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NCT02659293 · ClinicalTrials.gov registry record · Phase 3
Trial of Carfilzomib, Lenalidomide, Dexamethasone Versus Lenalidomide Alone After Stem-cell Transplant for Multiple Myeloma
A Phase 3 study of Multiple Myeloma, sponsored by University of Chicago.
- Active
- Registry status
- Phase 3
- Development phase
- 180
- Enrollment target
- 3
- Study locations
NCT02659293: Active Phase 3 study of Multiple Myeloma, sponsored by University of Chicago.
NCT02659293 is a Phase 3 study of Multiple Myeloma that is active but no longer recruiting, run by University of Chicago. The registered enrollment target is 180 participants, below the 546-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (67% lower). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02659293, a Phase 3 study of Multiple Myeloma, is active but no longer recruiting, sponsored by University of Chicago.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 3
- Development phase
- 180 participants
- Enrollment target
- 3
- Study locations
Study Summary
This is a Phase 3 randomized trial of carfilzomib, lenalidomide, dexamethasone versus lenalidomide alone after stem-cell transplant for multiple myeloma, eligible to subjects who completed autologous stem cell transplant for symptomatic myeloma who are considered for lenalidomide maintenance.
Primary Outcome
Measurement of time to disease worsening as measured by International Myeloma Working Group (IMWG) response criteria.
Conditions Studied
Interventions
- DRUG Dexamethasone
- DRUG Lenalidomide
- DRUG Carfilzomib
- DRUG Lenalidomide (Control)
Study Locations (3)
Illinois
- University of Chicago - Chicago
Michigan
- Wayne State University - Karmanos Cacner Institute - Detroit
Other
- Polish Myeloma Consortium - Poznan
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 180 participants |
| Start Date | 2016-04-26 |
| Est. Completion | 2027-11 |
| Phase | Phase 3 |
What the registry record for NCT02659293 still lists
NCT02659293 is an interventional study that assigns participants to a tested intervention. The registered 180 participants enrollment target is mid-sized for trials with a published cap, below the 546-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (67% lower).
The record links to 1 condition, with Multiple Myeloma appearing as the primary indexed condition, and to 4 interventions - of which Dexamethasone is the first listed.
NCT02659293 reports a single indexed study location in Illinois, Michigan, Other.
Frequently Asked Questions
What is clinical trial NCT02659293 about?
NCT02659293 is a clinical study titled "Trial of Carfilzomib, Lenalidomide, Dexamethasone Versus Lenalidomide Alone After Stem-cell Transplant for Multiple Myeloma". This is a Phase 3 randomized trial of carfilzomib, lenalidomide, dexamethasone versus lenalidomide alone after stem-cell transplant for multiple myeloma, eligible to subjects who completed autologous stem cell transplant for symptomatic myeloma who are considered for lenalidomide maintenance.
What is the current status of trial NCT02659293?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 180 participants. The study started on 2016-04-26. Estimated completion is 2027-11.
What conditions does trial NCT02659293 study?
This clinical trial studies the following conditions: Multiple Myeloma.
What interventions are being tested in trial NCT02659293?
The interventions under investigation include: Dexamethasone (DRUG), Lenalidomide (DRUG), Carfilzomib (DRUG), Lenalidomide (Control) (DRUG).
Who is sponsoring clinical trial NCT02659293?
This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02659293 being conducted?
This trial has 3 study locations across Illinois, Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Multiple Myeloma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02659293's enrollment target sits among peer trials
180 119th of 438 higher than 318 of 438 other Multiple Myeloma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Multiple Myeloma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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