Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04479072 · ClinicalTrials.gov registry record · Phase 4
Aspirin and Preeclampsia
A Phase 4 study of Preeclampsia Postpartum, sponsored by University of Chicago.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 180
- Enrollment target
- 1
- Study location
NCT04479072: Recruiting Phase 4 study of Preeclampsia Postpartum, sponsored by University of Chicago.
NCT04479072 is a Phase 4 study of Preeclampsia Postpartum that is actively recruiting participants, run by University of Chicago. The registered enrollment target is 180 participants, above the 52-participant average among 8 other Preeclampsia Postpartum trials with a reported enrollment target (246% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04479072, a Phase 4 study of Preeclampsia Postpartum, is actively recruiting participants, sponsored by University of Chicago.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 180 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a single-center, double-blind, randomized, placebo-controlled clinical trial. Peripartum and postpartum Activin A are significantly elevated in women with preeclampsia. Our hypothesis is that elevated Activin A levels reflect a remediable signal and that reducing postpartum Activin A levels with aspirin therapy will improve (GLS) in preeclamptic patients.
Primary Outcome
The primary outcome will compare Activin A levels at 6 months between patients randomized to aspirin therapy versus placebo and the observational group.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Aspirin 81 mg
Study Locations (1)
Illinois
- University of Chicago Hospital - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 180 participants |
| Start Date | 2021-02-15 |
| Est. Completion | 2026-12-31 |
| Phase | Phase 4 |
What NCT04479072 shows while recruiting
NCT04479072 is an interventional study that assigns participants to a tested intervention. The registered 180 participants enrollment target is mid-sized for trials with a published cap, above the 52-participant average among 8 other Preeclampsia Postpartum trials with a reported enrollment target (246% higher).
The record links to 1 condition, with Preeclampsia Postpartum appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT04479072 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT04479072 about?
NCT04479072 is a clinical study titled "Aspirin and Preeclampsia". This is a single-center, double-blind, randomized, placebo-controlled clinical trial. Peripartum and postpartum Activin A are significantly elevated in women with preeclampsia. Our hypothesis is that elevated Activin A levels reflect a remediable signal and that reducing postpartum Activin A levels ...
What is the current status of trial NCT04479072?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 180 participants. The study started on 2021-02-15. Estimated completion is 2026-12-31.
What conditions does trial NCT04479072 study?
This clinical trial studies the following conditions: Preeclampsia Postpartum.
What interventions are being tested in trial NCT04479072?
The interventions under investigation include: Placebo (DRUG), Aspirin 81 mg (DRUG).
Who is sponsoring clinical trial NCT04479072?
This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04479072 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Preeclampsia Postpartum
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04479072's enrollment target sits among peer trials
180 1st of 8 higher than 8 of 8 other Preeclampsia Postpartum trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Preeclampsia Postpartum trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Aspirin for Postpartum Patients With Preeclampsia
RECRUITING · Phase 2
-
Postpartum Low-Dose Aspirin and Preeclampsia
RECRUITING · Phase 2
-
Sensitivity of Angiotensin II Type II Receptors in Women Following Preeclampsia
RECRUITING · Early Phase 1
-
Vascular Effects of High-Salt After Preeclampsia
RECRUITING · Early Phase 1
-
Preeclampsia Educational Program Study (PrEPS)
ACTIVE NOT RECRUITING · NA
-
MR and Inflammation After Preeclampsia
ACTIVE NOT RECRUITING · Early Phase 1
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01558804 · 180 participants
GRoup A StrePtococcus
- NCT02932176 · 180 participants
Machine Learning for Handheld Vascular Studies
- NCT03384563 · 180 participants · Phase 4
Effect of Dexmedetomidine on the Minimum Alveolar Concentration of Sevoflurane
- NCT03423628 · 180 participants · Phase 1
A Study to Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI