University of Chicago

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, University of Chicago sits in the top decile of US sponsors by registered trial count (#41 of 15,742 sponsors by registered trial count).

796 total trials 158 currently recruiting 451 completed early-phase tilt top decile by trial count

University of Chicago: 796 sponsored US clinical trials, 158 recruiting.

University of Chicago sponsors 796 registered US clinical trials on ClinicalTrials.gov, 158 of them currently recruiting, and 451 completed. 67 of these trials are in Phase 3-4 (later-stage) and 293 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Prostate Cancer, with 11 trials.

Top-decile sponsor footprint

University of Chicago ranks in the top decile of sponsors by registered trial count (#41 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 40/100

451 of 562 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (80.2%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

796 total, page 4 of 16

RECRUITING Phase 4

Vasoactive Drugs in Intensive Care Unit

NCT02118467

RECRUITING NA

Islet Transplantation in Patients With "Brittle" Type I Diabetes

NCT01630850

RECRUITING

The 1200 Patients Project: Studying the Implementation of Clinical Pharmacogenomic Testing

NCT01280825

RECRUITING Phase 2

Islet Transplantation in Type 1 Diabetic Kidney Allograft

NCT01241864

RECRUITING

Tissue Procurement for Gastric Cancer, Gastrointestinal Stromal Tumors (GIST), Esophageal Cancer, Pancreas Cancer, Hepatocellular Cancer, Biliary Cancer, Neuroendocrine, Peritoneal Mesothelioma, Anal Cancer and Colorectal Cancer in Patients Undergoing Surgery or Biopsy

NCT01416714

RECRUITING

Explanted Lung Tissues With Pulmonary Fibrosis

NCT00515567

RECRUITING

A Study of the Natural Progression of Interstitial Lung Disease (ILD)

NCT00470327

RECRUITING

Genetics of Cardiovascular and Neuromuscular Disease

NCT00138931

ACTIVE NOT RECRUITING NA

Achieving Equity in Patient Outcome Reporting for Timely Assessments of Life With HIV and Substance Use

NCT06682468

ACTIVE NOT RECRUITING

The Sinonasal Microbiome

NCT06822725

ACTIVE NOT RECRUITING NA

Communication Bridge Pilot Study

NCT06211374

ACTIVE NOT RECRUITING Phase 2

Virtual Diabetes Group Visits Across Health Systems

NCT06094491

ACTIVE NOT RECRUITING Phase 1

Study of Xevinapant With Radiation and Chemotherapy for Patients With Head and Neck Cancer

NCT06110195

ACTIVE NOT RECRUITING Phase 2

Behavioral Treatment and Memantine in Body Focused Repetitive Behaviors

NCT05796752

ACTIVE NOT RECRUITING Phase 2

A Clinical Trial of Tolcapone in Obsessive Compulsive Disorder

NCT05624528

ACTIVE NOT RECRUITING NA

Physical Activity Intervention for Black Women With Asthma

NCT05726487

ACTIVE NOT RECRUITING NA

Basic Experimental Study of Hippocampal Memory Functions

NCT05945628

ACTIVE NOT RECRUITING NA

Guideline-directed Management and Therapy (GDMT) for the Prevention of Postpartum Cardiac Dysfunction in Preeclamptic African American Women

NCT05534932

ACTIVE NOT RECRUITING NA

Voice-Activated Technology to Improve Mobility in Multimorbid, Frail, Homebound Older Adults (EngAGE)

NCT05337514

ACTIVE NOT RECRUITING Early Phase 1

Collaborative Urological Prosthetics Investigation Directive Research Group

NCT05100654

ACTIVE NOT RECRUITING NA

Radiation Dose Study for Relapsed/Refractory Hodgkin/Non-Hodgkin Lymphoma

NCT05019976

ACTIVE NOT RECRUITING NA

Comparing Meniscal Repair Biologic Augmentation: Marrow Venting Procedure Versus PRP (MVP Trial)

NCT04775004

ACTIVE NOT RECRUITING Phase 2

Assessing the Efficacy of Sirolimus in Patients With COVID-19 Pneumonia for Prevention of Post-COVID Fibrosis

NCT04948203

ACTIVE NOT RECRUITING NA

Technology-Supported Treatment of Sleep Apnea in Prediabetes

NCT04225507

ACTIVE NOT RECRUITING NA

Using Technology to Address Disparities and Promote Healthcare Equity in Type 1 Diabetes Registry

NCT06899984

ACTIVE NOT RECRUITING

Alterations of the Microbiome During Critical Illness With Short and Long Term Clinical Outcomes

NCT04552834

ACTIVE NOT RECRUITING

Biomarkers of CASH

NCT04467489

ACTIVE NOT RECRUITING

Long Term Outcomes of Patients With COVID-19

NCT04360538

ACTIVE NOT RECRUITING Phase 1

Study of Venetoclax in Combination With Decitabine in Subjects With Acute Myeloid Leukemia

NCT03844815

ACTIVE NOT RECRUITING NA

Study to Assess for Measurable Residual Disease (MRD) in Multiple Myeloma Patients

NCT04108624

ACTIVE NOT RECRUITING Phase 2

Pembrolizumab in Combination With Chemotherapy for Patients With Untreated B Cell Lymphoma

NCT03995147

ACTIVE NOT RECRUITING

Plasma 5hmC Signatures as a Marker of Colorectal / Appendiceal Peritoneal Metastasis

NCT04157322

ACTIVE NOT RECRUITING Phase 3

Carfilzomib, Lenalidomide, and Dexamethasone Versus Bortezomib, Lenalidomide and Dexamethasone (KRd vs. VRd) in Patients With Newly Diagnosed Multiple Myeloma (COBRA)

NCT03729804

ACTIVE NOT RECRUITING Phase 2

Daratumumab, Carfilzomib, Lenalidomide and Low Dose Dexamethasone (DKRd) in Newly Diagnosed, Multiple Myeloma

NCT03500445

ACTIVE NOT RECRUITING Phase 1

Study of Drug 1 (Enzalutamide) Plus Drug 2 (Relacorilant) for Patients With Prostate Cancer

NCT03674814

ACTIVE NOT RECRUITING NA

An Early Real-Time Electronic Health Record Risk Algorithm for the Prevention and Treatment of Acute Kidney Injury

NCT03590028

ACTIVE NOT RECRUITING Phase 2

Pembrolizumab With Chemotherapy for Poorly Chemo-responsive Thyroid and Salivary Gland Tumors

NCT03360890

ACTIVE NOT RECRUITING NA

Behavioral Chronotype: Impact on Sleep and Metabolism

NCT03647306

ACTIVE NOT RECRUITING Phase 1

Combination of Pembrolizumab With TGR-1202 in Patients With Relapsed/Refractory CLL and B-cell NHL

NCT03283137

ACTIVE NOT RECRUITING NA

Supportive Release Center Study

NCT03616990

ACTIVE NOT RECRUITING NA

Nature Sounds as a Pain and Anxiety Reducing Strategy in Patients Undergoing Breast Core Biopsy

NCT03238976

ACTIVE NOT RECRUITING Phase 1

Concurrent or Sequential Immunotherapy and Radiation Therapy in Patients With Metastatic Lung Cancer

NCT03223155

ACTIVE NOT RECRUITING

Study to Determine if Patients Exposed to General Anesthesia Significant Numbers of Times Would Increase the Risk for Intraoperative Awareness.

NCT05857618

ACTIVE NOT RECRUITING

Wearable Gait Sensors

NCT06628934

ACTIVE NOT RECRUITING Phase 2

A Randomized, Double-Blind Phase II Study of Adjuvant Pembrolizumab Versus Placebo in Head and Neck Cancers at High Risk for Recurrence- the PATHWay Study

NCT02841748

ACTIVE NOT RECRUITING Phase 2

Abraxane® With or Without Mifepristone for Advanced, Glucocorticoid Receptor-Positive, Triple-Negative Breast Cancer

NCT02788981

ACTIVE NOT RECRUITING Phase 2

Pembrolizumab and Ipilimumab After Prior Immunotherapy for Melanoma

NCT02743819

ACTIVE NOT RECRUITING Phase 3

Trial of Carfilzomib, Lenalidomide, Dexamethasone Versus Lenalidomide Alone After Stem-cell Transplant for Multiple Myeloma

NCT02659293

ACTIVE NOT RECRUITING NA

Random Evaluation of Patients Who Have Had Laparoscopic Partial Nephrectomy

NCT04120805

ACTIVE NOT RECRUITING NA

Improving Maternal and Child Health Through Prenatal Fatty Acid Supplementation

NCT02647723

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Phase Distribution

PhaseTrial count
Phase 1 137
Phase 2 156
Phase 3 14
Phase 4 53

What is open in the University of Chicago pipeline

158 recruiting of 796 indexed (20% open); 451 completed (57%).

Phase mix: 67 late (III/IV) vs 293 early (I/II) (early-phase heavy).

Top condition: Prostate Cancer (11 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

University of Chicago: open-pipeline peers nationwide

Peers matched on 796 registered trials and 20% open enrollment, not the therapeutic-area sidebar.

University of Chicago sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 02004006008001,000 14%16%18%20%22% Total trials Recruiting share University of ChicagoDana-Farber Cancer InstituteUniversity of California, San DiegoUniversity of UtahUniversity of Texas Southwestern Medical CenterAcera SurgicalAlign TechnologyAltruBioAlvernia University
University of Chicago sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

University of Chicago sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 796 trials (± recruiting share)

Sponsors near 20% open enrollment (± trial volume)

What to do with this University of Chicago page

796 registered trials is a research-attention snapshot, not an endorsement of University of Chicago or any single study.

  • 158 of University of Chicago's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Prostate Cancer is the condition University of Chicago studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Prostate Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

University of Chicago pipeline card: 796 registered trials from official public datasets.Report a data error.