Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT04467489 · ClinicalTrials.gov registry record

Biomarkers of CASH

A clinical trial of Cerebral Cavernous Malformation and Cavernous Angioma, sponsored by University of Chicago.

Active
Registry status
1,040
Enrollment target
4
Study locations

NCT04467489 is a study of Cerebral Cavernous Malformation and Cavernous Angioma that is active but no longer recruiting, run by University of Chicago. The registered enrollment target is 1,040 participants. The trial reports 4 study locations across 4 states.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT04467489, a study of Cerebral Cavernous Malformation and Cavernous Angioma, is active but no longer recruiting, sponsored by University of Chicago.

ACTIVE NOT RECRUITING
Registry status
1,040 participants
Enrollment target
4
Study locations

Study Summary

The project aims to develop prognostic and diagnostic blood tests for symptomatic brain hemorrhage in patients diagnosed with cavernous angiomas, a critical clinical challenge in a disease affecting more than a million Americans. We further examine whether blood biomarkers can replace or enhance the accuracy of advanced imaging in association with lesional bleeding. The project tests a novel integrational approach of biomarker development in a mechanistically defined cerebrovascular disease, with a clinically relevant context of use.

Interventions

  • OTHER observational

Study Locations (4)

Arizona

  • Barrow Neurological Institute at St. Joseph's Hospital and Medical Center - Phoenix

California

  • University of California, San Francisco - San Francisco

Illinois

  • The University of Chicago Medical Center - Chicago

Minnesota

  • Mayo Clinic - Rochester

Trial Details

FieldValue
Enrollment Target 1,040 participants
Start Date 2020-05-22
Est. Completion 2026-06-30

Sponsor

University of Chicago

796 total trials

What the Registry Record Tells You About NCT04467489

The ClinicalTrials.gov registry entry for NCT04467489 describes a study currently listed as active not recruiting, categorized as an unspecified phase. The registered enrollment target is 1,040 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Chicago, which has 796 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Cerebral Cavernous Malformation appearing as the primary indexed condition, and to 1 intervention - of which observational is the first listed.

NCT04467489 reports 4 study locations spanning 4 distinct geographic areas - top geographies include Arizona, California, Illinois.

Frequently Asked Questions

What is clinical trial NCT04467489 about?

NCT04467489 is a clinical study titled "Biomarkers of CASH". The project aims to develop prognostic and diagnostic blood tests for symptomatic brain hemorrhage in patients diagnosed with cavernous angiomas, a critical clinical challenge in a disease affecting more than a million Americans. We further examine whether blood biomarkers can replace or enhance the...

What is the current status of trial NCT04467489?

This trial is currently active not recruiting. The enrollment target is 1,040 participants. The study started on 2020-05-22. Estimated completion is 2026-06-30.

What conditions does trial NCT04467489 study?

This clinical trial studies the following conditions: Cerebral Cavernous Malformation, Cavernous Angioma, Hemorrhagic Microangiopathy.

What interventions are being tested in trial NCT04467489?

The interventions under investigation include: observational (OTHER).

Who is sponsoring clinical trial NCT04467489?

This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04467489 being conducted?

This trial has 4 study locations across Arizona, California, Illinois, Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Cerebral Cavernous Malformation

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.