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Reducing Opioid Mortality in Illinois
NCT04925427 · View on ClinicalTrials.gov ↗
Study Summary
Reducing Opioid Mortality in Illinois (ROMI) is 5-year research study led by the University of Chicago in partnership with the University of Illinois at Chicago's (UIC) Community Outreach Intervention Projects (COIP), the Illinois Criminal Justice Information Authority (ICJIA) and the American Institutes for Research (AIR). ROMI aims to understand and test strategies for linking individuals with a history of opioid use disorder who are released from Illinois jails and prisons to substance use treatment. ROMI is one of twelve grants awarded by the National Institutes of Health (NIH) as part of the Justice Community Opioid Innovation Network (JCOIN) to support research on quality addiction treatment for opioid use disorder in criminal justice settings nationwide.
Conditions Studied
Interventions
- BEHAVIORAL Case Management and Peer Recovery
- BEHAVIORAL Naloxone-Only
Study Locations (5)
Illinois
- Cook County Department of Corrections — Chicago
- Jackson County Jail — Murphysboro
- LaSalle County Jail — Ottawa
- Illinois Department of Corrections — Springfield
- Lake County Sheriff's Office Corrections Division — Waukegan
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,500 participants |
| Start Date | 2021-08-10 |
| Est. Completion | 2026-08-30 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04925427
The ClinicalTrials.gov registry entry for NCT04925427 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 1,500 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Chicago, which has 846 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Opioid Use appearing as the primary indexed condition, and to 2 interventions — of which Case Management and Peer Recovery is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT04925427 reports 5 study locations spanning 1 distinct geographic area — top geographies include Illinois. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT04925427 about?
NCT04925427 is a clinical study titled "Reducing Opioid Mortality in Illinois". Reducing Opioid Mortality in Illinois (ROMI) is 5-year research study led by the University of Chicago in partnership with the University of Illinois at Chicago's (UIC) Community Outreach Intervention Projects (COIP), the Illinois Criminal Justice Information Authority (ICJIA) and the American Insti...
What is the current status of trial NCT04925427?
This trial is currently recruiting. It is a NA study. The enrollment target is 1,500 participants. The study started on 2021-08-10. Estimated completion is 2026-08-30.
What conditions does trial NCT04925427 study?
This clinical trial studies the following conditions: Opioid Use, Opioid-use Disorder. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT04925427?
The interventions under investigation include: Case Management and Peer Recovery (BEHAVIORAL), Naloxone-Only (BEHAVIORAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT04925427?
This trial is sponsored by University of Chicago, which has 846 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT04925427 being conducted?
This trial has 5 study locations across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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