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NCT00576472 · ClinicalTrials.gov registry record · Phase 4
Learning Impairments Among Survivors of Childhood Cancer
A Phase 4 study, sponsored by St. Jude Children's Research Hospital.
- Completed
- Registry status
- Phase 4
- Development phase
- 469
- Enrollment target
NCT00576472 is a Phase 4 study that has completed, run by St. Jude Children's Research Hospital. The registered enrollment target is 469 participants.
The verdict
NCT00576472, a Phase 4 study, has completed, sponsored by St. Jude Children's Research Hospital.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 469 participants
- Enrollment target
Study Summary
Children surviving some types of cancer have a higher risk of developing learning problems after cancer treatment than do children who have not had cancer or its treatment. Cancer treatment may cause problems with learning, attention, and memory. The purpose of this study is to identify brain changes that may underlie learning problems in cancer survivors and investigate whether methylphenidate (a stimulant medication) may reduce these problems. Subjects who have had treatment for acute lymphoblastic leukemia (ALL) or a brain tumor will be asked to take part in this research study. Siblings of some subjects will also be asked to take part, so that their results can be compared with those of children who have had cancer treatment. We hypothesize that children receiving more aggressive therapy will have lower white matter brain volumes and these volumes will be significantly lower than age-matched siblings. We also hypothesize that children who take methylphenidate will show improvements on teacher and parent report measures of attention and social skills.
Interventions
- DRUG Methylphenidate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 469 participants |
| Start Date | 2000-01 |
| Est. Completion | 2010-03 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00576472
The ClinicalTrials.gov registry entry for NCT00576472 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 469 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is St. Jude Children's Research Hospital, which has 410 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Methylphenidate is the first listed.
NCT00576472 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00576472 about?
NCT00576472 is a clinical study titled "Learning Impairments Among Survivors of Childhood Cancer". Children surviving some types of cancer have a higher risk of developing learning problems after cancer treatment than do children who have not had cancer or its treatment. Cancer treatment may cause problems with learning, attention, and memory. The purpose of this study is to identify brain change...
What is the current status of trial NCT00576472?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 469 participants. The study started on 2000-01. Estimated completion is 2010-03.
What interventions are being tested in trial NCT00576472?
The interventions under investigation include: Methylphenidate (DRUG).
Who is sponsoring clinical trial NCT00576472?
This trial is sponsored by St. Jude Children's Research Hospital, which has 410 total clinical trials registered on ClinicalTrials.gov.
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