St. Jude Children's Research Hospital

410 total trials 90 currently recruiting 227 completed

St. Jude Children's Research Hospital sponsors 410 registered US clinical trials on ClinicalTrials.gov, 90 of them currently recruiting, and 227 completed. 19 of these trials are in Phase 3-4 (later-stage) and 173 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Sickle Cell Disease, with 17 trials.

Trial Pipeline

410 total, page 8 of 9

COMPLETED Phase 1

Haploidentical Stem Cell Transplant for Patients With Sickle Cell Disease and Prior Stroke or Abnormal Transcranial Ultrasound

NCT00152113

COMPLETED

Rasburicase Treatment for Chemotherapy or Malignancy-Induced Hyperuricemia in Asthma/Allergy Patients

NCT00186940

COMPLETED Phase 1

Erlotinib and Radiation Therapy in Treating Young Patients With Newly Diagnosed Glioma

NCT00124657

COMPLETED Phase 1

Evaluate Tolerability of a Recombinant DNA HIV-1 Vaccine in Healthy Adults

NCT00187148

COMPLETED Phase 1

Irinotecan, Vincristine, and Dexamethasone In Children With Relapsed And/Or Refractory Hematologic Malignancies

NCT00718757

TERMINATED

Study of Stored Tumor Samples in Young Patients With Brain Tumors

NCT00897286

COMPLETED Phase 1

Use of Hydroxyurea and Magnesium Pidolate for Treatment of Sickle Cell Disease

NCT00143572

COMPLETED Phase 1

Everolimus for Treating Pediatric Patients With Recurrent or Refractory Tumors

NCT00187174

TERMINATED NA

Stem Cell Transplantation for Children Affected With Osteopetrosis

NCT00145587

COMPLETED Phase 2

HLA-Nonidentical Stem Cell and Natural Killer Cell Transplantation for Children Less the Two Years of Age With Hematologic Malignancies

NCT00145626

TERMINATED Phase 2

Trial of Oral Glutamine in Patients With Sickle Cell Anemia

NCT00131508

COMPLETED NA

Marrow Mesenchymal Cell Therapy for Osteogenesis Imperfecta: A Pilot Study

NCT00187018

COMPLETED Phase 1

Transplantation of Hematopoietic Cells in Children With Severe Combined Immunodeficiency Syndrome

NCT00152100

COMPLETED NA

Family-Staff Communication Intervention at the Time of Difficult Treatment Decision Making

NCT00827437

COMPLETED Phase 2

Therapy for Pediatric Relapsed or Refractory Acute Lymphoblastic Leukemia

NCT00186875

COMPLETED

Pilot Test for a Newly Developed Nutrition Screening Method: Pediatric Subjective Global Assessment

NCT00665691

COMPLETED Phase 1

Prevention of Diarrhea in Patients Taking IV Irinotecan for Relapsed or Difficult to Treat Pediatric Solid Tumors

NCT00143533

COMPLETED Phase 3

Treatment of Patients With Newly Diagnosed Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Atypical Teratoid Rhabdoid Tumor

NCT00085202

COMPLETED NA

Chemotherapy With CD133+ Select Autologous Hematopoietic Stem Cells for Children With Solid Tumors and Lymphomas

NCT00152126

COMPLETED Phase 2

Haploidentical Stem Cell Transplant for Treatment Refractory Hematological Malignancies

NCT00145613

COMPLETED Phase 1

Study of ZD1839 Combined With Irinotecan and Vincristine in Pediatric Patients With Refractory Solid Tumors

NCT00186979

COMPLETED NA

Testing the Effectiveness of Child and Parent-Targeted Health Promotion Interventions in Pediatric Stem Cell Transplantation

NCT00760227

COMPLETED Phase 1

Radiofrequency Ablation of Tumors

NCT00705497

COMPLETED NA

Purified CD34+ Hematopoietic Stem Cell Transplantation From Alternate Donors for Patients With Severe Aplastic Anemia

NCT00186797

COMPLETED Phase 2

A Phase II Study of Topotecan in Children With Recurrent Wilms Tumor

NCT00187031

COMPLETED NA

Reduction of Environmental Tobacco Smoke (ETS) Exposure In Pediatric Cancer Patients

NCT00766766

COMPLETED NA

Study for Treatment of Cancer in Children With Ataxia-telangiectasia

NCT00187057

COMPLETED Phase 3

Treatment of Patients With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplasia

NCT00136084

COMPLETED Phase 1

Determination of a Safe Dose of Optison in Pediatric Patients With Solid Tumors

NCT00186953

COMPLETED Phase 3

Stem Cell Transplantation for Patients With Hematologic Malignancies

NCT00152139

COMPLETED Phase 3

Haploidentical Stem Cell Transplantation for Patients With Hematologic Malignancies

NCT00186823

TERMINATED Phase 3

Study of Fentanyl-Propofol-EMLA of L.M.X4 Technique for Bone Marrow Aspiration

NCT00187135

COMPLETED

AVN of Weight-Bearing Joints In Patients With Hematologic Malignancies Treated With Dexamethasone Or Prednisone

NCT00719147

COMPLETED Phase 3

Therapy for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia

NCT00137111

COMPLETED Phase 3

A Severity-Adapted Clinical Trial of Diminished Bone Mineral Density in Acute Lymphoblastic Leukemia Survivors

NCT00186901

COMPLETED Phase 1

Recombinant Human Thrombopoietin in Children Receiving Ifosfamide, Carboplatin, and Etoposide Chemotherapy

NCT00187109

COMPLETED Phase 1

Oxaliplatin in Treating Children With Advanced Solid Tumors

NCT00005844

COMPLETED Phase 2

Therapy for Pediatric Hodgkin Lymphoma

NCT00145600

COMPLETED Phase 4

Learning Impairments Among Survivors of Childhood Cancer

NCT00576472

COMPLETED Phase 1

Stromal Therapy of Osteodysplasia After Allogeneic Bone Marrow Transplantation

NCT00186914

COMPLETED Phase 2

Osteosarcoma1999-A Study Of Intensive Chemotherapy for Osteosarcoma

NCT00145639

COMPLETED Phase 2

Irinotecan Followed by Radiation Therapy and Temozolomide in Treating Children With Newly Diagnosed Brain Tumor

NCT00004068

COMPLETED Phase 2

Irinotecan Followed By Fluorouracil and Leucovorin in Treating Patients With Stage III or Stage IV Colorectal Carcinoma (Cancer), Other Refractory Carcinoma, or Metastatic Adenoma (Cancer) of Unknown Primary Origin

NCT00004005

COMPLETED Phase 1

Gene Modified Allogeneic Neuroblastoma Cells For Treatment of Relapsed/Refractory Neuroblastoma

NCT00186862

TERMINATED Phase 3

Total Therapy Study XIV for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia

NCT00187005

COMPLETED NA

Large Cell Lymphoma Pilot Study III

NCT00187070

COMPLETED Phase 2

Combination Chemotherapy, Radiation Therapy, and Bone Marrow Transplantation in Treating Patients With Retinoblastoma

NCT00004006

COMPLETED Phase 1

Evaluation of the Safety of a Polyvalent Virus in Healthy Adults

NCT00187044

COMPLETED Phase 2

Therapy for Children With Advanced Stage High Risk Neuroblastoma

NCT00186849

COMPLETED Phase 2

A Study for Image-Guided Radiation Therapy in Pediatric Brain Tumors and Side Effects

NCT00187226

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Phase Distribution

PhaseTrial count
Phase 1 87
Phase 2 86
Phase 3 17
Phase 4 2

What the Pipeline for St. Jude Children's Research Hospital Shows

According to the ClinicalTrials.gov registry, St. Jude Children's Research Hospital is linked to 410 US clinical trials across every stage of research activity. Of those, 90 studies are currently recruiting, about 22% of the sponsor's indexed portfolio, and 227 are already marked complete, representing roughly 55% of the total.

The phase mix for St. Jude Children's Research Hospital reports 19 late-stage studies (Phase 3 and Phase 4 combined) and 173 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for St. Jude Children's Research Hospital is Sickle Cell Disease with 17 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.