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NCT00004068 · ClinicalTrials.gov registry record · Phase 2

Irinotecan Followed by Radiation Therapy and Temozolomide in Treating Children With Newly Diagnosed Brain Tumor

A Phase 2 study, sponsored by St. Jude Children's Research Hospital.

Completed
Registry status
Phase 2
Development phase
53
Enrollment target

NCT00004068 is a Phase 2 study that has completed, run by St. Jude Children's Research Hospital. The registered enrollment target is 53 participants.

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The verdict

NCT00004068, a Phase 2 study, has completed, sponsored by St. Jude Children's Research Hospital.

COMPLETED
Registry status
Phase 2
Development phase
53 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining chemotherapy with radiation therapy may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of irinotecan followed by radiation therapy and temozolomide in treating children who have newly diagnosed brain tumor.

Interventions

  • DRUG temozolomide
  • PROCEDURE conventional surgery
  • RADIATION radiation therapy
  • DRUG irinotecan hydrochloride

Trial Details

FieldValue
Enrollment Target 53 participants
Start Date 1999-03
Est. Completion 2003-04
Phase Phase 2

What the Registry Record Tells You About NCT00004068

The ClinicalTrials.gov registry entry for NCT00004068 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 53 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is St. Jude Children's Research Hospital, which has 410 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which temozolomide is the first listed.

NCT00004068 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00004068 about?

NCT00004068 is a clinical study titled "Irinotecan Followed by Radiation Therapy and Temozolomide in Treating Children With Newly Diagnosed Brain Tumor". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining chemotherapy with radiation therapy may kill more tumor cells. PURPOSE: Phase II trial to study the effe...

What is the current status of trial NCT00004068?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 53 participants. The study started on 1999-03. Estimated completion is 2003-04.

What interventions are being tested in trial NCT00004068?

The interventions under investigation include: temozolomide (DRUG), conventional surgery (PROCEDURE), radiation therapy (RADIATION), irinotecan hydrochloride (DRUG).

Who is sponsoring clinical trial NCT00004068?

This trial is sponsored by St. Jude Children's Research Hospital, which has 410 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.