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NCT05104710 · ClinicalTrials.gov registry record

Intermuscular Coherence as a Biomarker for ALS

A clinical trial of Amyotrophic Lateral Sclerosis, sponsored by University of Chicago.

Recruiting
Registry status
650
Enrollment target
4
Study locations

NCT05104710 is a study of Amyotrophic Lateral Sclerosis that is actively recruiting participants, run by University of Chicago. The registered enrollment target is 650 participants, below the 892-participant average among 102 other Amyotrophic Lateral Sclerosis trials with a reported enrollment target (27% lower). The trial reports 4 study locations across 4 states.

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The verdict

NCT05104710, a study of Amyotrophic Lateral Sclerosis, is actively recruiting participants, sponsored by University of Chicago.

RECRUITING
Registry status
650 participants
Enrollment target
4
Study locations

Study Summary

The specific aims of this study are to: 1. Determine if a painless and quick measurement of muscle activity using surface electrodes can help with the diagnosis of ALS. Specifically, we ask if a measure of intermuscular coherence (IMC-βγ), when added to current diagnostic criteria (Awaji criteria), can differentiate ALS from mimic diseases more accurately and earlier than currently possible. 2. Characterize IMC-βγ in neurotypical subjects by age, sex, race, and ethnicity. 3. Follow a cohort of ALS patients longitudinally to determine if IMC-βγ changes with ALS disease progression and whether such changes correlate with functional and clinical scores, or survival.

Conditions Studied

Amyotrophic Lateral Sclerosis

Study Locations (4)

California

  • University of California Center for Clinical Research - Irvine

Florida

  • University of Miami Miller School of Medicine - Miami

Massachusetts

  • Massachusetts General Hospital - Boston

Missouri

  • Washington University Medical Center - St Louis

Trial Details

FieldValue
Enrollment Target 650 participants
Start Date 2021-03-31
Est. Completion 2026-12-31

Sponsor

University of Chicago

796 total trials

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What the Registry Record Tells You About NCT05104710

The ClinicalTrials.gov registry entry for NCT05104710 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 650 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 892-participant average among 102 other Amyotrophic Lateral Sclerosis trials with a reported enrollment target (27% lower). The listed sponsor is University of Chicago, which has 796 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Amyotrophic Lateral Sclerosis appearing as the primary indexed condition, and to 0 interventions.

NCT05104710 reports 4 study locations spanning 4 distinct geographic areas - top geographies include California, Florida, Massachusetts.

Frequently Asked Questions

What is clinical trial NCT05104710 about?

NCT05104710 is a clinical study titled "Intermuscular Coherence as a Biomarker for ALS". The specific aims of this study are to: 1. Determine if a painless and quick measurement of muscle activity using surface electrodes can help with the diagnosis of ALS. Specifically, we ask if a measure of intermuscular coherence (IMC-βγ), when added to current diagnostic criteria (Awaji criteria),...

What is the current status of trial NCT05104710?

This trial is currently recruiting. The enrollment target is 650 participants. The study started on 2021-03-31. Estimated completion is 2026-12-31.

What conditions does trial NCT05104710 study?

This clinical trial studies the following conditions: Amyotrophic Lateral Sclerosis.

Who is sponsoring clinical trial NCT05104710?

This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05104710 being conducted?

This trial has 4 study locations across California, Florida, Massachusetts, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.