT06540976?
The interventions under investigation include: Cognitive testing (BEHAVIORAL).
Who is sponsoring clinical trial NCT06540976?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06540976 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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