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NCT05996536 · ClinicalTrials.gov registry record
Feasibility of Adipose Tissue Triglyceride (TG) Labelling in Familial Partial Lipodystrophy (FPLD)
A clinical trial of Lipodystrophy, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
- Recruiting
- Registry status
- 14
- Enrollment target
- 1
- Study location
NCT05996536: Recruiting study of Lipodystrophy, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
NCT05996536 is a study of Lipodystrophy that is actively recruiting participants, run by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The registered enrollment target is 14 participants, below the 132-participant average among 11 other Lipodystrophy trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05996536, a study of Lipodystrophy, is actively recruiting participants, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
- RECRUITING
- Registry status
- 14 participants
- Enrollment target
- 1
- Study location
Study Summary
Background: People with familial partial lipodystrophy (FPLD) do not store fat in the body normally. This can lead to serious illnesses such as diabetes and heart disease. To learn more about FPLD, researchers want to compare the fat tissue in people with this disease to the fat tissue of healthy people. Objective: To collect and analyze samples of fat tissue in people with and without FPLD. Eligibility: People aged 18 to 65 years with FPLD. Healthy adults are also needed. Design: Participants will be screened. They will have a physical exam. The size and shape of their body will be measured. They will have an imaging scan to measure their bones, muscle, and fat. Participants will be given heavy water to drink at home. The water contains a tracer to help measure the fat in their blood. They will drink 1 vial 3 times a day. After drinking the water for 9 days, participants will come to the clinic for a 3-day stay. They will eat only foods provided by the hospital; the foods will contain tracers. A needle will be inserted into a vein in the arm; participants will receive infusions of other tracers through this needle into their blood; this needle will also be used to draw blood samples for testing. On their third day in the clinic, participants will have biopsies: Small samples of fat will be removed from under the skin on the belly and thigh. Participants may return for a follow-up visit 8 days after leaving the clinic. Blood draws and fat tissue biopsies will be repeated.
Primary Outcome
Mass of adipose tissue obtained from each biopsy.
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 14 participants |
| Start Date | 2024-01-03 |
| Est. Completion | 2026-06-01 |
What NCT05996536 shows while recruiting
NCT05996536 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 14 participants, a relatively small participant target, below the 132-participant average among 11 other Lipodystrophy trials with a reported enrollment target (89% lower).
The record links to 1 condition, with Lipodystrophy appearing as the primary indexed condition, and to 0 interventions.
NCT05996536 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT05996536 about?
NCT05996536 is a clinical study titled "Feasibility of Adipose Tissue Triglyceride (TG) Labelling in Familial Partial Lipodystrophy (FPLD)". Background: People with familial partial lipodystrophy (FPLD) do not store fat in the body normally. This can lead to serious illnesses such as diabetes and heart disease. To learn more about FPLD, researchers want to compare the fat tissue in people with this disease to the fat tissue of healthy p...
What is the current status of trial NCT05996536?
This trial is currently recruiting. The enrollment target is 14 participants. The study started on 2024-01-03. Estimated completion is 2026-06-01.
What conditions does trial NCT05996536 study?
This clinical trial studies the following conditions: Lipodystrophy.
Who is sponsoring clinical trial NCT05996536?
This trial is sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which has 490 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05996536 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05996536's enrollment target sits among peer trials
14 11th of 11 higher than 1 of 11 other Lipodystrophy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Lipodystrophy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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