Vanda Pharmaceuticals

Open enrollment across a mixed-phase pipeline

According to ClinicalTrials.gov-derived indexes, Vanda Pharmaceuticals sits in the top decile of US sponsors by registered trial count (#311 of 15,742 sponsors by registered trial count).

68 total trials 15 currently recruiting 45 completed top decile by trial count

Vanda Pharmaceuticals: 68 sponsored US clinical trials, 15 recruiting.

Vanda Pharmaceuticals sponsors 68 registered US clinical trials on ClinicalTrials.gov, 15 of them currently recruiting, and 45 completed. 27 of these trials are in Phase 3-4 (later-stage) and 37 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Schizophrenia, with 5 trials.

Top-decile sponsor footprint

Vanda Pharmaceuticals ranks in the top decile of sponsors by registered trial count (#311 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 69/100

45 of 49 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (91.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

68 total, page 1 of 2

RECRUITING Phase 3

A Study to Evaluate Tradipitant on Treating Nausea and Vomiting Induced by GLP-1R Agonist Use

NCT07446439

RECRUITING Phase 3

Open Label Study to Investigate the Safety and Efficacy of Ponesimod in Moderate-to-Severe Chronic Plaque Psoriasis

NCT07362017

RECRUITING Phase 2

An Eight-Week Study to Evaluate the Safety and Efficacy of VSJ-110 Compared to Placebo in the Treatment of Dry Eye

NCT07179055

RECRUITING Phase 3

Study to Evaluate the Efficacy and Safety of VQW-765 for the On-Demand Treatment of Social Anxiety Disorder

NCT07221578

RECRUITING Phase 2

Evaluation of Efficacy and Safety of Iloperidone for the Treatment of Participants With Uncontrolled Hypertension

NCT07090161

RECRUITING Phase 3

Randomized Withdrawal Study in Patients With Schizophrenia

NCT06961968

RECRUITING Phase 3

Evaluating the Effects of Tasimelteon vs. Placebo in Treating Pediatric Insomnia

NCT06953869

RECRUITING Phase 3

Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder

NCT06830044

RECRUITING Phase 2

A Study to Evaluate the Safety and Efficacy of VSJ-110 Compared to Placebo in the Treatment of Dry Eye

NCT06296966

RECRUITING Phase 4

Safety and Tolerability of Open-Labeled Iloperidone in Adolescents

NCT05648591

RECRUITING Phase 3

Evaluating the Effects of Tasimelteon in Individuals With Autism Spectrum Disorder (ASD) and Sleep Disturbances

NCT05361707

RECRUITING Phase 3

Evaluating the Effects of Tasimelteon vs. Placebo in Delayed Sleep-Wake Phase Disorder (DSWPD)

NCT04652882

RECRUITING Phase 1

Tolerability Study of Trichostatin A In Subjects With Relapsed or Refractory Hematologic Malignancies

NCT03838926

RECRUITING

Development of Clinical Database of Individuals With Smith-Magenis Syndrome and Sleep Disturbances

NCT03154697

RECRUITING

Patient Registry of Blind Subjects With Sleep-related Problems

NCT01195558

ACTIVE NOT RECRUITING Phase 1

Treatment of Charcot-Marie-Tooth Disease, Axonal, Type 2S (CMT2S) in an Individual Patient

NCT07223632

ACTIVE NOT RECRUITING Phase 2

Safety, Tolerability and Efficacy of Trichostatin A in Patients With Mild to Severe Onychomycosis

NCT07065773

ACTIVE NOT RECRUITING Phase 3

Motion Delos: An Open Label Safety and Efficacy of Tradipitant in Participants Affected by Motion Sickness

NCT06138613

NOT YET RECRUITING Phase 3

Study to Evaluate the Efficacy and Safety of Ponesimod (VSP-128) in Patients With Moderately to Severely Active Ulcerative Colitis

NCT07686081

COMPLETED Phase 2

A Study to Measure the Effects of Using Tradipitant on Nausea and Vomiting After GLP-1R Agonist Use

NCT06804603

COMPLETED Phase 1

Pharmacokinetic Study of VHX-896 and Iloperidone Tablets Under Steady-State Conditions

NCT06494397

COMPLETED Phase 3

Motion Serifos: A Study to Investigate the Efficacy of Tradipitant in Participants Affected by Motion Sickness

NCT05903924

COMPLETED Phase 1

Food Effect Study of VHX-896 in Healthy Volunteers

NCT06803290

COMPLETED Phase 1

Bioequivalence Study Between Tasimelteon Capsule Formulation and Liquid Suspension Formulation in Healthy Volunteers

NCT05572281

TERMINATED Phase 3

Study to Evaluate the Long-Term Safety and Efficacy of Imsidolimab (ANB019) in the Treatment of Subjects With GPP

NCT05366855

COMPLETED Phase 3

Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in the Treatment of Subjects With GPP

NCT05352893

COMPLETED Phase 3

Motion Syros: A Study to Investigate the Efficacy of Tradipitant in Subjects Affected by Motion Sickness

NCT04327661

COMPLETED Phase 2

A Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in the Treatment of Participants With Hidradenitis Suppurativa

NCT04856930

COMPLETED Phase 1

Bioequivalence Study Between VHX-896 Tablets and Iloperidone Tablets in Healthy Volunteers

NCT04969211

COMPLETED Phase 2

A Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in the Treatment of Participants With Acne Vulgaris

NCT04856917

TERMINATED Phase 2

A Study to Evaluate of the Efficacy and Safety of Imsidolimab (ANB019) in the Treatment of Acneiform Rash

NCT04697069

COMPLETED Phase 3

Evaluation of Efficacy and Safety of Iloperidone in the Acute Treatment of Manic or Mixed Episodes Associated With Bipolar I Disorder

NCT04819776

COMPLETED Phase 2

Evaluating the Effects of VQW-765 vs. Placebo in Performance Anxiety

NCT04800237

COMPLETED Phase 1

Effects of Tradipitant on Satiation, Gastric Volume, Gastric Accommodation, and Gastric Emptying in Healthy Volunteers

NCT04849559

TERMINATED Phase 2

A Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in the Treatment of Participants With Ichthyosis

NCT04697056

COMPLETED Phase 1

A Study to Evaluate Iloperidone Long-acting Injection (LAI) for the Treatment of Schizophrenia

NCT04712734

COMPLETED Phase 2

Safety and Efficacy of VSJ-110 in the Treatment of Allergic Conjunctivitis in Adults With a History of Ocular Allergies

NCT04622345

COMPLETED

WGS Analysis of COVID-19 Positive Patients

NCT04353401

TERMINATED Phase 3

Evaluating the Effects of Tradipitant vs. Placebo in Atopic Dermatitis (EPIONE2)

NCT04140695

COMPLETED Phase 1

Evaluating a New Iloperidone Titration Scheme in Bipolar I Disorder or Schizophrenia

NCT04127058

COMPLETED Phase 3

Evaluating the Safety and Efficacy of Tradipitant vs. Placebo in Idiopathic and Diabetic Gastroparesis

NCT04028492

COMPLETED Phase 2

A Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in Adults With Palmoplantar Pustulosis

NCT03633396

COMPLETED Phase 2

A Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in Adults With Generalized Pustular Psoriasis

NCT03619902

COMPLETED Phase 2

Motion Sifnos: A Study to Investigate the Efficacy of Tradipitant in Subjects Affected by Motion Sickness

NCT03772340

COMPLETED Phase 3

Evaluating the Effects of Tradipitant vs. Placebo in Atopic Dermatitis (EPIONE)

NCT03568331

COMPLETED Phase 3

Evaluating the Effects of Tasimelteon vs. Placebo on Jet Lag Type Insomnia

NCT03373201

COMPLETED Phase 2

Study to Assess the Efficacy of VLY-686 in Relieving Symptoms of Gastroparesis

NCT02970968

COMPLETED Phase 1

Study of the Pharmacokinetics and Safety of Tasimelteon in Children and Adolescents

NCT02776215

COMPLETED Phase 2

A Proof of Concept Study to Evaluate the Effects of Tasimelteon and Placebo in Travelers With Jet Lag Disorder

NCT03291041

COMPLETED Phase 2

Tradipitant in Treatment-resistant Pruritus Associated With Atopic Dermatitis

NCT02651714

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What is open in the Vanda Pharmaceuticals pipeline

15 recruiting of 68 indexed (22% open); 45 completed (66%).

Phase mix: 27 late (III/IV) vs 37 early (I/II) (balanced across stages).

Top condition: Schizophrenia (5 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Vanda Pharmaceuticals: open-pipeline peers nationwide

Peers matched on 68 registered trials and 22% open enrollment, not the therapeutic-area sidebar.

Vanda Pharmaceuticals sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0100200300400500 0%5%10%15%20%25% Total trials Recruiting share Vanda PharmaceuticalsMallinckrodtProvidence Health & ServicesTexas Tech UniversityUniversity of Colorado, BoulderBoston University Charles River CampusSt. Jude Children's Research HospitalALX OncologyBiosense Webster
Vanda Pharmaceuticals sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Vanda Pharmaceuticals sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 68 trials (± recruiting share)

Sponsors near 22% open enrollment (± trial volume)

What to do with this Vanda Pharmaceuticals page

68 registered trials is a research-attention snapshot, not an endorsement of Vanda Pharmaceuticals or any single study.

  • 15 of Vanda Pharmaceuticals's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Schizophrenia is the condition Vanda Pharmaceuticals studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Schizophrenia trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Vanda Pharmaceuticals pipeline card: 68 registered trials from official public datasets.Report a data error.