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ClinicalTrials.gov 28 recruiting now early-phase tilt

Hodgkin Lymphoma: early-phase trial registry

28 of 72 indexed Hodgkin Lymphoma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #191 of 28,707 conditions by registered trial count.

72 US clinical trials · 28 currently recruiting · #191 of 28,707 conditions by registered trial count

Hodgkin Lymphoma: 72 US clinical trials tracked, 28 recruiting.

Hodgkin Lymphoma is the subject of 72 registered US clinical trials on ClinicalTrials.gov, 28 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 58 in Phase 1-2 (earlier-stage). The most active sponsor is St. Jude Children's Research Hospital, running 7 of these trials.

Enrollment posture brief

Registry condition hodgkin-lymphoma

OPEN 28 | RECR 39% | LATE 1 | EARLY 58 | RANK #191 | SPON 7

Nearest open-share peer: Chronic Myeloid Leukemia (39% recruiting · 36 trials)

NSCLC66.7%Crohn Disease47.2%Chronic Low Back Pain41.7%Hodgkin Lymphoma (this)39%HIV-1-infection33.3%
Open-enrollment share among volume-matched conditions near Hodgkin Lymphoma

Hodgkin Lymphoma lists 28 open slots (39% of 72 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Hodgkin Lymphoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Hodgkin Lymphoma recruits in line with its size-band peers.

    28 of 72 indexed trials (38.9%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Hodgkin Lymphoma trials is spread across many organizations.

    St. Jude Children's Research Hospital accounts for 7 of 72 trials (9.7%). 46 distinct sponsors appear on at least one study for this condition label.

  3. Most Hodgkin Lymphoma trials plan to enrol fewer than 100 people.

    Median target enrolment is 54 among the 72 trials that report a genuine target (sentinel values excluded). 52 of those (72.2%) plan for fewer than 100 participants.

  4. Hodgkin Lymphoma research is mostly interventional.

    67 interventional and 5 observational studies make up this index (93.1% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 126Phase 232Phase 31

Open and recent trials

72 total, page 1 of 2

RECRUITING 2,000 participants

Evaluating the Impact of Social and Genetic Factors on Outcomes in Adolescent and Young Adult Cancer Survivors

ECOG-ACRIN Cancer Research Group

NCT06002828

RECRUITING Phase 3 1,042 participants

Brentuximab Vedotin in Early Stage Hodgkin Lymphoma

University College, London

NCT04685616

RECRUITING Phase 2 257 participants

Phase II Study of Second- Line Pembrolizumab Plus GVD for Relapsed or Refractory Hodgkin Lymphoma

Memorial Sloan Kettering Cancer Center

NCT03618550

RECRUITING Phase 2 216 participants

CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplant

City of Hope Medical Center

NCT06059391

RECRUITING Phase 2 150 participants

Auto Stem Cell Transplant for Lymphoma Patients

Masonic Cancer Center, University of Minnesota

NCT03125642

RECRUITING NA 140 participants

Lifestyle Intervention of Food and Exercise for Lymphoma Survivors

University of Miami

NCT05839210

RECRUITING Phase 1 110 participants

AZD3470 as Monotherapy and in Combination With Anticancer Agents in Participants With Relapsed/Refractory Haematologic Malignancies.

AstraZeneca

NCT06137144

RECRUITING NA 110 participants

Improving Exercise Capacity With a Tailored Physical Activity Intervention

Wake Forest University Health Sciences

NCT05595577

RECRUITING Phase 2 100 participants

Mozobil for Autologous Hematopoietic Stem Cell Transplantation

Thomas Jefferson University

NCT07188090

RECRUITING Phase 1 90 participants

Constitutive IL7R (C7R) Modified Banked Allogeneic CD30.CAR EBVSTS for CD30-Positive Lymphomas

Baylor College of Medicine

NCT06176690

RECRUITING Phase 2 80 participants

Chemoradiotherapy With Targeted Immunotherapy in Pediatric Lymphoma

New York Medical College

NCT05253495

RECRUITING Phase 1 80 participants

Phase I/II Study of CAR.70- Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Hematological Malignances

M.D. Anderson Cancer Center

NCT05092451

RECRUITING Phase 1 79 participants

Safety and Preliminary Efficacy of MT-601 in Patients With Relapsed/Refractory Lymphoma

Marker Therapeutics

NCT05798897

RECRUITING Phase 1 73 participants

A Phase 1 of CTX-8371 in Patients With Advanced Malignancies

Compass Therapeutics

NCT06150664

RECRUITING Phase 2 71 participants

A Study of BV-AVD in People With Bulky Hodgkin Lymphoma

Memorial Sloan Kettering Cancer Center

NCT06377566

RECRUITING Phase 2 63 participants

Two Step Haplo With Radiation Conditioning

Thomas Jefferson University

NCT05031897

RECRUITING Phase 2 60 participants

Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies

Fred Hutchinson Cancer Center

NCT04195633

RECRUITING Phase 1 54 participants

Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

Therapeutic Advances in Childhood Leukemia Consortium

NCT05476770

RECRUITING Phase 1 54 participants

Nivolumab With Ruxolitinib in Relapsed or Refractory Classical Hodgkin Lymphoma

Veronika Bachanova

NCT03681561

RECRUITING Phase 2 49 participants

A Study of Carmustine With and Without Ethanol in Subjects With Lymphoma

VIVUS

NCT06915246

RECRUITING Phase 2 48 participants

BrECADD Therapy in Stage 2 B-IV Hodgkin Lymphoma

University of Miami

NCT07002216

RECRUITING Phase 2 36 participants

A Phase II Trial of Mosunetuzumab, Polatuzumab, Tafasitamab, and Lenalidomide in Patients With Relapsed B-cell NHL

M.D. Anderson Cancer Center

NCT05615636

RECRUITING Phase 1 31 participants

ATLCAR.CD30.CCR4 for CD30+ HL ATLCAR.CD30.CCR4 Cells

UNC Lineberger Comprehensive Cancer Center

NCT06090864

RECRUITING Phase 1 22 participants

Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors

University of Wisconsin, Madison

NCT02508038

RECRUITING Phase 2 20 participants

ABBA CORD: dCBT w/ Abatacept for aGVHD Prophylaxis

Leland Metheny

NCT06680661

RECRUITING Phase 2 20 participants

AlloSCT for Malignant and Non-malignant Hematologic Diseases Utilizing Alpha/Beta T Cell and CD19+ B Cell Depletion

Mitchell Cairo

NCT04099966

RECRUITING Phase 2 9 participants

Evaluating Combination of Nivolumab and Axatilimab in Patients With Relapsed/Refractory Classical Hodgkin Lymphoma

University of Utah

NCT05723055

RECRUITING Early Phase 1 8 participants

Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT06398457

ACTIVE NOT RECRUITING 1,564 participants

A Longitudinal Assessment of Frailty in Young Adult Survivors of Childhood Cancer

St. Jude Children's Research Hospital

NCT02256137

ACTIVE NOT RECRUITING Phase 2 503 participants

Methionine PET/CT Studies In Patients With Cancer

St. Jude Children's Research Hospital

NCT00840047

ACTIVE NOT RECRUITING 434 participants

Obstructive Sleep Apnea in Survivors of Hodgkin Lymphoma Treated With Thoracic Radiation

St. Jude Children's Research Hospital

NCT03361020

ACTIVE NOT RECRUITING 350 participants

Cardiovascular Reserve Evaluation in Survivors of Transplant, CREST Study

City of Hope Medical Center

NCT04537871

ACTIVE NOT RECRUITING Phase 2 340 participants

Safety and Efficacy of Pembrolizumab (MK-3475) in Children and Young Adults With Classical Hodgkin Lymphoma (MK-3475-667/KEYNOTE-667)

Merck Sharp & Dohme

NCT03407144

ACTIVE NOT RECRUITING Phase 2 232 participants

Pediatric Classical Hodgkin Lymphoma Consortium Study: cHOD17

St. Jude Children's Research Hospital

NCT03755804

ACTIVE NOT RECRUITING NA 118 participants

Brentuximab Vedotin Combined With AVD Chemotherapy in Patients With Newly Diagnosed Early Stage, Unfavorable Risk Hodgkin Lymphoma

Memorial Sloan Kettering Cancer Center

NCT01868451

ACTIVE NOT RECRUITING Phase 2 102 participants

Multi-antigen CMV-MVA Triplex Vaccine in Reducing CMV Complications in Patients Previously Infected With CMV and Undergoing Donor Hematopoietic Cell Transplant

City of Hope Medical Center

NCT02506933

ACTIVE NOT RECRUITING Phase 2 88 participants

Combination Chemotherapy With or Without Radiation Therapy in Treating Young Patients With Favorable-Risk Hodgkin Lymphoma

St. Jude Children's Research Hospital

NCT00846742

ACTIVE NOT RECRUITING Phase 1 83 participants

A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer

GlaxoSmithKline

NCT06521567

ACTIVE NOT RECRUITING Phase 1 82 participants

A(B)VD Followed by Nivolumab as Frontline Therapy for Higher Risk Patients With Classical Hodgkin Lymphoma (HL)

Memorial Sloan Kettering Cancer Center

NCT03033914

ACTIVE NOT RECRUITING Phase 2 69 participants

TCRαβ-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use of Blinatumomab, in Naive T-cell Depleted Haploidentical Donor Hematopoietc Cell Transplantation for Hematologic Malignancies

St. Jude Children's Research Hospital

NCT03849651

ACTIVE NOT RECRUITING Phase 1 67 participants

Study of the Monoclonal Antibody IMT-009 in Patients With Advanced Solid Tumors or Lymphomas

Immunitas Therapeutics

NCT05565417

ACTIVE NOT RECRUITING NA 44 participants

Use of Transcranial Photobiomodulation to Improve Cognition and Self-Reported Outcomes in Survivors of Childhood Cancer

St. Jude Children's Research Hospital

NCT05550948

ACTIVE NOT RECRUITING Phase 1 36 participants

Administration of TAA-Specific CTLs; Hodgkin or Non-Hodgkin Lymphoma; TACTAL

Baylor College of Medicine

NCT01333046

ACTIVE NOT RECRUITING Phase 1 35 participants

Chemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant

Roswell Park Cancer Institute

NCT03192397

ACTIVE NOT RECRUITING NA 35 participants

Integrated Actionable Aging Assessment for Cancer Patients Pilot

University of Colorado, Denver

NCT05871008

ACTIVE NOT RECRUITING Phase 1 34 participants

CMV-MVA Triplex Vaccination of Stem Cell Donors in Preventing CMV Viremia in Participants With Allogeneic Transplant

City of Hope Medical Center

NCT03560752

ACTIVE NOT RECRUITING Phase 1 30 participants

A Clinical Trial of BP1002 in Patients With Advanced Lymphoid Malignancies

Bio-Path Holdings

NCT04072458

ACTIVE NOT RECRUITING NA 30 participants

Radiation Dose Study for Relapsed/Refractory Hodgkin/Non-Hodgkin Lymphoma

University of Chicago

NCT05019976

ACTIVE NOT RECRUITING NA 30 participants

Geriatric Optimization Plan to Improve Survival in Older Adult Allogeneic Hematopoietic Cell Transplant Candidates, OTIS Study

Ohio State University Comprehensive Cancer Center

NCT05972577

ACTIVE NOT RECRUITING Phase 2 25 participants

PET Adapted Brentuximab Vedotin and Pembrolizumab in Combination With Doxorubicin and Dacarbazine in Classic Hodgkin Lymphoma

M.D. Anderson Cancer Center

NCT05922904

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Phase Distribution

PhaseTrial count
Phase 1 26
Phase 2 32
Phase 3 1

Named interventions

Most-linked intervention names on Hodgkin Lymphoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Cyclophosphamide Drug
8 trials
Dacarbazine Drug
5 trials
Nivolumab Drug
5 trials
Doxorubicin Drug
5 trials
Fludarabine Drug
5 trials
Pembrolizumab Drug
5 trials
Multi-peptide CMV-Modified Vaccinia Ankara Vaccine Biological
4 trials
Bleomycin Drug
3 trials

US sites by state

Facility locations filed on Hodgkin Lymphoma trials. A trial with sites in several states counts in each.

California 21 trials
New York 17 trials
Florida 15 trials
Texas 14 trials
Massachusetts 13 trials
Tennessee 10 trials
Illinois 10 trials
Ohio 8 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Hodgkin Lymphoma page

72 registered trials, 28 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Hodgkin Lymphoma condition card totals 72 registered trials; most-linked intervention Cyclophosphamide; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.