St. Jude Children's Research Hospital

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, St. Jude Children's Research Hospital sits in the top decile of US sponsors by registered trial count (#87 of 15,742 sponsors by registered trial count).

410 total trials 90 currently recruiting 227 completed early-phase tilt top decile by trial count

St. Jude Children's Research Hospital: 410 sponsored US clinical trials, 90 recruiting.

St. Jude Children's Research Hospital sponsors 410 registered US clinical trials on ClinicalTrials.gov, 90 of them currently recruiting, and 227 completed. 19 of these trials are in Phase 3-4 (later-stage) and 173 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Sickle Cell Disease, with 17 trials.

Top-decile sponsor footprint

St. Jude Children's Research Hospital ranks in the top decile of sponsors by registered trial count (#87 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 59/100

227 of 259 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (87.6%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

410 total, page 7 of 9

COMPLETED

Immunogenicity and Safety of Inactivated H1N1 Swine-origin Influenza Monovalent Vaccine in Immunocompromised Children and Young Adults

NCT01000571

COMPLETED Phase 1

Clinical Trial Evaluating the Combination of Vandetanib and Dasatinib During and After Radiation Therapy (RT) in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG)

NCT00996723

COMPLETED

Surveillance of Influenza Virus Shedding and Immunologic Response in Immunocompromised Children and Young Adults

NCT00998803

TERMINATED NA

The Effects of Ankle Foot Orthoses on Gait Efficiency in Children With Acute Lymphoblastic Leukemia and Foot Drop

NCT01001390

COMPLETED Phase 1

Sorafenib in Combination With Cytarabine and Clofarabine in Patients With Refractory or Relapsed Hematologic Malignancies

NCT00908167

COMPLETED

Avian Influenza Studies In Lebanon

NCT01107262

COMPLETED

Diagnosis and Characterization of Dengue Fever in Children

NCT00946218

COMPLETED

Motor Proficiency And Physical Activity in Adult Survivors of Childhood Acute Lymphoblastic Leukemia (ALL)

NCT01047020

COMPLETED

Long Term Effects of Erythrocyte Lysis

NCT00842621

COMPLETED Phase 1

Haploidentical Hematopoietic Stem Cell Transplantation Using A Novel Clofarabine Containing Conditioning Regimen For Patients With Refractory Hematologic Malignancies

NCT00824135

TERMINATED Phase 2

Neuroblastoma Protocol 2008: Therapy for Children With Advanced Stage High Risk Neuroblastoma

NCT00808899

COMPLETED Phase 1

A Phase I Trial Of The Humanized Anti-GD2 Antibody In Children And Adolescents With Neuroblastoma, Osteosarcoma, Ewing Sarcoma and Melanoma

NCT00743496

COMPLETED Phase 1

A Study of a Live Intranasal Influenza Vaccine in Children With Cancer

NCT00906750

COMPLETED NA

Efficacy of Tobacco Quitline for Cancer Survivors

NCT00827866

COMPLETED

Pilot Study Of Primary And Secondary Attention-Deficit/Hyperactivity Disorder Among Survivors Of Childhood Cancer

NCT01032811

COMPLETED Phase 1

Pilot Study of Expanded, Donor Natural Killer Cell Infusions for Refractory Non-B Lineage Hematologic Malignancies and Solid Tumors

NCT00640796

COMPLETED Phase 3

Clofarabine Plus Cytarabine Versus Conventional Induction Therapy And A Study Of NK Cell Transplantation In Newly Diagnosed Acute Myeloid Leukemia

NCT00703820

COMPLETED Phase 1

A Trial of Everolimus and Bevacizumab in Children With Recurrent Solid Tumors

NCT00756340

COMPLETED Phase 2

A Study of Bevacizumab in Combination With Chemotherapy for Treatment of Osteosarcoma

NCT00667342

COMPLETED

Bone Marrow for Hemoglobinopathy Research

NCT00669305

COMPLETED NA

A Pilot Study to Examine Sleep and Fatigue in Pediatric Brain Tumor Patients Hospitalized for High Dose Chemotherapy

NCT00666614

COMPLETED

Planning Margin Requirements for Pediatric Radiation Oncology

NCT00704613

COMPLETED

A Pilot Study of PET-CT in the Assessment of Pulmonary Nodules in Children With Malignant Solid Tumors

NCT00629460

COMPLETED NA

Aerobic and Strengthening Exercise for Acute Leukemia

NCT00766311

COMPLETED Phase 2

Mismatched Family Member Donor Transplantation for Children and Young Adults With High Risk Hematological Malignancies

NCT00566696

COMPLETED

Prospective Surveillance For Respiratory Virus Infections In Children Undergoing Hematopoietic Stem Cell Transplantation

NCT00667303

COMPLETED Phase 1

Phase I Study of Bevacizumab and Sorafenib Combined With Low Dose Cyclophosphamide in Patients With Refractory Solid Tumors and Leukemia

NCT00665990

COMPLETED Phase 3

Total Therapy Study XVI for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia

NCT00549848

COMPLETED Phase 1

Dose Escalation Study Of Palifermin in Pediatric Research Participants Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

NCT00701688

TERMINATED Phase 1

Evaluate Tolerability of a Multi-envelope, Prime-boost HIV Vaccine in Healthy Adults

NCT00623753

COMPLETED

Working Memory Performance Among Childhood Brain Tumor Survivors

NCT00693914

COMPLETED Phase 1

Vandetanib and Radiation Therapy in Treating Young Patients With Newly Diagnosed Diffuse Brainstem Glioma

NCT00472017

COMPLETED Phase 1

Pilot Study of Haploidentical Natural Killer Cell Infusions for Poor Prognosis Non-AML Hematologic Malignancies

NCT00697671

COMPLETED

Long Term Follow Up Of Patients Who Have Received Gene Therapy Or Gene Marked Products

NCT00695279

TERMINATED Phase 2

Hydroxyurea and Magnesium Pidolate to Treat People With Hemoglobin Sickle Cell Disease

NCT00532883

COMPLETED

Peripheral Blood Stem Cells Obtained From Normal Volunteers for Studying Retroviral Vector Mediated Gene Transfer Into Primitive Hematopoietic Cells and Vector Mediated Transgene Expression in Mature Hematopoietic Lineages

NCT00758992

TERMINATED Phase 3

Stroke With Transfusions Changing to Hydroxyurea

NCT00122980

COMPLETED Phase 2

Chemotherapy With Low-Dose Radiation for Pediatric Hodgkin Lymphoma

NCT00352027

COMPLETED

DNA Analysis of Tumor Tissue Samples From Patients With Diffuse Brain Stem Glioma

NCT00899834

COMPLETED Phase 1

Compassionate Use of Erwinase For Pediatric Patients With Acute Lymphoblastic Leukemia Or Non Hodgkins Lymphoma

NCT00693602

COMPLETED

Long Term Effects of Hydroxyurea Therapy in Children With Sickle Cell Disease

NCT00305175

COMPLETED NA

Partially Matched Stem Cell Transplantation for Patients With Refractory Severe Aplastic Anemia or Refractory Cytopenias

NCT00244010

COMPLETED

Pilot Study of Non-Invasive Assessment of Hepatic And Myocardial Iron Through T2* Magnet Resonance Imaging (MRI) In Patients With Iron Overload

NCT00675038

COMPLETED NA

Natural Killer (NK) Cell Transplantation for AML

NCT00187096

COMPLETED Phase 1

ZD1839 and Oral Irinotecan in Treating Young Patients With Refractory Solid Tumors

NCT00132158

COMPLETED Phase 2

Therapy for Children With Neuroblastoma

NCT00135135

COMPLETED

Neurologic Morbidity and Disability in Acute Lymphoblastic Leukemia Survivors

NCT00664131

COMPLETED Phase 2

Stem Cell Transplantation as Immunotherapy for Hematologic Malignancies

NCT00143559

COMPLETED Phase 1

Haploidentical Hematopoietic Stem Cell Transplantation Patients With Wiskott-Aldrich Syndrome

NCT00160355

COMPLETED Phase 3

Study of Treatment for Patients With Cancer of the Eye -Retinoblastoma

NCT00186888

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Phase Distribution

PhaseTrial count
Phase 1 87
Phase 2 86
Phase 3 17
Phase 4 2

What is open in the St. Jude Children's Research Hospital pipeline

90 recruiting of 410 indexed (22% open); 227 completed (55%).

Phase mix: 19 late (III/IV) vs 173 early (I/II) (early-phase heavy).

Top condition: Sickle Cell Disease (17 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

St. Jude Children's Research Hospital: open-pipeline peers nationwide

Peers matched on 410 registered trials and 22% open enrollment, not the therapeutic-area sidebar.

St. Jude Children's Research Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0100200300400500 10%15%20%25%30% Total trials Recruiting share St. Jude Children's Research HospitalTakedaUniversity of Kansas Medical CenterRutgers, The State University of New JerseyCase Comprehensive Cancer CenterNorthwell HealthVanda PharmaceuticalsBoston University Charles River CampusRegeneron Pharmaceuticals
St. Jude Children's Research Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

St. Jude Children's Research Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 410 trials (± recruiting share)

Sponsors near 22% open enrollment (± trial volume)

What to do with this St. Jude Children's Research Hospital page

410 registered trials is a research-attention snapshot, not an endorsement of St. Jude Children's Research Hospital or any single study.

  • 90 of St. Jude Children's Research Hospital's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Sickle Cell Disease is the condition St. Jude Children's Research Hospital studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Sickle Cell Disease trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. St. Jude Children's Research Hospital pipeline card: 410 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.