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ClinicalTrials.gov 4 recruiting now official registry

Fatty Liver clinical trials

4 of 21 indexed Fatty Liver trials are currently recruiting.

21 US clinical trials · 4 currently recruiting

Fatty Liver is the subject of 21 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), running 6 of these trials.

The research picture

Fatty Liver has 21 registered US clinical trials, 4 of them open to new participants right now, about 19% of the total.

4
recruiting participants now
19%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
6
top sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Phase 13Phase 23Phase 31

Active & Recent Trials

21 total, page 1 of 1

RECRUITING 1,500 participants

Early Tracking of Childhood Health Determinants (ETCHED) Study

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT03481829

RECRUITING 1,000 participants

Blood Collection Biorepository for Liver Disease Research

State University of New York at Buffalo

NCT03025074

RECRUITING 300 participants

Exploratory Analysis of Enhanced Liver Function (ELF) Test to Detect Early Fatty Liver in High Risk Population

Methodist Health System

NCT06225193

RECRUITING NA 25 participants

Intermittent Fasting for NAFLD in Adults

Massachusetts General Hospital

NCT04899102

ACTIVE NOT RECRUITING Phase 2 219 participants

Ph 2 Study of the Safety and Efficacy of Three HU6 Dose Levels and Placebo in Nonalcoholic Steatohepatitis

Rivus Pharmaceuticals

NCT05979779

COMPLETED 400 participants

Prevalence of Nonalcoholic Fatty Liver Disease (NAFLD) and Nonalcoholic Steatohepatitis (NASH) Utilizing Ultrasound and Percutaneous Liver Biopsy

Brooke Army Medical Center

NCT01100398

COMPLETED Phase 3 173 participants

Treatment of Nonalcoholic Fatty Liver Disease in Children (TONIC)

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT00063635

COMPLETED NA 111 participants

Study to Assess the Relationship Between Daily Dosing of NRPT and Changes in Liver Fat in Healthy Volunteers

Elysium Health

NCT03513523

COMPLETED 74 participants

Palmitate Breath Test to Assess Fatty Acid Oxidation in Non Alcoholic Fatty Liver Disease (NAFLD)

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT02363309

COMPLETED NA 60 participants

Low Fat Vegan or American Heart Association Diets & Cardiovascular Risk in Obese 9-18 y.o. With Elevated Cholesterol

The Cleveland Clinic

NCT01817491

COMPLETED NA 56 participants

Evaluation of Diet and Exercise in Patients With Non-Alcoholic Fatty Liver Disease

San Antonio Military Medical Center

NCT00815009

COMPLETED 54 participants

Evaluation of Liver and Cardiometabolic Health Benefits on Low Carbohydrate Ketogenic Diet

Virginia Commonwealth University

NCT03141008

COMPLETED 53 participants

Dynamic Post-Prandial Metabolism in Patients With Non-Alcoholic Fatty Liver Disease

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT02520609

COMPLETED Phase 1 50 participants

Vitamin E Pharmacokinetics and Biomarkers in Normal and Obese Women

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT00862433

COMPLETED Phase 2 37 participants

Polyunsaturated Fatty Acids (PUFA) in Diabetic Fatty Liver

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT00323414

COMPLETED NA 26 participants

Impact of Almond Supplementation on Body Composition in Overweight/Obese Minority Adults

Columbia University

NCT02347007

COMPLETED NA 22 participants

Relation of Obesity With Frequency of Meals (MST 0557)

Rockefeller University

NCT00229255

COMPLETED 22 participants

Effect of Fatty Liver on TCA Cycle Flux and the Pentose Phosphate Pathway

University of Texas Southwestern Medical Center

NCT03480594

COMPLETED Phase 2 21 participants

An Evaluation of the Safety and Efficacy of Nitazoxanide on Collagen Turnover in NASH Patients With Fibrosis

Pinnacle Clinical Research, P

NCT03656068

COMPLETED Early Phase 1 9 participants

Liver Positron Emission Tomography (PET) Study of Non Alcoholic Fatty Liver Disease

Washington University School of Medicine

NCT00949403

COMPLETED Phase 1 5 participants

Study of Gemcabene in Adults With FPLD

Elif Oral

NCT03508687

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 3
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Fatty Liver Trial Landscape

21 indexed Fatty Liver studies · 4 recruiting (19%).

Phase mix: 1 late (III/IV) vs 6 early (I/II).

Top sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (6 trials), 9 others listed. 21 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Fatty Liver?

PlainTrial tracks 21 US clinical trials for Fatty Liver, of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Fatty Liver?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.