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Liver Disease clinical trials
Every US clinical trial registered for Liver Disease — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
15 US clinical trials · 1 currently recruiting
The research picture
Liver Disease has 15 registered US clinical trials, 1 of them open to new participants right now — about 7% of the total.
- 1
- recruiting participants now
- 7%
- of trials open to enrollment
- 2
- in Phase 3–4 (later-stage)
- 5
- top sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Evaluation of Patients With Liver Disease
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00001971
Genetic Modifiers of Cystic Fibrosis (CF) Liver Disease
University of North Carolina, Chapel Hill
NCT00804583
Quantitative Evaluation of the Progression of Liver Disease, Using ShearWaveTM
Baylor Research Institute
NCT02070315
Genetics of Hepatitis C Virus Infection
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00005657
Pediatric Liver Database
Medical College of Wisconsin
NCT00677625
Alternate Dosing Study of MK-6024 in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) (MK-6024-016)
Merck Sharp & Dohme
NCT06482112
Dynamic Post-Prandial Metabolism in Patients With Non-Alcoholic Fatty Liver Disease
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT02520609
Prospective Validation of a Plasma Transfusion Dosing Algorithm in Patients With Chronic Liver Disease
University of Colorado, Denver
NCT02366845
Hepatic Impairment Study
Bayer
NCT00829231
Comparing Pain in Patients Undergoing Percutaneous Versus Transjugular Techniques of Liver Biopsy
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT02311348
Elafibranor Pharmacokinetic Parameters in Hepatic Impaired Patients
Genfit
NCT03765671
Study to Compare Conivaptan in Subjects With Mild & Moderate Liver Impairment Versus Subjects With Normal Liver Function
Cumberland Pharmaceuticals
NCT00851227
A Phase 1 Study to Compare the PK and Safety of Naproxcinod in Hepatic Impaired Patients and Matching Healthy Subjects
NicOx
NCT00621881
Non-invasive Biomarkers of Fibrosis in Pediatric Liver Diseases
Baylor College of Medicine
NCT01988753
Gabapentin to Treat Itch in Patients With Liver Disease
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00058890
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 4 |
| Phase 2 | 1 |
| Phase 3 | 1 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Liver Disease Trial Landscape
ClinicalTrials.gov lists 15 US studies indexed under Liver Disease, and 1 of those are currently open to recruitment — roughly 7% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Liver Disease shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 5 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Liver Disease is led by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) with 5 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 15 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Liver Disease?
PlainTrial tracks 15 US clinical trials for Liver Disease, of which 1 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Liver Disease?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.