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NCT00187031 · ClinicalTrials.gov registry record · Phase 2
A Phase II Study of Topotecan in Children With Recurrent Wilms Tumor
A Phase 2 study, sponsored by St. Jude Children's Research Hospital.
- Completed
- Registry status
- Phase 2
- Development phase
- 37
- Enrollment target
NCT00187031: Completed Phase 2 study, sponsored by St. Jude Children's Research Hospital.
NCT00187031 is a Phase 2 study that has completed, run by St. Jude Children's Research Hospital. The registered enrollment target is 37 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (72% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00187031, a Phase 2 study, has completed, sponsored by St. Jude Children's Research Hospital.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 37 participants
- Enrollment target
Study Summary
In spite of the overall success of treating Wilms tumor, certain patients still have poor clinical outcomes. The sub-optimal outcomes for patients with anaplastic histology and recurrent Wilms tumor warrant the identification of new therapeutic agents. The objective of this trial is to estimate the response rate to two cycles of intravenous topotecan in children with recurrent Wilms tumor of favorable histology that is refractory to standard curative therapy.
Interventions
- DRUG Topotecan, Filgrastim (G-CSF), Pegfilgrastim
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 37 participants |
| Start Date | 2002-11 |
| Est. Completion | 2007-10 |
| Phase | Phase 2 |
What the finished NCT00187031 record still lists
NCT00187031 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 37 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (72% lower).
The record links to 0 conditions, and to 1 intervention - of which Topotecan, Filgrastim (G-CSF), Pegfilgrastim is the first listed.
NCT00187031 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00187031 about?
NCT00187031 is a clinical study titled "A Phase II Study of Topotecan in Children With Recurrent Wilms Tumor". In spite of the overall success of treating Wilms tumor, certain patients still have poor clinical outcomes. The sub-optimal outcomes for patients with anaplastic histology and recurrent Wilms tumor warrant the identification of new therapeutic agents. The objective of this trial is to estimate the ...
What is the current status of trial NCT00187031?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 37 participants. The study started on 2002-11. Estimated completion is 2007-10.
What interventions are being tested in trial NCT00187031?
The interventions under investigation include: Topotecan, Filgrastim (G-CSF), Pegfilgrastim (DRUG).
Who is sponsoring clinical trial NCT00187031?
This trial is sponsored by St. Jude Children's Research Hospital, which has 410 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00187031's enrollment target sits among peer trials
37 1484th of 2000 higher than 505 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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