University of Chicago

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, University of Chicago sits in the top decile of US sponsors by registered trial count (#41 of 15,742 sponsors by registered trial count).

796 total trials 158 currently recruiting 451 completed early-phase tilt top decile by trial count

University of Chicago: 796 sponsored US clinical trials, 158 recruiting.

University of Chicago sponsors 796 registered US clinical trials on ClinicalTrials.gov, 158 of them currently recruiting, and 451 completed. 67 of these trials are in Phase 3-4 (later-stage) and 293 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Prostate Cancer, with 11 trials.

Top-decile sponsor footprint

University of Chicago ranks in the top decile of sponsors by registered trial count (#41 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 40/100

451 of 562 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (80.2%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

796 total, page 3 of 16

RECRUITING NA

Effect of Cooling Therapy for Post-Operative Pain in Open Carpal Tunnel Release

NCT05783245

RECRUITING NA

Interactive Computer-adaptive Chronic Kidney Disease Education Program

NCT06364358

RECRUITING Phase 2

Study of Belantamab Mafodotin With Carfilzomib, Pomalidomide, and Dexamethasone in Relapsed Multiple Myeloma

NCT05789303

RECRUITING NA

LH Canine Therapy Study

NCT05840198

RECRUITING NA

MRI Risk Maps for Prostate Cancer Diagnosis Using Targeted Biopsy

NCT05710380

RECRUITING Phase 2

Tocilizumab for Acute Chest Syndrome

NCT05640271

RECRUITING Phase 1

Dosing Study of Radiation Combined With Tislelizumab and Pamiparib in Patients With Previously Treated Head and Neck Cancer

NCT05526924

RECRUITING

Predict Severe Traumatic Brain Injury

NCT06966713

RECRUITING NA

Hybrid Type I Effectiveness-Implementation Trial of a Social Network Support Intervention

NCT05723653

RECRUITING NA

GI Oxalate Absorption

NCT05356000

RECRUITING

At-home Walking Cadence Functional Assessment and Recovery Trajectory for Older Adults Undergoing Major Surgery

NCT05886725

RECRUITING NA

Evaluating Personalized Therapeutics Clinic (PTC) on Drug-Drug Interactions and Drug-Gene Interactions

NCT05166694

RECRUITING NA

Oxalate and Citrate

NCT05334979

RECRUITING Phase 2

A Study of Pembrolizumab in Combination With Chemotherapy for Head and Neck Cancer

NCT05420948

RECRUITING NA

Case Management Dyad

NCT06162897

RECRUITING Phase 1

A Study of VS-6766 and Cetuximab in Patients With Advanced Colorectal Cancer

NCT05200442

RECRUITING Phase 2

Durvalumab and Ablative Radiation in Small Cell Lung Cancer (DARES)

NCT05068232

RECRUITING Phase 4

Impact of Anti-inflammatory Medications in Patients With Elevated Serum Prostate-specific Antigen

NCT05512754

RECRUITING

MAsS Scan as a Predictor of Morbidity and Mortality in Patients With Liver Disease

NCT05264051

RECRUITING NA

MRI Screening in Men at High Risk of Developing Prostate Cancer

NCT05608694

RECRUITING NA

The Reducing REVISITS Study: A Cluster RCT

NCT05568043

RECRUITING NA

The PhOCus Trial: Implementation of Pharmacogenomic Testing in Oncology Care

NCT04541381

RECRUITING

Diabetic Neuropathy in Spinal Cord Stimulator Patients

NCT04687215

RECRUITING Phase 2

Nitrous Oxide as Treatment for Fibromyalgia

NCT05357066

RECRUITING NA

Reducing Opioid Mortality in Illinois

NCT04925427

RECRUITING Phase 2

Antidepressant Effects of Nitrous Oxide

NCT05357040

RECRUITING NA

Variable Immobilization Protocol for Arthroplasty of the Carpometacarpal Joint of the Thumb

NCT04828954

RECRUITING

Intermuscular Coherence as a Biomarker for ALS

NCT05104710

RECRUITING Phase 2

Study of Chemotherapy-Free Induction Regimen for Ph+ Acute Lymphoblastic Leukemia With Inotuzumab Ozogamicin (InO)

NCT04747912

RECRUITING Phase 2

Olaparib in Patients With HRD Malignant Mesothelioma

NCT04515836

RECRUITING Phase 4

Aspirin and Preeclampsia

NCT04479072

RECRUITING Phase 1

Study of Pelvic Hypofractionated Radiotherapy in Endometrial Cancer

NCT04683653

RECRUITING NA

Effect of Education on Treatment Decision Making for Patients With Prostate Cancer on Chronic Hormone Treatments

NCT04705038

RECRUITING NA

Gut Microbiome and Sex as Risk Factors for Kidney Stones After Bariatric Surgery

NCT04590690

RECRUITING

Detecting HPV DNA in Anal and Cervical Cancers

NCT04857528

RECRUITING

Efficacy Of Hiatal Closure For GERD

NCT06280664

RECRUITING NA

Point of Care Testing for Presence of Current and or Previous T. Gondii Infection

NCT04474132

RECRUITING Phase 1

Comparing Dosing Intervals of Nivolumab or Pembrolizumab in Locally Advanced or Metastatic Cancers

NCT04295863

RECRUITING Phase 1

Safety of Combining Irinotecan With 5-FU, Leucovorin/Folinic Acid, Oxaliplatin, and Docetaxel Chemotherapies

NCT04361708

RECRUITING NA

Mechanisms of Prediabetic States in Sleep Apnea

NCT04234217

RECRUITING NA

A Multi-Modality Surveillance Program for Women at High Risk for Breast Cancer

NCT03729115

RECRUITING Phase 1

Ruxolitinib and Chemotherapy in Adolescents and Young Adults With Ph-like Acute Lymphoblastic Leukemia

NCT03571321

RECRUITING NA

Comprehensive Care Community and Culture Study

NCT04489693

RECRUITING NA

Volume Support/Assist Control Mode Ventilation and Diaphragmatic Atrophy

NCT03901924

RECRUITING NA

The ImPreSS Trial: Pharmacogenomic Decision Making at Time of Surgery

NCT03729180

RECRUITING NA

Forceps vs. Snare IVC Filter Removal

NCT04092192

RECRUITING Phase 1

Selumetinib and Azacitidine in High Risk Chronic Blood Cancers

NCT03326310

RECRUITING

Implementation of Point-of-Care Pharmacogenomic Decision Support Accounting for Minority Disparities

NCT03225820

RECRUITING Phase 4

Genetic Analysis-Guided Irinotecan Hydrochloride Dosing of mFOLFIRINOX in Treating Patients With Locally Advanced Gastroesophageal or Stomach Cancer

NCT02366819

RECRUITING Phase 1

Intensity Modulated Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients With Relapsed Hematologic Cancers Undergoing a Second Donor Stem Cell Transplant

NCT02333162

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Phase Distribution

PhaseTrial count
Phase 1 137
Phase 2 156
Phase 3 14
Phase 4 53

What is open in the University of Chicago pipeline

158 recruiting of 796 indexed (20% open); 451 completed (57%).

Phase mix: 67 late (III/IV) vs 293 early (I/II) (early-phase heavy).

Top condition: Prostate Cancer (11 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

University of Chicago: open-pipeline peers nationwide

Peers matched on 796 registered trials and 20% open enrollment, not the therapeutic-area sidebar.

University of Chicago sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 02004006008001,000 14%16%18%20%22% Total trials Recruiting share University of ChicagoDana-Farber Cancer InstituteUniversity of California, San DiegoUniversity of UtahUniversity of Texas Southwestern Medical CenterAcera SurgicalAlign TechnologyAltruBioAlvernia University
University of Chicago sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

University of Chicago sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 796 trials (± recruiting share)

Sponsors near 20% open enrollment (± trial volume)

What to do with this University of Chicago page

796 registered trials is a research-attention snapshot, not an endorsement of University of Chicago or any single study.

  • 158 of University of Chicago's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Prostate Cancer is the condition University of Chicago studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Prostate Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

University of Chicago pipeline card: 796 registered trials from official public datasets.Report a data error.