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NCT03571321 · ClinicalTrials.gov registry record · Phase 1
Ruxolitinib and Chemotherapy in Adolescents and Young Adults With Ph-like Acute Lymphoblastic Leukemia
A Phase 1 study of Acute Lymphoblastic Leukemia and ALL, sponsored by University of Chicago.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 15
- Enrollment target
- 1
- Study location
NCT03571321: Recruiting Phase 1 study of Acute Lymphoblastic Leukemia and ALL, sponsored by University of Chicago.
NCT03571321 is a Phase 1 study of Acute Lymphoblastic Leukemia and ALL that is actively recruiting participants, run by University of Chicago. The registered enrollment target is 15 participants, below the 382-participant average among 131 other Acute Lymphoblastic Leukemia trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03571321, a Phase 1 study of Acute Lymphoblastic Leukemia and ALL, is actively recruiting participants, sponsored by University of Chicago.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 15 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will test if adding ruxolitinib to standard multi-drug chemotherapy regimen will be safe and tolerated in adolescents and young adults with newly diagnosed Ph-like acute lymphoblastic leukemia (ALL).
Primary Outcome
Determined by rate of side effects seen when combination is given
Conditions Studied
Interventions
- DRUG Cyclophosphamide
- DRUG Vincristine
- DRUG Ruxolitinib
- DRUG Cytarabine
- DRUG Mercaptopurine
Study Locations (1)
Illinois
- University of Chicago Medical Center - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2019-05-28 |
| Est. Completion | 2027-09-05 |
| Phase | Phase 1 |
What NCT03571321 shows while recruiting
NCT03571321 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 382-participant average among 131 other Acute Lymphoblastic Leukemia trials with a reported enrollment target (96% lower).
The record links to 3 conditions, with Acute Lymphoblastic Leukemia appearing as the primary indexed condition, and to 5 interventions - of which Cyclophosphamide is the first listed.
NCT03571321 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT03571321 about?
NCT03571321 is a clinical study titled "Ruxolitinib and Chemotherapy in Adolescents and Young Adults With Ph-like Acute Lymphoblastic Leukemia". This study will test if adding ruxolitinib to standard multi-drug chemotherapy regimen will be safe and tolerated in adolescents and young adults with newly diagnosed Ph-like acute lymphoblastic leukemia (ALL).
What is the current status of trial NCT03571321?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 15 participants. The study started on 2019-05-28. Estimated completion is 2027-09-05.
What conditions does trial NCT03571321 study?
This clinical trial studies the following conditions: Acute Lymphoblastic Leukemia, ALL, ALL, Childhood.
What interventions are being tested in trial NCT03571321?
The interventions under investigation include: Cyclophosphamide (DRUG), Vincristine (DRUG), Ruxolitinib (DRUG), Cytarabine (DRUG), Mercaptopurine (DRUG).
Who is sponsoring clinical trial NCT03571321?
This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03571321 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Acute Lymphoblastic Leukemia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03571321's enrollment target sits among peer trials
15 114th of 131 higher than 14 of 131 other Acute Lymphoblastic Leukemia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Acute Lymphoblastic Leukemia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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