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NCT02366819 · ClinicalTrials.gov registry record · Phase 4
Genetic Analysis-Guided Irinotecan Hydrochloride Dosing of mFOLFIRINOX in Treating Patients With Locally Advanced Gastroesophageal or Stomach Cancer
A Phase 4 study of Gastric Adenocarcinoma and Esophageal Adenocarcinoma, sponsored by University of Chicago.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 36
- Enrollment target
- 3
- Study locations
NCT02366819: Recruiting Phase 4 study of Gastric Adenocarcinoma and Esophageal Adenocarcinoma, sponsored by University of Chicago.
NCT02366819 is a Phase 4 study of Gastric Adenocarcinoma and Esophageal Adenocarcinoma that is actively recruiting participants, run by University of Chicago. The registered enrollment target is 36 participants, below the 245-participant average among 47 other Gastric Adenocarcinoma trials with a reported enrollment target (85% lower). The trial reports 3 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02366819, a Phase 4 study of Gastric Adenocarcinoma and Esophageal Adenocarcinoma, is actively recruiting participants, sponsored by University of Chicago.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 36 participants
- Enrollment target
- 3
- Study locations
Study Summary
This pilot clinical trial studies genetic analysis-guided irontecan hydrochloride dosing of modified fluorouracil, irinotecan hydrochloride, leucovorin calcium, oxaliplatin (mFOLFIRINOX) in treating patients with gastroesophageal or stomach cancer that has spread from where it started to nearby tissue or lymph nodes. Drugs used in chemotherapy, such as fluorouracil, irinotecan hydrochloride, leucovorin calcium, and oxaliplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Leucovorin calcium may also help fluorouracil work better. Genetic analysis may help doctors determine what dose of irinotecan hydrochloride patients can tolerate.
Conditions Studied
Interventions
- DRUG Fluorouracil
- DRUG Oxaliplatin
- DRUG Irinotecan Hydrochloride
- DRUG Leucovorin Calcium
- PROCEDURE Conventional Surgery
Study Locations (3)
Illinois
- University of Chicago Comprehensive Cancer Center - Chicago
- Kellogg Cancer Center - Evanston Hospital - Evanston
- NorthShore University HealthSystem - Evanston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2014-12-11 |
| Est. Completion | 2026-06-08 |
| Phase | Phase 4 |
What NCT02366819 shows while recruiting
NCT02366819 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 245-participant average among 47 other Gastric Adenocarcinoma trials with a reported enrollment target (85% lower).
The record links to 9 conditions, with Gastric Adenocarcinoma appearing as the primary indexed condition, and to 5 interventions - of which Fluorouracil is the first listed.
NCT02366819 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT02366819 about?
NCT02366819 is a clinical study titled "Genetic Analysis-Guided Irinotecan Hydrochloride Dosing of mFOLFIRINOX in Treating Patients With Locally Advanced Gastroesophageal or Stomach Cancer". This pilot clinical trial studies genetic analysis-guided irontecan hydrochloride dosing of modified fluorouracil, irinotecan hydrochloride, leucovorin calcium, oxaliplatin (mFOLFIRINOX) in treating patients with gastroesophageal or stomach cancer that has spread from where it started to nearby tiss...
What is the current status of trial NCT02366819?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 36 participants. The study started on 2014-12-11. Estimated completion is 2026-06-08.
What conditions does trial NCT02366819 study?
This clinical trial studies the following conditions: Gastric Adenocarcinoma, Esophageal Adenocarcinoma, Stage IIIB Gastric Cancer, Stage IIIA Gastric Cancer, Stage IIIB Esophageal Adenocarcinoma.
What interventions are being tested in trial NCT02366819?
The interventions under investigation include: Fluorouracil (DRUG), Oxaliplatin (DRUG), Irinotecan Hydrochloride (DRUG), Leucovorin Calcium (DRUG), Conventional Surgery (PROCEDURE).
Who is sponsoring clinical trial NCT02366819?
This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02366819 being conducted?
This trial has 3 study locations across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT02366819's enrollment target sits among peer trials
36 34th of 47 higher than 14 of 47 other Gastric Adenocarcinoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Gastric Adenocarcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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