Case Comprehensive Cancer Center
Trial Pipeline
Scrambler Therapy for Chemotherapy-Induced Peripheral Neuropathy
NCT07219472
Pulmonary Rehabilitation in Advanced Lung Cancer Survivors
NCT07104630
Trial of Oligometastasis SBRT With Immediate, Simulation-Free Treatment Delivery (OLIGO-SWIFT)
NCT07079098
Musculoskeletal Cancers Remote Monitoring and Care
NCT07129226
Tongue Proactive Strengthening Exercise Program Following Partial/Hemi Glossectomy and Reconstruction
NCT07110142
Trifluridine/Tipiracil + Oxaliplatin in Participants With Advanced or Metastatic Biliary Tract Cancer
NCT07146646
Artificial Intelligence-Powered Support For Quality Of Life Improvement In Participants With Cancer
NCT07167056
Investigation of Impact of AI on Prostate Cancer Workflow
NCT07084779
Prehabilitation for EOC, Fallopian Tube, Primary Peritoneal Carcinoma and Pancreatic Cancer w/ NACT
NCT06412510
Co-Transplant of an Unmodified Haplo-Identical Graft With Cord Blood
NCT06904482
A Phase 2 and Pharmacodynamic Study of Sitagliptin in Patients With Progressive Grade 4 Gliomas
NCT07003542
ECM and Monitoring w/ Alio Smart Patch in Cancer Pts Receiving Chemotherapy
NCT06657183
Cabazitaxel +/- Carboplatin vs 177Lu-PSMA-617 in Metastatic Castrate-resistant Prostate Cancer
NCT06738303
Histotripsy Plus Chemotherapy vs Chemotherapy Alone for Advanced Colorectal Liver Metastasis
NCT07044362
Antibiotic Treatment Effects on Intratumoral Bacteria Modulation in Surgical Patients With Oral Cancer
NCT06627270
Multi-Site Detection of Barrett's Esophagus in Patients Without Chronic GERD Symptoms
NCT06687603
Partial Cystectomy & Extended Pelvic Lymph Node Dissection With SOC Perioperative Systemic Therapy
NCT06290687
Vulvovaginal Graft-versus-Host Disease: Diagnosis and Microbiome Evaluation
NCT06649201
EQUITY GI: A Prospective Study to Enhance Quality, Inclusivity, and Trial Participation in Black Patients With Gastrointestinal Cancer.
NCT06263088
Decreasing Chemotherapy Induced Distress Using Immersive Virtual Reality in Patients With Cancer
NCT06446115
Development of MRF for Characterization of Brain Tumors After Radiotherapy
NCT06101069
Brain MRF in Children, Adolescents and Young Adults With Acute Leukemia
NCT06421155
Metabolic Impact of Prospective Controlled Mediterranean Type Diets on Prostate Cancer
NCT05590624
Linking Somatic Mutation Rate With Baseline Exposure in East Palestine
NCT06357845
Promoting Access, Resources and Treatment Through Novel and Equitable Solutions for Cancer Care
NCT06481774
Fasting During Neoadjuvant Chemotherapy in Patient With Epithelial Ovarian Cancer
NCT06386887
MDRT in Prostate Cancer Treated With Long-term Androgen Deprivation Therapy in the STAMPEDE Trial (METANOVA)
NCT06150417
Nephroureterectomy With and Without Lymph Node Dissection for Upper Tract Urothelial Cell Carcinoma
NCT06262516
Glioblastoma Remote Monitoring and Care - Research Protocol
NCT06129760
Prospective Surgical Study on the Pattern of Electrical Activity in High Grade Glioma as a Predictor of Progression
NCT05565118
Single-Port Transvesical Partial Prostatectomy Versus High Intensity Focused Ultrasound
NCT05610852
Exercise Therapy and Radiation Therapy (EXERT) for Metastatic Prostate Cancer
NCT04556045
Repeat Breast Conserving Surgery Followed by Daily Partial Breast Irradiation in Ipsilateral Breast
NCT06129747
Transplantation of Reconstructed Renal Allografts Following Ex-Vivo Partial Nephrectomy
NCT05725421
Breast Margin Study: Routine Cavity Shave Margins Vs. Selective Margins Using Savi Scout®
NCT05825482
Cleveland African American Prostate Cancer Project
NCT05469269
Unintentional Weight Loss and Cancer: A Prospective Trial of Patient-centered Weight Tracking Combin
NCT05481697
Patient Navigator PRE-ACT Educational Intervention to Promote Decision Making Among Minorities
NCT05701085
Is Intraperitoneal Drainage Necessary Following Distal Pancreatectomy?
NCT05720338
Disulfiram With Copper Gluconate and Liposomal Doxorubicin in Treatment-Refractory Sarcomas
NCT05210374
Methimazole in Patients With Progressive Glioblastoma
NCT05607407
The Utility and Feasibility of Mt-sDNA as a Surveillance Procedure in Colorectal Cancer Survivors
NCT04624555
Alteration of the Immune Microenvironment in Basal Cell Carcinoma Following Photodynamic Therapy
NCT05020912
Genomic Analysis of Families With a History of Discordant Cancers
NCT04860453
Study of Nicotinamide Riboside Supplementation in Allogeneic Hematopoietic Cell Transplantation
NCT04332341
Single- vs. Two-Fraction Spine Stereotactic Radiosurgery for the Treatment of Vertebral Metastases
NCT04218617
Proton Therapy Patient Registry
NCT02986048
Neoadjuvant Radiosurgery for Resectable Brain Metastases: Phase I/II Study
NCT01891318
Abbreviated MBCT for Depression in Older African American/Black Breast Cancer Survivors
NCT06336538
Developing Inclusive Support and Intervention for Spanish-speaking Latiné Prostate Cancer Survivors
NCT06435871
Individualized Treatments in Adults With Relapsed/Refractory Cancers
NCT06024603
Early Detection of Multiple Myeloma to Fight Cancer Disparities: A Screening and Patient Navigation Program
NCT05831358
Ivosidenib + mFOLFIRINOX in Patients With Resectable Pancreatic Adenocarcinoma
NCT05209074
Interventional Program Educates, Identifies + Overcomes Barriers to Complete Screening Mammography
NCT04348123
Low-Dose-Rate Brachytherapy Combined With Immune Checkpoint Inhibition in Cancer
NCT04620603
CPX-351 as a Novel Approach for the Treatment of Older Patients With AML and MDS
NCT04668885
Improving Understanding of Brain Tumors Through Preservation of Biologically Active Brain Tissue
NCT04545177
Targeted Therapy With CDK4/6 Inhibitors in Chemo-Refractory, Rb Wild-Type Extensive SCLC
NCT04010357
Venetoclax in Combination With BEAM Conditioning Regimen for ASCT in Non-Hodgkin Lymphoma
NCT03713580
Ibrutinib With Radiation and Temozolomide in Patients With Newly Diagnosed Glioblastoma
NCT03535350
Ruxolitinib With Radiation and Temozolomide for Grade III Gliomas and Glioblastoma
NCT03514069
Evaluation of an Integrated Imaging System For In Vivo Detection of Fluorescently Labeled Lesions
NCT02802553
Laser Interstitial Thermotherapy (LITT) Combined With Checkpoint Inhibitor for Recurrent GBM (RGBM)
NCT03277638
Transanal Total Mesorectal Excision for Rectal Cancer on Anal Physiology + Fecal Incontinence
NCT03283540
Multi-Parametric Quantitative MR Imaging in Evaluation of Brain Tumors
NCT02956291
Stereotactic Radiosurgery in Treating Patients With Large Brain Metastases
NCT01843413
Effects of Lavender Aromatherapy on Patient Anxiety During Mohs Micrographic Surgery
NCT06167096
A Prospective Study to Evaluate Continuous Positive Airway Pressure Devices to Reduce Pulmonary Dose
NCT05142358
Multidimensional Prehabilitation in Pancreatic Surgery for Pancreatic and Periampullary Neoplasms
NCT05225038
Evaluating the Effectiveness of an Individualized Nutrition and Physical Activity Counseling Program
NCT04365569
Neoadjuvant-Adjuvant Pembrolizumab in Resectable Advanced Basal Cell Carcinoma of H&N
NCT04323202
C-FLASH (Cigarillo Flavor and Abuse Liability, Attention, and Substitution in youtH)
NCT04358705
Leveraging ctDNA Analysis to Improve Early Detection of Cancer Recurrence in the High-Risk Melanoma Setting
NCT05079113
Regorafenib in Bevacizumab Refractory Recurrent Glioblastoma
NCT04051606
Feasibility of a Culturally-Specific Video Text Cessation Intervention With AA Quitline Callers
NCT03927976
Role of Magnetic Resonance Fingerprinting and Quantitative MR Imaging in Breast Cancer
NCT03650803
Osimertinib With Stereotactic Radiosurgery (SRS) in Brain Metastases From EGFR Positive NSCLC
NCT03535363
Improved Intra-operative Safety From Optimal Selection of Anti-slip Surface
NCT03573557
Thiotepa Plus Fludarabine+ Melphalan as the Preparative Regime for Alternative Donor Transplantation
NCT03342196
A Pilot Study of [Ga-68]PSMA PET/MRI for the Assessment of PSMA-positive Tumors
NCT02978586
Music Therapy and Hematopoietic Stem Cell Transplant
NCT03378089
End Nicotine Dependence Clinic
NCT03290430
Pembrolizumab Alone or Sequentially Following Single Fraction Non-ablative Radiation to One of the Target Lesions, in Previously Treated Patients With Stage IV NSCLC
NCT02658097
Optimal Timing of Postoperative Magnetic Resonance Imaging (MRI) in Patients With Extradural Spinal
NCT02790294
Axitinib Given on an Individualized Schedule for Metastatic Renal Cell Cancer
NCT02579811
Treatment of Brain Metastases From Breast Cancer With Eribulin Mesylate
NCT02581839
Hematopoietic Stem Cell Transplant for Sickle Cell Disease
NCT02065596
Targeted Marrow Irradiation, Fludarabine Phosphate, and Busulfan Before Donor Progenitor Cell Transplant in Treating Patients With Hematologic Malignancies
NCT02129582
Dose Monitoring of Busulfan and Combination Chemotherapy in Hodgkin or Non-Hodgkin Lymphoma Undergoing Stem Cell Transplant
NCT01959477
Tailoring Patient Education to Perceived Risk for Falls in Hospitalized Oncology Patients
NCT02081794
Enzalutamide in Patients With High-risk Prostate Cancer
NCT01927627
Feasibility of a Team Approach for Discussing Prognosis and Treatment Goals in Breast Cancer
NCT01876238
Carboplatin, Gemcitabine Hydrochloride, and Stereotactic Body Radiation Therapy in Gynecological Cancer
NCT01652794
Assisted Exercise in Obese Endometrial Cancer Patients
NCT01870947
Methoxyamine and Fludarabine Phosphate in Treating Patients With Relapsed or Refractory Hematologic Malignancies
NCT01658319
Bortezomib, Mitoxantrone, Etoposide, and Cytarabine in Relapsed or Refractory Acute Myeloid Leukemia
NCT01127009
Docetaxel,Carboplatin,Trastuzumab and Bevacizumab for Breast Cancer and Bone Marrow Micrometastases
NCT00949247
Dacarbazine and Recombinant Interferon Alfa-2b in Treating Patients With Primary Uveal Melanoma With Genetic Imbalance
NCT01100528
Stereotactic Radiosurgery Using CyberKnife in Treating Women With Advanced or Recurrent Gynecological Malignancies
NCT01079832
Study of Tumor Samples in Patients Undergoing Radiation Therapy or Surgery For Primary Melanoma of the Eye
NCT00952939
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 30 |
| Phase 2 | 36 |
| Phase 3 | 30 |
| Phase 4 | 1 |
Therapeutic Areas
What the Pipeline for Case Comprehensive Cancer Center Shows
According to the ClinicalTrials.gov registry, Case Comprehensive Cancer Center is linked to 276 US clinical trials across every stage of research activity. Of those, 193 studies are currently recruiting — about 70% of the sponsor's indexed portfolio — and 65 are already marked complete, representing roughly 24% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
The phase mix for Case Comprehensive Cancer Center reports 31 late-stage studies (Phase 3 and Phase 4 combined) and 66 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
The top therapeutic focus area indexed for Case Comprehensive Cancer Center is Breast Cancer with 18 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology — how this data is sourced, computed, and verified.