Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

RECRUITING Phase 2

Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United States

NCT05832229 · View on ClinicalTrials.gov ↗

Study Summary

This is a double-blind, phase 2 study to evaluate safety and efficacy of rosuvastatin in comparison to placebo after 2 years in patients with compensated cirrhosis.

Interventions

  • DRUG Rosuvastatin

Study Locations (13)

California

  • University of California San Diego NAFLD Research Center — La Jolla
  • Keck Medical Center of USC — Los Angeles
  • LAC + USC Medical Center — Los Angeles
  • UCSF/Zuckerberg San Francisco General Hospital and Trauma Center — San Francisco
  • UCSF Medical Center — San Francisco

New York

  • New York Presbyterian/Weill Cornell — New York
  • Columbia University Iriving School of Medicine — New York

Florida

  • University of Miami Health System — Miami

Michigan

  • University of Michigan — Ann Arbor

Minnesota

  • Mayo Clinic — Rochester

North Carolina

  • Duke Liver Center — Durham

Ohio

  • Cleveland Clinic — Cleveland

Virginia

  • Virginia Commonwealth University — Richmond

Trial Details

FieldValue
Enrollment Target 256 participants
Start Date 2023-12-07
Est. Completion 2029-08-31
Phase Phase 2

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05832229

The ClinicalTrials.gov registry entry for NCT05832229 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 256 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which has 375 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 8 conditions, with Cirrhosis appearing as the primary indexed condition, and to 1 intervention — of which Rosuvastatin is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05832229 reports 13 study locations spanning 8 distinct geographic areas — top geographies include California, New York, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05832229 about?

NCT05832229 is a clinical study titled "Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United States". This is a double-blind, phase 2 study to evaluate safety and efficacy of rosuvastatin in comparison to placebo after 2 years in patients with compensated cirrhosis.

What is the current status of trial NCT05832229?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 256 participants. The study started on 2023-12-07. Estimated completion is 2029-08-31.

What conditions does trial NCT05832229 study?

This clinical trial studies the following conditions: Cirrhosis, Cirrhosis, Liver, Cirrhosis Early, Cirrhosis Due to Hepatitis B, Cirrhosis Advanced. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05832229?

The interventions under investigation include: Rosuvastatin (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05832229?

This trial is sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which has 375 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05832229 being conducted?

This trial has 13 study locations across California, Florida, Michigan, Minnesota, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial