National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) sponsors 490 registered US clinical trials on ClinicalTrials.gov, 50 of them currently recruiting, and 398 completed. 69 of these trials are in Phase 3-4 (later-stage) and 178 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 25 trials.
Trial Pipeline
490 total, page 1 of 10
Hepatic Lipid Metabolism-Alcohol Use Disorder
NCT07191561
Ketoconazole Effects on the Daily Cortisol Rhythm in Mild Autonomous Cortisol Secretion
NCT07649317
Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes Mellitus
NCT07142252
Accuracy of 18F-Fluorocholine PET/MR and NeuroEXPLORER PET/CT Imaging for Localization of Parathyroid Tumors
NCT07444723
Youth-Onset Type 2 Diabetes and Heart Disease: The Young at Heart Prospective Cohort Study
NCT06730113
VIR-2218 and Peginterferon Alfa-2a for Chronic Hepatitis B
NCT06092333
Desmopressin Stimulation Test Performance in ACTH-Dependent Cushing Syndrome
NCT06635629
Pilot Study of Isocaloric Time Restricted Eating on Ketone Metabolism and Immunoregulation
NCT06169137
Diet Order Effects of Low Fat vs. Low Carb Diets on Body Fat Change
NCT06325722
Variability In Mixed Meal Tests: Fixed Versus Adjusted to Energy Needs Caloric Dose
NCT06223555
Effect of Nicotinamide Riboside on Ketosis, Fat Oxidation & Metabolic Rate
NCT06044935
Feasibility of Adipose Tissue Triglyceride (TG) Labelling in Familial Partial Lipodystrophy (FPLD)
NCT05996536
Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United States
NCT05832229
The Effects of Increasing Caloric Intake on Diet-Induced Thermogenesis and 24h Energy Expenditure
NCT05545306
Unraveling the Mechanisms Underlying Primary Sclerosing Cholangitis Through a Multidisciplinary, Integrative Research Approach
NCT04685200
Study of Growth Hormone Inhibition Using Pegvisomant in Severe Insulin Resistance
NCT05470504
A Natural History Study of Metabolic Sizing in Health and Disease
NCT05398783
Natural History of Pregnancy and Pregnancy Outcomes in Metreleptin-Treated vs Untreated Subjects With Lipodystrophy
NCT05419037
Fontan Associated Liver Disease and the Evaluation of Biomarkers for Disease Severity Assessment
NCT05213598
Early Tracking of Childhood Health Determinants (ETCHED) Study
NCT03481829
Developing Biomarkers of Dietary Intake: Dose Dependent Measurement of Sugar Intake
NCT04799301
TReatment for ImmUne Mediated PathopHysiology
NCT04862221
Evaluation of Patients With Gastrointestinal Disease
NCT05041374
Natural History Study of Parathyroid Disorders
NCT04969926
The Role of 68-Gallium-DOTATATE-PET/CT in the Imaging of Metastatic Thyroid Cancer
NCT04927416
The Use of 124-I-PET/CT Whole Body and Lesional Dosimetry in Differentiated Thyroid Cancer
NCT03841617
Non-Alcoholic Fatty Liver Disease, the HEpatic Response to Oral Glucose, and the Effect of Semaglutide (NAFLD HEROES)
NCT03884075
Study of Endocrine-Related Conditions and Physiology
NCT03867448
Clinical and Molecular Characteristics of Primary Aldosteronism in Blacks
NCT03374215
The Physiological Responses and Adaptation of Brown Adipose Tissue to Chronic Treatment With Beta3-Adrenergic Receptor Agonists
NCT03049462
Evaluation of Adults With Endocrine and Metabolic-Related Conditions
NCT02830308
Molecular, Cellular, and Genetic Characterization of Human Adipose Tissue and Its Role in Metabolism
NCT02692885
Natural History of Noncirrhotic Portal Hypertension
NCT02417740
Prospective Evaluation of 68Ga-DOTATATE PET/CT, Octreotide and F-DOPA PET Imaging in Ectopic Cushing Syndrome
NCT02019706
New Heart Imaging Techniques to Evaluate Possible Heart Disease
NCT01399385
Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy
NCT00977977
Clinical and Genetic Studies in Familial Non-medullary Thyroid Cancer
NCT01109420
Effects of Brain Stimulation on Food Intake and Behavioral Weight Loss Treatment
NCT00739362
Natural History of Familial Carcinoid Tumor
NCT00646022
Blood Sampling for Research Related to Sickle Cell Disease
NCT00542230
Physical and Behavioral Traits of Overweight and Obese Adults
NCT00428987
Urinary Vitamin C Loss in Diabetic Subjects
NCT00071526
Family Investigation of Nephropathy and Diabetes (F.I.N.D.)
NCT00342927
Diabetes and Heart Disease Risk in Blacks
NCT00001853
Immune System Related Kidney Disease
NCT00001979
Evaluation of Patients With Liver Disease
NCT00001971
Diagnosing and Treating Low Blood Sugar Levels
NCT00001276
Studies on Tumors of the Thyroid
NCT00001160
Natural History of Thyroid Function Disorders
NCT00001159
Genetic Studies of Insulin and Diabetes
NCT00001987
What the Pipeline for National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Shows
According to the ClinicalTrials.gov registry, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is linked to 490 US clinical trials across every stage of research activity. Of those, 50 studies are currently recruiting, about 10% of the sponsor's indexed portfolio, and 398 are already marked complete, representing roughly 81% of the total.
The phase mix for National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) reports 69 late-stage studies (Phase 3 and Phase 4 combined) and 178 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is Obesity with 25 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.