Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 104 recruiting now official registry

Solid Tumor clinical trials

Every US clinical trial registered for Solid Tumor — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

197 US clinical trials · 104 currently recruiting

The research picture

Solid Tumor has 197 registered US clinical trials, 104 of them open to new participants right now — about 53% of the total.

104
recruiting participants now
53%
of trials open to enrollment
4
in Phase 3–4 (later-stage)
11
top sponsor: Memorial Sloan Kettering Cancer Center

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 10,000 participants

Natural History and Biospecimen Acquisition for Children and Adults With Rare Solid Tumors

National Cancer Institute (NCI)

NCT03739827

RECRUITING 5,000 participants

Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies

Children's Oncology Group

NCT00736749

RECRUITING 3,644 participants

Remote Digital Physiologic Data Collection in Cancer: An MSK Registry Protocol

Memorial Sloan Kettering Cancer Center

NCT05390827

RECRUITING Phase 1 1,314 participants

Study of Zanzalintinib in Combination With Immuno-Oncology Agents in Participants With Solid Tumors

Exelixis

NCT05176483

RECRUITING Phase 1 681 participants

A Study of ASP3082 in Adults With Advanced Solid Tumors

Astellas Pharma

NCT05382559

RECRUITING Phase 1 575 participants

FOG-001 in Locally Advanced or Metastatic Solid Tumors

Parabilis Medicines

NCT05919264

RECRUITING Phase 1 542 participants

A First-in-human, Dose Escalation and Dose Expansion Study of SAR445877 in Adult Participants With Advanced Solid Tumors

Sanofi

NCT05584670

RECRUITING Phase 1 500 participants

A Phase 1/2 Study of BHV-1510 (Previously PBI-410) in Advanced Solid Tumors

Biohaven Therapeutics

NCT06384807

RECRUITING Phase 1 410 participants

A Study to Evaluate Safety, Pharmacokinetics, and Activity of GDC-7035 as a Single Agent and in Combination in Patients With Advanced Solid Tumors

Genentech

NCT06619587

RECRUITING 400 participants

The Intersection of Oncology Care and Worker Well-Being

University of Colorado, Denver

NCT05250284

RECRUITING Phase 1 370 participants

A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)

Merck Sharp & Dohme

NCT02332668

RECRUITING Phase 1 364 participants

A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors

Astellas Pharma

NCT07094204

RECRUITING Phase 1 336 participants

Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion

Bristol-Myers Squibb

NCT05245500

RECRUITING Phase 1 332 participants

A Study of JZP815 Oral Capsules in Adult Participants With Advanced or Metastatic Solid Tumors Harboring Mitogen Activated Protein Kinase (MAPK) Pathway Alterations to Investigate the Safety, Dosing, and Antitumor Activity of JZP815

Jazz Pharmaceuticals

NCT05557045

RECRUITING Phase 1 330 participants

A Study of PYX-201 in Advanced Solid Tumors

Pyxis Oncology

NCT05720117

RECRUITING Phase 1 330 participants

Study of TJ033721 (Givastomig) in Subjects With Advanced or Metastatic Solid Tumors

I-Mab Biopharma US Limited

NCT04900818

RECRUITING Phase 1 316 participants

Phase 1a and Phase 2 Study for Safety, Preliminary Efficacy, PK and PD of ST-067

Simcha IL-18

NCT04787042

RECRUITING NA 285 participants

Psychotherapy Intervention for Latinos With Adv Cancer

Memorial Sloan Kettering Cancer Center

NCT04537936

RECRUITING Phase 1 263 participants

A Study of CUSP06 in Patients With Platinum-Refractory/Resistant Ovarian Cancer and Other Advanced Solid Tumors

OnCusp Therapeutics

NCT06234423

RECRUITING NA 234 participants

Adapting for Latinx Populations an Intervention That Involves Discussing and Sharing Patients' Health-Related Values

Memorial Sloan Kettering Cancer Center

NCT04942717

RECRUITING Phase 1 232 participants

A Study of SPX-303, a Bispecific Antibody Targeting LILRB2 and PD-L1 in Patients With Solid Tumors

SparX Biotech(Jiangsu) Co.

NCT06259552

RECRUITING Phase 1 230 participants

Indocyanine Green (ICG) Guided Tumor Resection

St. Jude Children's Research Hospital

NCT04084067

RECRUITING Phase 1 222 participants

A Study of 177Lu-FAP-2286 in Advanced Solid Tumors

Novartis Pharmaceuticals

NCT04939610

RECRUITING Phase 1 220 participants

A Study to Assess IPN01194 When Administered Alone in Adults With Advanced Solid Tumours

Ipsen

NCT06305247

RECRUITING Phase 1 219 participants

A Phase I Study of ROSE12 Alone and in Combination With Other Anti-tumor Agents in Patients With Solid Tumors

Chugai Pharmaceutical

NCT05907980

RECRUITING Phase 1 217 participants

A Study Investigating BGB-26808 Alone or in Combination With Tislelizumab in Participants With Advanced Solid Tumors

BeOne Medicines

NCT05981703

RECRUITING Phase 1 205 participants

A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

Terremoto Biosciences

NCT07109726

RECRUITING Phase 2 200 participants

Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors

Memorial Sloan Kettering Cancer Center

NCT04165772

RECRUITING Phase 1 200 participants

Safety and Preliminary Efficacy of OBT076 in Recurrent/Metastatic CD205+ Solid Tumors

Oxford BioTherapeutics

NCT04064359

RECRUITING Phase 1 195 participants

A Study of PT0511 in Participants With KRAS Mutated or Amplified Advanced Solid Tumors

PAQ Therapeutics

NCT07300150

RECRUITING Phase 1 191 participants

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

Tango Therapeutics

NCT06810544

RECRUITING NA 190 participants

Psychotherapy Intervention for Latinos With Advanced Cancer

Memorial Sloan Kettering Cancer Center

NCT04015609

RECRUITING Phase 1 188 participants

STC-15 as a Part of Combination Therapy With Toripalimab in Selected Advanced Cancers

STORM Therapeutics

NCT06975293

RECRUITING Phase 1 182 participants

A Study to Evaluate the Safety, Tolerability, and Efficacy of MORAb-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (FRα)-Targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types

Eisai

NCT04300556

RECRUITING Phase 2 180 participants

Givastomig Combined With Nivolumab and Chemotherapy in Adults With CLDN18.2 Positive Metastatic Gastric Cancer (GIVA-2)

I-Mab Biopharma US Limited

NCT07432295

RECRUITING Phase 1 180 participants

Study of IDE397 in Participants With Solid Tumors Harboring MTAP Deletion

IDEAYA Biosciences

NCT04794699

RECRUITING Phase 1 161 participants

A Phase 1/2, Open-label, Multicenter, FIH Study to Evaluate Safety, Tolerability, PK and Anti-tumor Activity of YH42946

Yuhan Corporation

NCT06616766

RECRUITING NA 160 participants

Implementation of an Oral Chemotherapy Adherence Intervention

UNC Lineberger Comprehensive Cancer Center

NCT06989489

RECRUITING Phase 1 156 participants

First-in-human Study of CRB-601-01 to Treat Patients With Advanced Solid Tumor.

Corbus Pharmaceuticals

NCT06603844

RECRUITING Phase 1 150 participants

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

NiKang Therapeutics

NCT06586957

RECRUITING 150 participants

Liquid Biopsy-informed Precision Oncology Study to Evaluate Utility of Plasma Genomic Profiling for Therapy Selection

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT05585684

RECRUITING Phase 1 150 participants

Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer

Incyclix Bio

NCT05735080

RECRUITING Phase 1 150 participants

A First-in-Human Study of SON-DP in Participants With Relapsed/Refractory Intolerant to Standard of Care Therapies for Advanced/Metastatic Solid Tumors

Qurgen

NCT05989724

RECRUITING Phase 1 140 participants

FIH Trial of VERT-002 in Patients With Locally Advanced or Metastatic Solid Tumors With MET Alterations

Pierre Fabre Medicament

NCT06669117

RECRUITING Phase 1 140 participants

A Study of ZN-c3 in Patients With Ovarian Cancer

K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals

NCT04516447

RECRUITING Phase 1 140 participants

Study of TU2218 in Combination With KEYTRUDA®(Pembrolizumab) in Patients With Advanced Solid Tumors

TiumBio Co.

NCT05784688

RECRUITING Phase 1 128 participants

Phase Ib Study of CBP-1019 in Combination With FOLFOX +/- Bevacizumab, Pembrolizumab, or Enzalutamide for Metastatic TRPV6-overexpressing Solid Tumors of Epithelial Origin

M.D. Anderson Cancer Center

NCT06576037

RECRUITING NA 125 participants

DESCANSO, a Mental Health Intervention for Depression, Insomnia, and Fatigue Symptoms in Latino People With Cancer

Memorial Sloan Kettering Cancer Center

NCT07225088

RECRUITING 120 participants

Characterizing Sleep Among Long-term Survivors of Childhood Cancer

St. Jude Children's Research Hospital

NCT05480904

RECRUITING NA 120 participants

High Dose Re-Irradiation Utilizing Advanced Deformable Image Registration (DIR) and Individualized Organ At Risk (OAR) Dose Calculations With Organ Specific Toxicity Analysis

Medical College of Wisconsin

NCT05301101

RECRUITING Phase 1 120 participants

SMP-3124LP in Adults With Advanced Solid Tumors

Sumitomo Pharma America

NCT06526819

RECRUITING Phase 1 117 participants

Safety and Tolerability Study of GIM-531 in Advanced Solid Tumors

Georgiamune

NCT06425926

RECRUITING Phase 1 115 participants

A Study of PT0253 in Participants With KRAS G12D Mutated Advanced Solid Tumors

PAQ Therapeutics

NCT06797336

RECRUITING Phase 1 110 participants

A Study to Evaluate Safety, Efficacy, and Pharmacokinetics in Participants With Advanced Solid Tumors

Eutilex

NCT04903873

RECRUITING Phase 1 105 participants

Study to Evaluate IMGS-001 Treatment in Patients With Relapsed or Refractory Advanced Solid Tumors

ImmunoGenesis

NCT06014502

RECRUITING Phase 1 103 participants

A Study of BGC515 Capsules in Subjects With Advanced Solid Tumors

BridGene Biosciences

NCT06452160

RECRUITING Phase 4 100 participants

Dabrafenib and/or Trametinib Rollover Study

Novartis Pharmaceuticals

NCT03340506

RECRUITING 100 participants

A Pilot Prospective Clinical Trial Using Remote Monitoring for Cancer Patients Undergoing Outpatient Chemotherapy

Inova Health Care Services

NCT06106360

RECRUITING 100 participants

Prospective Evaluation Of Delayed Effects Of Pediatric Car T Cell Therapy

St. Jude Children's Research Hospital

NCT06579469

RECRUITING Phase 1 97 participants

Phase I Study of Tolododekin Alfa (ANK-101) in Advanced Solid Tumors

Ankyra Therapeutics

NCT06171750

RECRUITING Phase 1 95 participants

A Phase 1 Study of BHV-1530 in Advanced Solid Tumors

Biohaven Therapeutics

NCT06874335

RECRUITING Phase 1 85 participants

A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABSK061 in Patients With Advanced Solid Tumors

Abbisko Therapeutics Co

NCT05244551

RECRUITING Phase 1 85 participants

Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmocodynamics and Preliminary Antitumor Activity of AT-1965 in Patients With Advanced, Refractory or Recurrent Solid Tumors

Alyssum Therapeutics

NCT06234098

RECRUITING Phase 1 83 participants

FIH Study to Evaluate Safety, Tolerability, PK, PD & Preliminary Efficacy of AT03-65 With Advanced Solid Tumors

Axcynsis Therapeutics Pte

NCT06809114

RECRUITING Phase 1 75 participants

A Study of XB628 in Participants With Recurrent Advanced or Metastatic Solid Tumors

Exelixis

NCT06952010

RECRUITING Phase 1 70 participants

Study of STP938 in Advanced Solid Tumours

Step Pharma, SAS

NCT06297525

RECRUITING Phase 1 70 participants

Safety and Preliminary Efficacy of SA53-OS in Patients With Locally Advanced or Metastatic Solid Tumors

Lamassu Bio

NCT06578624

RECRUITING Phase 1 61 participants

Study to Evaluate IMP9064 as a Monotherapy or in Combination in Patients With Advanced Solid Tumors

Impact Therapeutics

NCT05269316

RECRUITING Phase 2 60 participants

A Study to Evaluate the Efficacy and Safety of TL118 in Solid Tumors Patients

Teligene US

NCT06010342

RECRUITING NA 60 participants

Let's Get REAL: Family Health Communication Tool in Pediatric Stem Cell Transplant and Cellular Therapy

Washington University School of Medicine

NCT06689800

RECRUITING Phase 1 56 participants

Imaging of Solid Tumors Using 18F-TRX

Rahul Aggarwal

NCT06942104

RECRUITING Phase 2 55 participants

A Phase 2 Study of Avutometinib (VS-6766) Plus Defactinib

University of Oklahoma

NCT05512208

RECRUITING Phase 2 55 participants

Sirolimus in Combination With Metronomic Chemotherapy in Children With High-Risk Solid Tumors

Emory University

NCT04469530

RECRUITING Phase 1 54 participants

Trial to Evaluate Safety, PD & PK of IV Study Drug, QN-302, in Pts w/ Advanced or Metastatic Solid Tumors

Qualigen Theraputics

NCT06086522

RECRUITING Phase 3 50 participants

An Extension Study for Patients Previously Enrolled in Studies With Pelabresib

Novartis Pharmaceuticals

NCT06401356

RECRUITING Phase 1 50 participants

BP1001-A in Patients With Advanced or Recurrent Solid Tumors

Bio-Path Holdings

NCT04196257

RECRUITING Phase 1 48 participants

SB-4826 in Adult Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin Lymphomas

University of California, San Diego

NCT07222631

RECRUITING Phase 2 45 participants

A Study of Selinexor in People With Wilms Tumors and Other Solid Tumors

Memorial Sloan Kettering Cancer Center

NCT05985161

RECRUITING Phase 1 45 participants

Binary Oncolytic Adenovirus in Combination With HER2-Specific Autologous CAR VST, Advanced HER2 Positive Solid Tumors

Baylor College of Medicine

NCT03740256

RECRUITING Phase 1 40 participants

MEM-288 Oncolytic Virus Alone and in Combination With Standard of Care Therapy in Advanced Solid Tumors

Memgen

NCT05076760

RECRUITING Phase 1 40 participants

Safety and Anti-Tumor Activity of TYRA-200 in Advanced Cholangiocarcinoma With Activating FGFR2 Gene Alterations

Tyra Biosciences

NCT06160752

RECRUITING Phase 1 37 participants

RAPA-201 Therapy of Solid Tumors

Rapa Therapeutics

NCT05144698

RECRUITING Phase 1 36 participants

Phase 1b Trial of BMS-986504 in Combination With Olaparib in Patients With MTAP Loss

M.D. Anderson Cancer Center

NCT07382544

RECRUITING Phase 1 36 participants

Multi Tumor-Associated Antigen-Specific T Lymphocytes to Treat Patients With High Risk Solid Tumors

Children's National Research Institute

NCT05238792

RECRUITING Phase 1 35 participants

Phase 1 Dose Escalation and Dose Expansion Trial of NP-101 in Patients With Solid Tumors

M.D. Anderson Cancer Center

NCT06563375

RECRUITING Phase 1 33 participants

R-5780-01 In Combination With PD-1 Checkpoint Inhibitors (Checkpoint Protein on Immune Cells Called T Cells) in Patients With Solid Tumors

Rise Therapeutics

NCT06398418

RECRUITING Phase 1 32 participants

Concurrent Azeliragon With Craniospinal Irradiation

NYU Langone Health

NCT06724926

RECRUITING NA 30 participants

Serial Ultrasound of Solid Tumor Lesions to Detect Early Response to Cancer Immunotherapy

Stanford University

NCT05206942

RECRUITING Phase 1 30 participants

A Clinical Study of Intratumoral MVR-T3011 (T3011) Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors

ImmVira Pharma Co.

NCT04370587

RECRUITING 30 participants

Umbilical Cord Blood Transplantation From Unrelated Donors

University of Rochester

NCT03016806

RECRUITING Phase 1 30 participants

Trial of DFP-14927 in Advanced Solid Tumors

Delta-Fly Pharma

NCT03943004

RECRUITING Phase 1 26 participants

A First-in-human (FIH), Phase I Study of PTX-912 in Patients with Locally Advanced/Metastatic Solid Tumors

Proviva Therapeutics

NCT06190886

RECRUITING Phase 1 25 participants

Trial to Evaluate the Safety & Tolerability of JBZ-001 in Pts With Advanced Solid and Hematological Malignancies

Jabez Bioscience

NCT06801002

RECRUITING Early Phase 1 25 participants

Indocyanine Green (ICG) Guided Sentinel Lymph Node Mapping for Pediatric Visceral Solid Tumors

St. Jude Children's Research Hospital

NCT05645523

RECRUITING 24 participants

Ex Vivo Expansion (ACT-X)

Mayo Clinic

NCT07137312

RECRUITING Phase 1 24 participants

NEROFE and Doxorubicin in KRAS-mutated ST2-positive Solid Tumors

Georgetown University

NCT05661201

RECRUITING Phase 1 23 participants

VITAS: Atezolizumab in Combination With Chemotherapy for Pediatric Relapsed/Refractory Solid Tumors

University of Texas Southwestern Medical Center

NCT04796012

RECRUITING Phase 1 21 participants

Study of PAT in Patients With Solid Tumor Cancers

Masonic Cancer Center, University of Minnesota

NCT05338658

RECRUITING Early Phase 1 20 participants

Metronomic Therapy for Pediatric Patients With Solid Tumors at High Risk of Recurrence

Miller Children's & Women's Hospital Long Beach

NCT02446431

RECRUITING Phase 1 20 participants

Phase I Trial to Determine the Dose and Evaluate the PK and Safety of Lutetium Lu 177 Edotreotide Therapy in Pediatric Participants With SSTR-positive Tumors

ITM Solucin

NCT06441331

Phase Distribution

PhaseTrial count
Phase 1 150
Phase 2 15
Phase 3 1
Phase 4 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Solid Tumor Trial Landscape

ClinicalTrials.gov lists 197 US studies indexed under Solid Tumor, and 104 of those are currently open to recruitment — roughly 53% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Solid Tumor shows 4 late-stage studies (Phase 3 and Phase 4 combined) alongside 165 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Solid Tumor is led by Memorial Sloan Kettering Cancer Center with 11 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 100 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Solid Tumor?

PlainTrial tracks 197 US clinical trials for Solid Tumor, of which 104 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Solid Tumor?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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