Vanda Pharmaceuticals

68 total trials 15 currently recruiting 45 completed

Vanda Pharmaceuticals sponsors 68 registered US clinical trials on ClinicalTrials.gov, 15 of them currently recruiting, and 45 completed. 27 of these trials are in Phase 3-4 (later-stage) and 37 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Schizophrenia, with 5 trials.

Trial Pipeline

68 total, page 1 of 2

RECRUITING Phase 3

A Study to Evaluate Tradipitant on Treating Nausea and Vomiting Induced by GLP-1R Agonist Use

NCT07446439

RECRUITING Phase 3

Open Label Study to Investigate the Safety and Efficacy of Ponesimod in Moderate-to-Severe Chronic Plaque Psoriasis

NCT07362017

RECRUITING Phase 2

An Eight-Week Study to Evaluate the Safety and Efficacy of VSJ-110 Compared to Placebo in the Treatment of Dry Eye

NCT07179055

RECRUITING Phase 3

Study to Evaluate the Efficacy and Safety of VQW-765 for the On-Demand Treatment of Social Anxiety Disorder

NCT07221578

RECRUITING Phase 2

Evaluation of Efficacy and Safety of Iloperidone for the Treatment of Participants With Uncontrolled Hypertension

NCT07090161

RECRUITING Phase 3

Randomized Withdrawal Study in Patients With Schizophrenia

NCT06961968

RECRUITING Phase 3

Evaluating the Effects of Tasimelteon vs. Placebo in Treating Pediatric Insomnia

NCT06953869

RECRUITING Phase 3

Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder

NCT06830044

RECRUITING Phase 2

A Study to Evaluate the Safety and Efficacy of VSJ-110 Compared to Placebo in the Treatment of Dry Eye

NCT06296966

RECRUITING Phase 4

Safety and Tolerability of Open-Labeled Iloperidone in Adolescents

NCT05648591

RECRUITING Phase 3

Evaluating the Effects of Tasimelteon in Individuals With Autism Spectrum Disorder (ASD) and Sleep Disturbances

NCT05361707

RECRUITING Phase 3

Evaluating the Effects of Tasimelteon vs. Placebo in Delayed Sleep-Wake Phase Disorder (DSWPD)

NCT04652882

RECRUITING Phase 1

Tolerability Study of Trichostatin A In Subjects With Relapsed or Refractory Hematologic Malignancies

NCT03838926

RECRUITING

Development of Clinical Database of Individuals With Smith-Magenis Syndrome and Sleep Disturbances

NCT03154697

RECRUITING

Patient Registry of Blind Subjects With Sleep-related Problems

NCT01195558

ACTIVE NOT RECRUITING Phase 1

Treatment of Charcot-Marie-Tooth Disease, Axonal, Type 2S (CMT2S) in an Individual Patient

NCT07223632

ACTIVE NOT RECRUITING Phase 2

Safety, Tolerability and Efficacy of Trichostatin A in Patients With Mild to Severe Onychomycosis

NCT07065773

ACTIVE NOT RECRUITING Phase 3

Motion Delos: An Open Label Safety and Efficacy of Tradipitant in Participants Affected by Motion Sickness

NCT06138613

NOT YET RECRUITING Phase 3

Study to Evaluate the Efficacy and Safety of Ponesimod (VSP-128) in Patients With Moderately to Severely Active Ulcerative Colitis

NCT07686081

COMPLETED Phase 2

A Study to Measure the Effects of Using Tradipitant on Nausea and Vomiting After GLP-1R Agonist Use

NCT06804603

COMPLETED Phase 1

Pharmacokinetic Study of VHX-896 and Iloperidone Tablets Under Steady-State Conditions

NCT06494397

COMPLETED Phase 3

Motion Serifos: A Study to Investigate the Efficacy of Tradipitant in Participants Affected by Motion Sickness

NCT05903924

COMPLETED Phase 1

Food Effect Study of VHX-896 in Healthy Volunteers

NCT06803290

COMPLETED Phase 1

Bioequivalence Study Between Tasimelteon Capsule Formulation and Liquid Suspension Formulation in Healthy Volunteers

NCT05572281

TERMINATED Phase 3

Study to Evaluate the Long-Term Safety and Efficacy of Imsidolimab (ANB019) in the Treatment of Subjects With GPP

NCT05366855

COMPLETED Phase 3

Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in the Treatment of Subjects With GPP

NCT05352893

COMPLETED Phase 3

Motion Syros: A Study to Investigate the Efficacy of Tradipitant in Subjects Affected by Motion Sickness

NCT04327661

COMPLETED Phase 2

A Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in the Treatment of Participants With Hidradenitis Suppurativa

NCT04856930

COMPLETED Phase 1

Bioequivalence Study Between VHX-896 Tablets and Iloperidone Tablets in Healthy Volunteers

NCT04969211

COMPLETED Phase 2

A Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in the Treatment of Participants With Acne Vulgaris

NCT04856917

TERMINATED Phase 2

A Study to Evaluate of the Efficacy and Safety of Imsidolimab (ANB019) in the Treatment of Acneiform Rash

NCT04697069

COMPLETED Phase 3

Evaluation of Efficacy and Safety of Iloperidone in the Acute Treatment of Manic or Mixed Episodes Associated With Bipolar I Disorder

NCT04819776

COMPLETED Phase 2

Evaluating the Effects of VQW-765 vs. Placebo in Performance Anxiety

NCT04800237

COMPLETED Phase 1

Effects of Tradipitant on Satiation, Gastric Volume, Gastric Accommodation, and Gastric Emptying in Healthy Volunteers

NCT04849559

TERMINATED Phase 2

A Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in the Treatment of Participants With Ichthyosis

NCT04697056

COMPLETED Phase 1

A Study to Evaluate Iloperidone Long-acting Injection (LAI) for the Treatment of Schizophrenia

NCT04712734

COMPLETED Phase 2

Safety and Efficacy of VSJ-110 in the Treatment of Allergic Conjunctivitis in Adults With a History of Ocular Allergies

NCT04622345

COMPLETED

WGS Analysis of COVID-19 Positive Patients

NCT04353401

TERMINATED Phase 3

Evaluating the Effects of Tradipitant vs. Placebo in Atopic Dermatitis (EPIONE2)

NCT04140695

COMPLETED Phase 1

Evaluating a New Iloperidone Titration Scheme in Bipolar I Disorder or Schizophrenia

NCT04127058

COMPLETED Phase 3

Evaluating the Safety and Efficacy of Tradipitant vs. Placebo in Idiopathic and Diabetic Gastroparesis

NCT04028492

COMPLETED Phase 2

A Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in Adults With Palmoplantar Pustulosis

NCT03633396

COMPLETED Phase 2

A Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in Adults With Generalized Pustular Psoriasis

NCT03619902

COMPLETED Phase 2

Motion Sifnos: A Study to Investigate the Efficacy of Tradipitant in Subjects Affected by Motion Sickness

NCT03772340

COMPLETED Phase 3

Evaluating the Effects of Tradipitant vs. Placebo in Atopic Dermatitis (EPIONE)

NCT03568331

COMPLETED Phase 3

Evaluating the Effects of Tasimelteon vs. Placebo on Jet Lag Type Insomnia

NCT03373201

COMPLETED Phase 2

Study to Assess the Efficacy of VLY-686 in Relieving Symptoms of Gastroparesis

NCT02970968

COMPLETED Phase 1

Study of the Pharmacokinetics and Safety of Tasimelteon in Children and Adolescents

NCT02776215

COMPLETED Phase 2

A Proof of Concept Study to Evaluate the Effects of Tasimelteon and Placebo in Travelers With Jet Lag Disorder

NCT03291041

COMPLETED Phase 2

Tradipitant in Treatment-resistant Pruritus Associated With Atopic Dermatitis

NCT02651714

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What the Pipeline for Vanda Pharmaceuticals Shows

According to the ClinicalTrials.gov registry, Vanda Pharmaceuticals is linked to 68 US clinical trials across every stage of research activity. Of those, 15 studies are currently recruiting, about 22% of the sponsor's indexed portfolio, and 45 are already marked complete, representing roughly 66% of the total.

The phase mix for Vanda Pharmaceuticals reports 27 late-stage studies (Phase 3 and Phase 4 combined) and 37 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Vanda Pharmaceuticals is Schizophrenia with 5 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.