Case Comprehensive Cancer Center

276 total trials 193 currently recruiting 65 completed

Trial Pipeline

RECRUITING NA

Scrambler Therapy for Chemotherapy-Induced Peripheral Neuropathy

NCT07219472

RECRUITING Phase 2

Pulmonary Rehabilitation in Advanced Lung Cancer Survivors

NCT07104630

RECRUITING Phase 1

Trial of Oligometastasis SBRT With Immediate, Simulation-Free Treatment Delivery (OLIGO-SWIFT)

NCT07079098

RECRUITING NA

Musculoskeletal Cancers Remote Monitoring and Care

NCT07129226

RECRUITING NA

Tongue Proactive Strengthening Exercise Program Following Partial/Hemi Glossectomy and Reconstruction

NCT07110142

RECRUITING Phase 2

Trifluridine/Tipiracil + Oxaliplatin in Participants With Advanced or Metastatic Biliary Tract Cancer

NCT07146646

RECRUITING NA

Artificial Intelligence-Powered Support For Quality Of Life Improvement In Participants With Cancer

NCT07167056

RECRUITING NA

Investigation of Impact of AI on Prostate Cancer Workflow

NCT07084779

RECRUITING Phase 1

Prehabilitation for EOC, Fallopian Tube, Primary Peritoneal Carcinoma and Pancreatic Cancer w/ NACT

NCT06412510

RECRUITING Phase 2

Co-Transplant of an Unmodified Haplo-Identical Graft With Cord Blood

NCT06904482

RECRUITING Phase 2

A Phase 2 and Pharmacodynamic Study of Sitagliptin in Patients With Progressive Grade 4 Gliomas

NCT07003542

RECRUITING NA

ECM and Monitoring w/ Alio Smart Patch in Cancer Pts Receiving Chemotherapy

NCT06657183

RECRUITING Phase 2

Cabazitaxel +/- Carboplatin vs 177Lu-PSMA-617 in Metastatic Castrate-resistant Prostate Cancer

NCT06738303

RECRUITING NA

Histotripsy Plus Chemotherapy vs Chemotherapy Alone for Advanced Colorectal Liver Metastasis

NCT07044362

RECRUITING Phase 2

Antibiotic Treatment Effects on Intratumoral Bacteria Modulation in Surgical Patients With Oral Cancer

NCT06627270

RECRUITING NA

Multi-Site Detection of Barrett's Esophagus in Patients Without Chronic GERD Symptoms

NCT06687603

RECRUITING Phase 2

Partial Cystectomy & Extended Pelvic Lymph Node Dissection With SOC Perioperative Systemic Therapy

NCT06290687

RECRUITING

Vulvovaginal Graft-versus-Host Disease: Diagnosis and Microbiome Evaluation

NCT06649201

RECRUITING NA

EQUITY GI: A Prospective Study to Enhance Quality, Inclusivity, and Trial Participation in Black Patients With Gastrointestinal Cancer.

NCT06263088

RECRUITING NA

Decreasing Chemotherapy Induced Distress Using Immersive Virtual Reality in Patients With Cancer

NCT06446115

RECRUITING NA

Development of MRF for Characterization of Brain Tumors After Radiotherapy

NCT06101069

RECRUITING NA

Brain MRF in Children, Adolescents and Young Adults With Acute Leukemia

NCT06421155

RECRUITING NA

Metabolic Impact of Prospective Controlled Mediterranean Type Diets on Prostate Cancer

NCT05590624

RECRUITING NA

Linking Somatic Mutation Rate With Baseline Exposure in East Palestine

NCT06357845

RECRUITING NA

Promoting Access, Resources and Treatment Through Novel and Equitable Solutions for Cancer Care

NCT06481774

RECRUITING NA

Fasting During Neoadjuvant Chemotherapy in Patient With Epithelial Ovarian Cancer

NCT06386887

RECRUITING Phase 2

MDRT in Prostate Cancer Treated With Long-term Androgen Deprivation Therapy in the STAMPEDE Trial (METANOVA)

NCT06150417

RECRUITING NA

Nephroureterectomy With and Without Lymph Node Dissection for Upper Tract Urothelial Cell Carcinoma

NCT06262516

RECRUITING NA

Glioblastoma Remote Monitoring and Care - Research Protocol

NCT06129760

RECRUITING Phase 1

Prospective Surgical Study on the Pattern of Electrical Activity in High Grade Glioma as a Predictor of Progression

NCT05565118

RECRUITING NA

Single-Port Transvesical Partial Prostatectomy Versus High Intensity Focused Ultrasound

NCT05610852

RECRUITING NA

Exercise Therapy and Radiation Therapy (EXERT) for Metastatic Prostate Cancer

NCT04556045

RECRUITING Phase 2

Repeat Breast Conserving Surgery Followed by Daily Partial Breast Irradiation in Ipsilateral Breast

NCT06129747

RECRUITING NA

Transplantation of Reconstructed Renal Allografts Following Ex-Vivo Partial Nephrectomy

NCT05725421

RECRUITING NA

Breast Margin Study: Routine Cavity Shave Margins Vs. Selective Margins Using Savi Scout®

NCT05825482

RECRUITING NA

Cleveland African American Prostate Cancer Project

NCT05469269

RECRUITING NA

Unintentional Weight Loss and Cancer: A Prospective Trial of Patient-centered Weight Tracking Combin

NCT05481697

RECRUITING NA

Patient Navigator PRE-ACT Educational Intervention to Promote Decision Making Among Minorities

NCT05701085

RECRUITING Phase 3

Is Intraperitoneal Drainage Necessary Following Distal Pancreatectomy?

NCT05720338

RECRUITING Phase 1

Disulfiram With Copper Gluconate and Liposomal Doxorubicin in Treatment-Refractory Sarcomas

NCT05210374

RECRUITING Phase 2

Methimazole in Patients With Progressive Glioblastoma

NCT05607407

RECRUITING

The Utility and Feasibility of Mt-sDNA as a Surveillance Procedure in Colorectal Cancer Survivors

NCT04624555

RECRUITING Phase 2

Alteration of the Immune Microenvironment in Basal Cell Carcinoma Following Photodynamic Therapy

NCT05020912

RECRUITING

Genomic Analysis of Families With a History of Discordant Cancers

NCT04860453

RECRUITING Early Phase 1

Study of Nicotinamide Riboside Supplementation in Allogeneic Hematopoietic Cell Transplantation

NCT04332341

RECRUITING Phase 2

Single- vs. Two-Fraction Spine Stereotactic Radiosurgery for the Treatment of Vertebral Metastases

NCT04218617

RECRUITING

Proton Therapy Patient Registry

NCT02986048

RECRUITING Phase 1

Neoadjuvant Radiosurgery for Resectable Brain Metastases: Phase I/II Study

NCT01891318

ACTIVE NOT RECRUITING NA

Abbreviated MBCT for Depression in Older African American/Black Breast Cancer Survivors

NCT06336538

ACTIVE NOT RECRUITING NA

Developing Inclusive Support and Intervention for Spanish-speaking Latiné Prostate Cancer Survivors

NCT06435871

ACTIVE NOT RECRUITING NA

Individualized Treatments in Adults With Relapsed/Refractory Cancers

NCT06024603

ACTIVE NOT RECRUITING NA

Early Detection of Multiple Myeloma to Fight Cancer Disparities: A Screening and Patient Navigation Program

NCT05831358

ACTIVE NOT RECRUITING Phase 1

Ivosidenib + mFOLFIRINOX in Patients With Resectable Pancreatic Adenocarcinoma

NCT05209074

ACTIVE NOT RECRUITING NA

Interventional Program Educates, Identifies + Overcomes Barriers to Complete Screening Mammography

NCT04348123

ACTIVE NOT RECRUITING Phase 1

Low-Dose-Rate Brachytherapy Combined With Immune Checkpoint Inhibition in Cancer

NCT04620603

ACTIVE NOT RECRUITING Phase 2

CPX-351 as a Novel Approach for the Treatment of Older Patients With AML and MDS

NCT04668885

ACTIVE NOT RECRUITING NA

Improving Understanding of Brain Tumors Through Preservation of Biologically Active Brain Tissue

NCT04545177

ACTIVE NOT RECRUITING Phase 2

Targeted Therapy With CDK4/6 Inhibitors in Chemo-Refractory, Rb Wild-Type Extensive SCLC

NCT04010357

ACTIVE NOT RECRUITING Phase 1

Venetoclax in Combination With BEAM Conditioning Regimen for ASCT in Non-Hodgkin Lymphoma

NCT03713580

ACTIVE NOT RECRUITING Phase 1

Ibrutinib With Radiation and Temozolomide in Patients With Newly Diagnosed Glioblastoma

NCT03535350

ACTIVE NOT RECRUITING Phase 1

Ruxolitinib With Radiation and Temozolomide for Grade III Gliomas and Glioblastoma

NCT03514069

ACTIVE NOT RECRUITING NA

Evaluation of an Integrated Imaging System For In Vivo Detection of Fluorescently Labeled Lesions

NCT02802553

ACTIVE NOT RECRUITING Phase 1

Laser Interstitial Thermotherapy (LITT) Combined With Checkpoint Inhibitor for Recurrent GBM (RGBM)

NCT03277638

ACTIVE NOT RECRUITING

Transanal Total Mesorectal Excision for Rectal Cancer on Anal Physiology + Fecal Incontinence

NCT03283540

ACTIVE NOT RECRUITING NA

Multi-Parametric Quantitative MR Imaging in Evaluation of Brain Tumors

NCT02956291

ACTIVE NOT RECRUITING Phase 1

Stereotactic Radiosurgery in Treating Patients With Large Brain Metastases

NCT01843413

COMPLETED NA

Effects of Lavender Aromatherapy on Patient Anxiety During Mohs Micrographic Surgery

NCT06167096

COMPLETED NA

A Prospective Study to Evaluate Continuous Positive Airway Pressure Devices to Reduce Pulmonary Dose

NCT05142358

COMPLETED NA

Multidimensional Prehabilitation in Pancreatic Surgery for Pancreatic and Periampullary Neoplasms

NCT05225038

COMPLETED NA

Evaluating the Effectiveness of an Individualized Nutrition and Physical Activity Counseling Program

NCT04365569

COMPLETED Phase 1

Neoadjuvant-Adjuvant Pembrolizumab in Resectable Advanced Basal Cell Carcinoma of H&N

NCT04323202

COMPLETED NA

C-FLASH (Cigarillo Flavor and Abuse Liability, Attention, and Substitution in youtH)

NCT04358705

COMPLETED

Leveraging ctDNA Analysis to Improve Early Detection of Cancer Recurrence in the High-Risk Melanoma Setting

NCT05079113

COMPLETED Phase 2

Regorafenib in Bevacizumab Refractory Recurrent Glioblastoma

NCT04051606

COMPLETED NA

Feasibility of a Culturally-Specific Video Text Cessation Intervention With AA Quitline Callers

NCT03927976

COMPLETED NA

Role of Magnetic Resonance Fingerprinting and Quantitative MR Imaging in Breast Cancer

NCT03650803

COMPLETED Phase 1

Osimertinib With Stereotactic Radiosurgery (SRS) in Brain Metastases From EGFR Positive NSCLC

NCT03535363

COMPLETED NA

Improved Intra-operative Safety From Optimal Selection of Anti-slip Surface

NCT03573557

COMPLETED Phase 2

Thiotepa Plus Fludarabine+ Melphalan as the Preparative Regime for Alternative Donor Transplantation

NCT03342196

COMPLETED

A Pilot Study of [Ga-68]PSMA PET/MRI for the Assessment of PSMA-positive Tumors

NCT02978586

COMPLETED NA

Music Therapy and Hematopoietic Stem Cell Transplant

NCT03378089

COMPLETED Early Phase 1

End Nicotine Dependence Clinic

NCT03290430

COMPLETED Phase 2

Pembrolizumab Alone or Sequentially Following Single Fraction Non-ablative Radiation to One of the Target Lesions, in Previously Treated Patients With Stage IV NSCLC

NCT02658097

COMPLETED NA

Optimal Timing of Postoperative Magnetic Resonance Imaging (MRI) in Patients With Extradural Spinal

NCT02790294

COMPLETED Phase 2

Axitinib Given on an Individualized Schedule for Metastatic Renal Cell Cancer

NCT02579811

COMPLETED Phase 2

Treatment of Brain Metastases From Breast Cancer With Eribulin Mesylate

NCT02581839

COMPLETED Phase 1

Hematopoietic Stem Cell Transplant for Sickle Cell Disease

NCT02065596

COMPLETED Phase 1

Targeted Marrow Irradiation, Fludarabine Phosphate, and Busulfan Before Donor Progenitor Cell Transplant in Treating Patients With Hematologic Malignancies

NCT02129582

COMPLETED Early Phase 1

Dose Monitoring of Busulfan and Combination Chemotherapy in Hodgkin or Non-Hodgkin Lymphoma Undergoing Stem Cell Transplant

NCT01959477

COMPLETED NA

Tailoring Patient Education to Perceived Risk for Falls in Hospitalized Oncology Patients

NCT02081794

COMPLETED Phase 2

Enzalutamide in Patients With High-risk Prostate Cancer

NCT01927627

COMPLETED NA

Feasibility of a Team Approach for Discussing Prognosis and Treatment Goals in Breast Cancer

NCT01876238

COMPLETED Phase 1

Carboplatin, Gemcitabine Hydrochloride, and Stereotactic Body Radiation Therapy in Gynecological Cancer

NCT01652794

COMPLETED NA

Assisted Exercise in Obese Endometrial Cancer Patients

NCT01870947

COMPLETED Phase 1

Methoxyamine and Fludarabine Phosphate in Treating Patients With Relapsed or Refractory Hematologic Malignancies

NCT01658319

COMPLETED Phase 1

Bortezomib, Mitoxantrone, Etoposide, and Cytarabine in Relapsed or Refractory Acute Myeloid Leukemia

NCT01127009

COMPLETED Early Phase 1

Docetaxel,Carboplatin,Trastuzumab and Bevacizumab for Breast Cancer and Bone Marrow Micrometastases

NCT00949247

COMPLETED Phase 2

Dacarbazine and Recombinant Interferon Alfa-2b in Treating Patients With Primary Uveal Melanoma With Genetic Imbalance

NCT01100528

COMPLETED Phase 2

Stereotactic Radiosurgery Using CyberKnife in Treating Women With Advanced or Recurrent Gynecological Malignancies

NCT01079832

COMPLETED

Study of Tumor Samples in Patients Undergoing Radiation Therapy or Surgery For Primary Melanoma of the Eye

NCT00952939

Phase Distribution

PhaseTrial count
Phase 1 30
Phase 2 36
Phase 3 30
Phase 4 1

What the Pipeline for Case Comprehensive Cancer Center Shows

According to the ClinicalTrials.gov registry, Case Comprehensive Cancer Center is linked to 276 US clinical trials across every stage of research activity. Of those, 193 studies are currently recruiting — about 70% of the sponsor's indexed portfolio — and 65 are already marked complete, representing roughly 24% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

The phase mix for Case Comprehensive Cancer Center reports 31 late-stage studies (Phase 3 and Phase 4 combined) and 66 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

The top therapeutic focus area indexed for Case Comprehensive Cancer Center is Breast Cancer with 18 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial