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NCT06730113 · ClinicalTrials.gov registry record
Youth-Onset Type 2 Diabetes and Heart Disease: The Young at Heart Prospective Cohort Study
A clinical trial of Obesity and Type 2 Diabetes, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
- Recruiting
- Registry status
- 930
- Enrollment target
- 2
- Study locations
NCT06730113: Recruiting study of Obesity and Type 2 Diabetes, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
NCT06730113 is a study of Obesity and Type 2 Diabetes that is actively recruiting participants, run by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The registered enrollment target is 930 participants, above the 818-participant average among 1,053 other Obesity trials with a reported enrollment target (14% higher). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06730113, a study of Obesity and Type 2 Diabetes, is actively recruiting participants, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
- RECRUITING
- Registry status
- 930 participants
- Enrollment target
- 2
- Study locations
Study Summary
Background: Type 2 diabetes is a disease that affects blood sugar levels. Complications can include heart and blood vessel (vascular) diseases. Rates of type 2 diabetes have tripled in children and young adults over the last 40 years. Vascular diseases are also increasing in young people. Objective: To learn more about factors, including type 2 diabetes, that may cause vascular disease in young people. Eligibility: People aged 12 to 25 years who (1) have type 2 diabetes; (2) are overweight but not diabetic; (3) or are lean and healthy. Biological parents are also needed. Design: Young participants will visit the NIH clinic once a year for up to 25 years. Each visit will take 4 days. Before each visit, participants will wear devices to track their sleep, activity, and blood sugar levels for 7 to 10 days. At each visit, participants will have tests including: Samples: They will provide blood, urine, and stool samples. Heart: They will ride a stationary bike for 6 minutes with stickers applied to their chest. Scans: They will lie on a bed that slides into a tube; the machine will take pictures of the inside of their body. Energy: They will wear a hood over their head to measure the air they breathe. Social stress: They will give a speech for 10 minutes to show their body s response to stress. Glucose: They will drink a sweet drink to see how their blood sugar changes. Biological parents will have 1 study visit. They will have blood tests. They will fill in questionnaires about their lifestyle and stress. ...
Primary Outcome
Carotid-femoral pulse wave velocity (m/s) measured with SphygmaCor, higher numbers indicated greater arterial stiffness
Conditions Studied
Study Locations (2)
District of Columbia
- Children's National Hospital (CNH) - Washington D.C.
Maryland
- National Institutes of Health Clinical Center - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 930 participants |
| Start Date | 2025-03-12 |
| Est. Completion | 2033-10-31 |
What NCT06730113 shows while recruiting
NCT06730113 is an observational study that tracks outcomes without assigning an intervention. The registered 930 participants enrollment target is mid-sized for trials with a published cap, above the 818-participant average among 1,053 other Obesity trials with a reported enrollment target (14% higher).
The record links to 2 conditions, with Obesity appearing as the primary indexed condition, and to 0 interventions.
NCT06730113 reports a single indexed study location in District of Columbia, Maryland.
Frequently Asked Questions
What is clinical trial NCT06730113 about?
NCT06730113 is a clinical study titled "Youth-Onset Type 2 Diabetes and Heart Disease: The Young at Heart Prospective Cohort Study". Background: Type 2 diabetes is a disease that affects blood sugar levels. Complications can include heart and blood vessel (vascular) diseases. Rates of type 2 diabetes have tripled in children and young adults over the last 40 years. Vascular diseases are also increasing in young people. Objectiv...
What is the current status of trial NCT06730113?
This trial is currently recruiting. The enrollment target is 930 participants. The study started on 2025-03-12. Estimated completion is 2033-10-31.
What conditions does trial NCT06730113 study?
This clinical trial studies the following conditions: Obesity, Type 2 Diabetes.
Who is sponsoring clinical trial NCT06730113?
This trial is sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which has 490 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06730113 being conducted?
This trial has 2 study locations across District of Columbia, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06730113's enrollment target sits among peer trials
930 79th of 1053 higher than 975 of 1,053 other Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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