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NCT04515836 · ClinicalTrials.gov registry record · Phase 2

Olaparib in Patients With HRD Malignant Mesothelioma

A Phase 2 study of Mesothelioma and Homologous Recombination Deficiency, sponsored by University of Chicago.

Recruiting
Registry status
Phase 2
Development phase
56
Enrollment target
1
Study location

NCT04515836 is a Phase 2 study of Mesothelioma and Homologous Recombination Deficiency that is actively recruiting participants, run by University of Chicago. The registered enrollment target is 56 participants, below the 197-participant average among 46 other Mesothelioma trials with a reported enrollment target (72% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04515836, a Phase 2 study of Mesothelioma and Homologous Recombination Deficiency, is actively recruiting participants, sponsored by University of Chicago.

RECRUITING
Registry status
Phase 2
Development phase
56 participants
Enrollment target
1
Study location

Study Summary

In this study, researchers will give olaparib (a drug) to mesothelioma patients who have specific changes in their DNA (known as gene mutations). Researchers will give this drug to each patient on the study to find out if it will help the patient's tumor shrink or stop growing.

Interventions

  • DRUG Olaparib

Study Locations (1)

Illinois

  • University of Chicago Medical Center - Chicago

Trial Details

FieldValue
Enrollment Target 56 participants
Start Date 2021-02-19
Est. Completion 2028-04-15
Phase Phase 2

Sponsor

University of Chicago

796 total trials

What the Registry Record Tells You About NCT04515836

The ClinicalTrials.gov registry entry for NCT04515836 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 56 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 197-participant average among 46 other Mesothelioma trials with a reported enrollment target (72% lower). The listed sponsor is University of Chicago, which has 796 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Mesothelioma appearing as the primary indexed condition, and to 1 intervention - of which Olaparib is the first listed.

NCT04515836 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.

Frequently Asked Questions

What is clinical trial NCT04515836 about?

NCT04515836 is a clinical study titled "Olaparib in Patients With HRD Malignant Mesothelioma". In this study, researchers will give olaparib (a drug) to mesothelioma patients who have specific changes in their DNA (known as gene mutations). Researchers will give this drug to each patient on the study to find out if it will help the patient's tumor shrink or stop growing.

What is the current status of trial NCT04515836?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 56 participants. The study started on 2021-02-19. Estimated completion is 2028-04-15.

What conditions does trial NCT04515836 study?

This clinical trial studies the following conditions: Mesothelioma, Homologous Recombination Deficiency.

What interventions are being tested in trial NCT04515836?

The interventions under investigation include: Olaparib (DRUG).

Who is sponsoring clinical trial NCT04515836?

This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04515836 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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