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NCT04948203 · ClinicalTrials.gov registry record · Phase 2

Assessing the Efficacy of Sirolimus in Patients With COVID-19 Pneumonia for Prevention of Post-COVID Fibrosis

A Phase 2 study of Long COVID and Pulmonary Fibrosis, sponsored by University of Chicago.

Active
Registry status
Phase 2
Development phase
60
Enrollment target
1
Study location

NCT04948203: Active Phase 2 study of Long COVID and Pulmonary Fibrosis, sponsored by University of Chicago.

NCT04948203 is a Phase 2 study of Long COVID and Pulmonary Fibrosis that is active but no longer recruiting, run by University of Chicago. The registered enrollment target is 60 participants, below the 2,187-participant average among 50 other Long COVID trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04948203, a Phase 2 study of Long COVID and Pulmonary Fibrosis, is active but no longer recruiting, sponsored by University of Chicago.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
60 participants
Enrollment target
1
Study location

Study Summary

The primary purpose of this study is to determine whether the drug sirolimus reduces the likelihood of developing of pulmonary fibrosis in patients who are hospitalized with COVID-19 pneumonia.

Primary Outcome

Number of patients with \>10% pulmonary fibrosis on chest CT

Interventions

  • DRUG Sirolimus

Study Locations (1)

Illinois

  • University of Chicago - Chicago

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2021-07-09
Est. Completion 2026-12
Phase Phase 2
University of Chicago

796 total trials

What the registry record for NCT04948203 still lists

NCT04948203 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 2,187-participant average among 50 other Long COVID trials with a reported enrollment target (97% lower).

The record links to 3 conditions, with Long COVID appearing as the primary indexed condition, and to 1 intervention - of which Sirolimus is the first listed.

NCT04948203 reports a single indexed study location in Illinois.

Frequently Asked Questions

What is clinical trial NCT04948203 about?

NCT04948203 is a clinical study titled "Assessing the Efficacy of Sirolimus in Patients With COVID-19 Pneumonia for Prevention of Post-COVID Fibrosis". The primary purpose of this study is to determine whether the drug sirolimus reduces the likelihood of developing of pulmonary fibrosis in patients who are hospitalized with COVID-19 pneumonia.

What is the current status of trial NCT04948203?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2021-07-09. Estimated completion is 2026-12.

What conditions does trial NCT04948203 study?

This clinical trial studies the following conditions: Long COVID, Pulmonary Fibrosis, COVID-19 Pneumonia.

What interventions are being tested in trial NCT04948203?

The interventions under investigation include: Sirolimus (DRUG).

Who is sponsoring clinical trial NCT04948203?

This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04948203 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Long COVID

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04948203's enrollment target sits among peer trials

60 27th of 50 higher than 20 of 50 other Long COVID trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Long COVID trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04948203, the US trial registry maintained by the National Library of Medicine. NCT04948203 (small enrollment · single site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.