Case Comprehensive Cancer Center

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Case Comprehensive Cancer Center sits in the top decile of US sponsors by registered trial count (#90 of 15,742 sponsors by registered trial count).

407 total trials 55 currently recruiting 257 completed early-phase tilt top decile by trial count

Case Comprehensive Cancer Center: 407 sponsored US clinical trials, 55 recruiting.

Case Comprehensive Cancer Center sponsors 407 registered US clinical trials on ClinicalTrials.gov, 55 of them currently recruiting, and 257 completed. 13 of these trials are in Phase 3-4 (later-stage) and 203 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Breast Cancer, with 18 trials.

Top-decile sponsor footprint

Case Comprehensive Cancer Center ranks in the top decile of sponsors by registered trial count (#90 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 37/100

257 of 325 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (79.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

407 total, page 1 of 9

RECRUITING Phase 2

Memory Avoidance Whole Brain Radiotherapy vs Hippocampal Avoidance Whole Brain Radiotherapy (Athena 2 Trial)

NCT07248228

RECRUITING NA

Feasibility and Acceptability of Wearable Sensors and ePROs in Early Phase Clinical Trials

NCT07541365

RECRUITING

Fatty Acid Binding Proteins and Markers of Cellular Senescence in Cancer Survivors

NCT07114614

RECRUITING Phase 1

Simulation-Free Celiac Plexus Pain Ablation Using Stereotactic Body Radiotherapy (SBRT) in Participants With Cancer-Related Celiac Pain

NCT07117032

RECRUITING NA

Scrambler Therapy for Chemotherapy-Induced Peripheral Neuropathy

NCT07219472

RECRUITING NA

Study to Investigate Efficacy of a Novel Probiotic on the Bacteriome and Mycobiome of Breast Cancer

NCT04362826

RECRUITING Phase 2

Pulmonary Rehabilitation in Advanced Lung Cancer Survivors

NCT07104630

RECRUITING Phase 1

Trial of Oligometastasis SBRT With Immediate, Simulation-Free Treatment Delivery (OLIGO-SWIFT)

NCT07079098

RECRUITING NA

Vitamin D Effects on Immune Microenvironment of Nonmelanoma Skin Cancer After Photodynamic Therapy (PDT)

NCT07241585

RECRUITING NA

Musculoskeletal Cancers Remote Monitoring and Care

NCT07129226

RECRUITING NA

Tongue Proactive Strengthening Exercise Program Following Partial/Hemi Glossectomy and Reconstruction

NCT07110142

RECRUITING Phase 2

Trifluridine/Tipiracil + Oxaliplatin in Participants With Advanced or Metastatic Biliary Tract Cancer

NCT07146646

RECRUITING NA

Pre-Op MRI on Margin Status for Transoral Robotic Surgery for HPV+ Tonsillar Squamous Cell Carcinoma

NCT07060261

RECRUITING NA

Artificial Intelligence-Powered Support For Quality Of Life Improvement In Participants With Cancer

NCT07167056

RECRUITING NA

Investigation of Impact of AI on Prostate Cancer Workflow

NCT07084779

RECRUITING Phase 1

Prehabilitation for EOC, Fallopian Tube, Primary Peritoneal Carcinoma and Pancreatic Cancer w/ NACT

NCT06412510

RECRUITING Phase 2

Co-Transplant of an Unmodified Haplo-Identical Graft With Cord Blood

NCT06904482

RECRUITING Phase 2

A Phase 2 and Pharmacodynamic Study of Sitagliptin in Patients With Progressive Grade 4 Gliomas

NCT07003542

RECRUITING NA

ECM and Monitoring w/ Alio Smart Patch in Cancer Pts Receiving Chemotherapy

NCT06657183

RECRUITING Phase 2

Cabazitaxel +/- Carboplatin vs 177Lu-PSMA-617 in Metastatic Castrate-resistant Prostate Cancer

NCT06738303

RECRUITING NA

Histotripsy Plus Chemotherapy vs Chemotherapy Alone for Advanced Colorectal Liver Metastasis

NCT07044362

RECRUITING Phase 2

Antibiotic Treatment Effects on Intratumoral Bacteria Modulation in Surgical Patients With Oral Cancer

NCT06627270

RECRUITING NA

Multi-Site Detection of Barrett's Esophagus in Patients Without Chronic GERD Symptoms

NCT06687603

RECRUITING Phase 2

Partial Cystectomy & Extended Pelvic Lymph Node Dissection With SOC Perioperative Systemic Therapy

NCT06290687

RECRUITING

Vulvovaginal Graft-versus-Host Disease: Diagnosis and Microbiome Evaluation

NCT06649201

RECRUITING NA

EQUITY GI: A Prospective Study to Enhance Quality, Inclusivity, and Trial Participation in Black Patients With Gastrointestinal Cancer.

NCT06263088

RECRUITING NA

Decreasing Chemotherapy Induced Distress Using Immersive Virtual Reality in Patients With Cancer

NCT06446115

RECRUITING NA

Development of MRF for Characterization of Brain Tumors After Radiotherapy

NCT06101069

RECRUITING NA

Brain MRF in Children, Adolescents and Young Adults With Acute Leukemia

NCT06421155

RECRUITING NA

Metabolic Impact of Prospective Controlled Mediterranean Type Diets on Prostate Cancer

NCT05590624

RECRUITING NA

Linking Somatic Mutation Rate With Baseline Exposure in East Palestine

NCT06357845

RECRUITING NA

Promoting Access, Resources and Treatment Through Novel and Equitable Solutions for Cancer Care

NCT06481774

RECRUITING NA

Fasting During Neoadjuvant Chemotherapy in Patient With Epithelial Ovarian Cancer

NCT06386887

RECRUITING Phase 2

MDRT in Prostate Cancer Treated With Long-term Androgen Deprivation Therapy in the STAMPEDE Trial (METANOVA)

NCT06150417

RECRUITING NA

Nephroureterectomy With and Without Lymph Node Dissection for Upper Tract Urothelial Cell Carcinoma

NCT06262516

RECRUITING NA

Glioblastoma Remote Monitoring and Care - Research Protocol

NCT06129760

RECRUITING Phase 1

Prospective Surgical Study on the Pattern of Electrical Activity in High Grade Glioma as a Predictor of Progression

NCT05565118

RECRUITING NA

Single-Port Transvesical Partial Prostatectomy Versus High Intensity Focused Ultrasound

NCT05610852

RECRUITING NA

Exercise Therapy and Radiation Therapy (EXERT) for Metastatic Prostate Cancer

NCT04556045

RECRUITING Phase 2

Repeat Breast Conserving Surgery Followed by Daily Partial Breast Irradiation in Ipsilateral Breast

NCT06129747

RECRUITING NA

Transplantation of Reconstructed Renal Allografts Following Ex-Vivo Partial Nephrectomy

NCT05725421

RECRUITING NA

Breast Margin Study: Routine Cavity Shave Margins Vs. Selective Margins Using Savi Scout®

NCT05825482

RECRUITING NA

Cleveland African American Prostate Cancer Project

NCT05469269

RECRUITING NA

Unintentional Weight Loss and Cancer: A Prospective Trial of Patient-centered Weight Tracking Combin

NCT05481697

RECRUITING NA

Patient Navigator PRE-ACT Educational Intervention to Promote Decision Making Among Minorities

NCT05701085

RECRUITING Phase 3

Is Intraperitoneal Drainage Necessary Following Distal Pancreatectomy?

NCT05720338

RECRUITING Phase 1

Disulfiram With Copper Gluconate and Liposomal Doxorubicin in Treatment-Refractory Sarcomas

NCT05210374

RECRUITING Phase 2

Methimazole in Patients With Progressive Glioblastoma

NCT05607407

RECRUITING

The Utility and Feasibility of Mt-sDNA as a Surveillance Procedure in Colorectal Cancer Survivors

NCT04624555

RECRUITING Phase 2

Alteration of the Immune Microenvironment in Basal Cell Carcinoma Following Photodynamic Therapy

NCT05020912

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Phase Distribution

PhaseTrial count
Phase 1 87
Phase 2 116
Phase 3 12
Phase 4 1

What is open in the Case Comprehensive Cancer Center pipeline

55 recruiting of 407 indexed (14% open); 257 completed (63%).

Phase mix: 13 late (III/IV) vs 203 early (I/II) (early-phase heavy).

Top condition: Breast Cancer (18 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Case Comprehensive Cancer Center: open-pipeline peers nationwide

Peers matched on 407 registered trials and 14% open enrollment, not the therapeutic-area sidebar.

Case Comprehensive Cancer Center sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 10%15%20%25% Total trials Recruiting share Case Comprehensive Cancer CenterUniversity of NebraskaTakedaUniversity of Kansas Medical CenterSt. Jude Children's Research HospitalBeth Israel Deaconess Medical CenterWayne State UniversityUniversity of MichiganAlbany Medical College
Case Comprehensive Cancer Center sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Case Comprehensive Cancer Center sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 407 trials (± recruiting share)

Sponsors near 14% open enrollment (± trial volume)

What to do with this Case Comprehensive Cancer Center page

407 registered trials is a research-attention snapshot, not an endorsement of Case Comprehensive Cancer Center or any single study.

  • 55 of Case Comprehensive Cancer Center's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Breast Cancer is the condition Case Comprehensive Cancer Center studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Breast Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Case Comprehensive Cancer Center pipeline card: 407 registered trials from official public datasets.Report a data error.