H. Lee Moffitt Cancer Center and Research Institute

502 total trials 82 currently recruiting 280 completed

H. Lee Moffitt Cancer Center and Research Institute sponsors 502 registered US clinical trials on ClinicalTrials.gov, 82 of them currently recruiting, and 280 completed. 5 of these trials are in Phase 3-4 (later-stage) and 335 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Prostate Cancer, with 12 trials.

Trial Pipeline

502 total, page 1 of 11

RECRUITING Phase 2

Trial of Therapies With IT cDC1s Combined w/ IT Trastuzamab for Her+ or IT Nivolumab for Her- BC LMD

NCT07694986

RECRUITING NA

Testing an MBI for Smoking Cessation and Alcohol Use Among Cancer Survivors

NCT07447635

RECRUITING Phase 2

Phase 2a Study of High-Dose Testosterone Followed by Radioligand Therapy in mCRPC

NCT07476001

RECRUITING Phase 3

Phase III Trial of Brain MRI Surveillance in Stage IV Breast Cancer

NCT07357298

RECRUITING Phase 1

Metastatic Ewing's Trial Testing Schedule Enhancement to Improve Outcomes

NCT07194044

RECRUITING Phase 2

Digoxin Medulloblastoma Study

NCT06701812

RECRUITING Phase 1

Clinical Trial of CD40L-augmented TIL for Patients With Advanced Melanoma

NCT06961357

RECRUITING Phase 1

Asciminib Maintenance Therapy Following alloHCT or CAR T to Prevent Relapse in Adults With Ph+ALL

NCT07250087

RECRUITING Phase 2

Phase 2 Combination of Melphalan/HDS Via PHP + Tebentafusp in Treating Metastatic Uveal Melanoma

NCT07276386

RECRUITING NA

Hybrid Effectiveness-Implementation Trial to Integrate Precision Skin Cancer Risk Feedback in FQHCs

NCT07222995

RECRUITING

A First-in-Human Study of FID-022 in Solid Tumor Patients

NCT07249775

RECRUITING Phase 1

Ropeginterferon in Patients w/Cutaneous T-Cell Lymphoma (CTCL)

NCT07047885

RECRUITING

Predictors of Health-Related QOL in Adults With CLL or Small Lymphocytic Lymphoma

NCT07030400

RECRUITING NA

The MIND-BC Study: MIND Diet for Breast Cancer Cognition

NCT07018986

RECRUITING Phase 2

Pembrolizumab for Advanced Cutaneous Sarcomas Not Including Angiosarcoma

NCT07007273

RECRUITING Phase 2

Prospective Trial Assessing Real World Outcomes Response to Pembro in Black Patients w/ NSCLC

NCT06745882

RECRUITING Phase 1

Tumor Infiltrating Lymphocyte Therapy for Pediatric High Risk Solid Tumors

NCT06047977

RECRUITING Phase 2

Elranatamab Post Cilta-cel in Patients With Clinical High Risk Relapsed Myeloma

NCT06947083

RECRUITING NA

ProSalud in Latinos Living in Rural/Agricultural Communities Within Moffitt's Catchment Area

NCT07218848

RECRUITING NA

Creation of an Infrastructure to Support Delivery of mHealth Interventions for Cancer Patients

NCT06909357

RECRUITING Phase 2

Ph II Study of Enfortumab Vedotin in Patients With Advanced or Metastatic CRC or HCC

NCT06553885

RECRUITING Phase 2

Tafasitamab and Lenalidomide as First Salvage Therapy for Residual Large B Cell Lym

NCT06760156

RECRUITING Phase 2

Phase II Study of Neoadjuvant Cetuximab and Cemiplimab in Patients Undergoing Surgery for HNSCC

NCT06855212

RECRUITING Phase 2

Phase II Study of Systemic Screening in Pathologic Node Positive Breast Cancer

NCT06833502

RECRUITING Phase 2

Ruxolitinib vs Prednisone as First-line Therapy for cGVHD Needing Systemic Therapy

NCT06660355

RECRUITING Phase 1

Sacituzumab Govitecan and Zimberelimab w/SRS in the Management of Metastatic Triple Negative Breast Cancer With Brain Metastases

NCT06238921

RECRUITING Phase 2

BCL2i CLAG-M in R/R Acute Myeloid Leukemia

NCT06660368

RECRUITING Phase 2

Discontinuation of Hypomethylating Agent and Venetoclax in Patients With AML MRD

NCT06511882

RECRUITING Phase 2

Study of Cemiplimab Plus Ziv-Aflibercept for Subjects With Metastatic Uveal Melanoma

NCT06121180

RECRUITING Phase 1

Immunologic Targeting of ESR1 Receptor for Hormone Receptor Expressing Metastatic Breast Cancer

NCT06691035

RECRUITING Phase 1

Autologous Gamma Delta T Cells to Target Prostate Stem Cell Antigen in mCRPC

NCT06193486

RECRUITING NA

Multilevel Action Toward Colorectal Cancer and Hepatitis C Education and Screening

NCT06745895

RECRUITING Phase 2

A Phase II Study of ACR-368 and Low Dose Gemcitabine in R/M HNSCC

NCT06597565

RECRUITING NA

Working Through Outreach, Navigation and Digital Enabled Referral and Recruitment Strategies (ACT WONDER²S)

NCT06560398

RECRUITING Phase 2

Phase 2 Open Label Randomized Study of Pirtobrutinib and Brexucabtagene Autoleucel in R/R MCL

NCT06553872

RECRUITING Phase 2

Sequential Therapies Modeled on Evolutionary Dynamics for Breast Cancer

NCT06409390

RECRUITING NA

Support Through Remote Observation and Nutrition Guidance Program for Individuals With Gastroesophageal Cancer

NCT06497569

RECRUITING Early Phase 1

Personalized Dendritic Cell Vaccine Pilot for High Risk TNBC After Neoadjuvant Therapy

NCT06435351

RECRUITING Phase 2

App for Reducing Cravings to Smoke

NCT06088498

RECRUITING NA

Exercise Prehabilitation for Locoregional Esophageal Cancer

NCT06430346

RECRUITING Phase 2

Neoadjuvant and Adjuvant Anti-PD1 or Combinations for Locoregionally Advanced Melanoma

NCT06295159

RECRUITING

Generating Novel Translational and Therapeutic Strategies Based on a Multicenter, Pediatric and AYA Evolutionary Tumor Board (pedsETB)

NCT06423950

RECRUITING Phase 2

Rituximab and Zanubrutinib in Patients With Indolent B-cell Lymphomas

NCT06350318

RECRUITING NA

High-Fermented Food Intervention Among Locally Advanced Rectal Cancer Patients (The FEED Trial)

NCT06337552

RECRUITING Phase 1

Avapritinib With Decitabine in Patients With SM-AHN

NCT06327685

RECRUITING NA

Remote Exercise and Nutritional Prehabilitation for Pancreatic Cancer

NCT06423963

RECRUITING

Biomarker Approach to Screening for the Early Detection of HPV-related Oropharyngeal Cancer (BASH OPC)

NCT06305676

RECRUITING Phase 2

Neratinib In Combination With Chemotherapy/Trastuzumab/Pembrolizumab In HER2 Gastroesophageal Cancer

NCT06109467

RECRUITING Phase 2

Study of KTE-X19 in Minimal Residual Disease (MRD) Positive B-Cell Acute Lymphoblastic Leukemia (B-ALL)

NCT06144606

RECRUITING Phase 2

Single-Arm Comprehensive Ablative Bridging Irradiation I Prior to CD19 CAR-T In High-Risk R/R LBCL

NCT06104592

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Phase Distribution

PhaseTrial count
Phase 1 167
Phase 2 168
Phase 3 3
Phase 4 2

What the Pipeline for H. Lee Moffitt Cancer Center and Research Institute Shows

According to the ClinicalTrials.gov registry, H. Lee Moffitt Cancer Center and Research Institute is linked to 502 US clinical trials across every stage of research activity. Of those, 82 studies are currently recruiting, about 16% of the sponsor's indexed portfolio, and 280 are already marked complete, representing roughly 56% of the total.

The phase mix for H. Lee Moffitt Cancer Center and Research Institute reports 5 late-stage studies (Phase 3 and Phase 4 combined) and 335 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for H. Lee Moffitt Cancer Center and Research Institute is Prostate Cancer with 12 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.