National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) sponsors 490 registered US clinical trials on ClinicalTrials.gov, 50 of them currently recruiting, and 398 completed. 69 of these trials are in Phase 3-4 (later-stage) and 178 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 25 trials.
Trial Pipeline
490 total, page 2 of 10
Rituximab-pvvr and Abatacept vs Rituximab-pvvr Alone in New Onset Type 1 Diabetes
NCT03929601
Janus Kinase (JAK) Inhibitors to Preserve C-Peptide Production in New Onset Type 1 Diabetes (T1D)
NCT05743244
People With CHC Who Achieved a Sustained Virological Response Following Therapy With Direct Acting Antiviral Agents
NCT03520660
Compassionate Use of Metreleptin in Previously Treated People With Partial Lipodystrophy
NCT02262806
Compassionate Use of Metreleptin in Previously Treated People With Generalized Lipodystrophy
NCT02262832
Effect of Metreleptin Therapy in the Treatment of Severe Insulin Resistance
NCT00085982
Platform Trial in Stage 1 Diabetes: Comparing Golimumab vs Placebo
NCT07683026
Platform Trial to Delay Stage 3 Diabetes: Comparing Teplizumab With ATG
NCT07216391
177Lu-DOTA-EB-TATE in Adult Patients With Metastatic, Radioactive Iodine Non-Responsive Oncocytic (Hurthle-Cell) Thyroid Cancer
NCT06991738
Evaluation of the Clinical Spectrum of Diabetes and Obesity in Youth and Adults
NCT07388537
Prevalence and Development of Liver Dysfunction in Hematopoietic Stem Cell Transplant
NCT05722210
Effects of Meal Macronutrients on Postprandial Lipids
NCT07313787
Trial of the Combination of Alpha-Lipoic Acid and Mirabegron in Women and in Men With Obesity
NCT05713799
Assessing the Impact of Perceptions of Unpredictability on Objective Measures of Food Consumption and Metabolism
NCT06690294
Discovering Determinants of Food Intake by Application of Artificial Intelligence to Complex, High-Dimensional Data
NCT07637656
Longitudinal Immunophenotyping of Patients With Inflammatory Bowel Disease
NCT07619547
STOP-T1D Low-Dose (ATG)
NCT04291703
Study to Determine the Response to COVID-19 Vaccination and Prevalence of COVID-19 in Subjects With Chronic Liver Disease
NCT05669677
Effect of Ultra-processed Versus Unprocessed Diets on Energy Metabolism
NCT05290064
The Impact of the COVID-19 Pandemic on Eating Behavior and Weight Change
NCT04896060
Vitamin E Dosing Study
NCT04801849
HOPE Consortium Trial to Reduce Pain and Opioid Use in Hemodialysis
NCT04571619
A Multiple Ascending Dose Trial Investigating Safety, Tolerability and Pharmacokinetics of NNC0361-0041
NCT04279613
Prebiotics and Metformin Improve Gut and Hormones in Type 2 Diabetes in Youth (MIGHTY-fiber)
NCT04209075
Famine From Feast: Linking Vitamin C, Red Blood Cell Fragility, and Diabetes
NCT02107976
Effects of Low Fat Versus Low Carbohydrate Diets on Energy Metabolism
NCT03878108
Losartan for the Treatment of Pediatric NAFLD
NCT03467217
Brain Dopamine Function in Human Obesity
NCT03648892
Hydroxychloroquine in Individuals At-risk for Type 1 Diabetes Mellitus
NCT03428945
Treatment of Chronic Delta Hepatitis With Lonafarnib, Ritonavir and Lambda Interferon
NCT03600714
Effect of Ultra Processed Versus Unprocessed Diets on Energy Intake
NCT03407053
Effect of Isocaloric Ultra Processed Versus Unprocessed Diets on Insulin Sensitivity
NCT03189121
Hepatitis B Reactivation During Treatment With Direct-Acting Antiviral Agents for Chronic Hepatitis C Infection
NCT03248622
Title: Therapeutic Targets in African-American Youth With Type 2 Diabetes
NCT02960659
Food Intake Response to Short-Term Modifications of Metabolism in Humans
NCT02939404
Longitudinal Assessment of Transient Elastography in Cystic Fibrosis
NCT03001388
MRI to Characterize and Predict CF Liver Disease in PUSH Cohort
NCT02979340
Optimizing HBV Care Cascade Among Foreign-Born in the United States (FOCUS-HBV Study)
NCT05621304
A Phase 1 Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ManNAc in Subjects With Primary Podocyte Diseases
NCT02639260
Immune Effects of Oral Insulin in Relatives at Risk for Type 1 Diabetes Mellitus (TN20)
NCT02580877
Efficacy, Safety and Tolerability of ISIS 304801 in People With Partial Lipodystrophy With an Open-Label Extension
NCT02639286
Dynamic Post-Prandial Metabolism in Patients With Non-Alcoholic Fatty Liver Disease
NCT02520609
Quantifying the Persistence of Metabolic Adaptation and Weight Regain Following Extreme Weight Loss
NCT02544009
Treatment of Chronic Delta Hepatitis With Lonafarnib and Ritonavir
NCT02511431
Viral Kinetics, Interferon Stimulated Genes (ISGs) and mirRNA Among Subjects Infected With Different Hepatitis C Virus Genotypes During Therapy With Sofosbuvir and GS-5816
NCT02468648
Deciphering the Mechanisms Involved in Microbial Translocation Across the Spectrum of HCV Associated Liver Fibrosis
NCT02400216
Thyroid Hormone to Induce Non-Insulin Mediated Glucose Disposal in People With Insulin Receptor Mutations
NCT02457897
Palmitate Breath Test to Assess Fatty Acid Oxidation in Non Alcoholic Fatty Liver Disease (NAFLD)
NCT02363309
Add-on Peginterferon Following Nucleos(t)Ide Analogue Treatment
NCT02364336
Cross Calibration of Two Dual Energy Densitometers and Comparison of Regional Adipose Tissue Measurements by iDXA and MRI
NCT02346474
What the Pipeline for National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Shows
According to the ClinicalTrials.gov registry, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is linked to 490 US clinical trials across every stage of research activity. Of those, 50 studies are currently recruiting, about 10% of the sponsor's indexed portfolio, and 398 are already marked complete, representing roughly 81% of the total.
The phase mix for National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) reports 69 late-stage studies (Phase 3 and Phase 4 combined) and 178 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is Obesity with 25 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.