Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Diabetes Mellitus: full-pipeline trial registry
49 of 210 indexed Diabetes Mellitus trials are currently recruiting.
Corpus placement: #44 of 28,707 conditions by registered trial count.
210 US clinical trials · 49 currently recruiting · #44 of 28,707 conditions by registered trial count
Diabetes Mellitus: 210 US clinical trials tracked, 49 recruiting.
Diabetes Mellitus is the subject of 210 registered US clinical trials on ClinicalTrials.gov, 49 of them currently open to new participants. 26 are in Phase 3-4 (later-stage) and 32 in Phase 1-2 (earlier-stage). The most active sponsor is Takeda, running 8 of these trials.
Enrollment posture brief
Registry condition diabetes-mellitus
OPEN 49 | RECR 23% | LATE 26 | EARLY 32 | RANK #44 | SPON 8
Volume-matched condition peers
Nearest open-share peer: Alzheimers Disease (23% recruiting · 150 trials)
Diabetes Mellitus lists 49 open slots (23% of 210 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Diabetes Mellitus on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
-
Diabetes Mellitus is recruiting below its size-band peers.
49 of 210 indexed trials (23.3%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
-
Sponsorship of Diabetes Mellitus trials is spread across many organizations.
Takeda accounts for 8 of 210 trials (3.8%). 123 distinct sponsors appear on at least one study for this condition label.
-
Typical Diabetes Mellitus enrolment sits around 136 participants.
Median target enrolment is 136 among the 209 trials that report a genuine target (sentinel values excluded). 86 of those (41.1%) plan for fewer than 100 participants.
-
Diabetes Mellitus research is mostly interventional.
175 interventional and 35 observational studies make up this index (83.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
210 total, page 1 of 5
Family Investigation of Nephropathy and Diabetes (F.I.N.D.)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00342927
The T1D Exchange Registry
T1D Exchange, United States
NCT04629586
Examining Digital Health Care Delivery Models Through Medicaid Collaborative
OSF Healthcare System
NCT05555095
Wolfram Syndrome and WFS1-related Disorders International Registry and Clinical Study
Washington University School of Medicine
NCT02841553
Genetics Of Autoimmunity In Type I Diabetes
Medical College of Wisconsin
NCT03648918
Rare and Atypical Diabetes Network
University of South Florida
NCT05544266
Early Tracking of Childhood Health Determinants (ETCHED) Study
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT03481829
Genetic Studies of Insulin and Diabetes
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00001987
Comparing Healthcare Visit Recording and Open Notes to Improve Chronic iLlness Care Experience in Older Adults
Dartmouth-Hitchcock Medical Center
NCT05955339
Lifestyle Interventions to Prevent Diabetes in U.S. Home Visiting Programs
California Polytechnic State University-San Luis Obispo
NCT06988306
Prolongation of GLP-1 Adherence When Using Continuous Glucose Monitoring
Abbott Diabetes Care
NCT06668935
Care Transitions App for Patients With Multiple Chronic Conditions
Brigham and Women's Hospital
NCT06051058
American Indian Chronic Renal Insufficiency Cohort Study (AI-CRIC Study)
University of New Mexi
NCT04185844
Inflammation, Diabetes, Ethnicity and Obesity Cohort
University of California, San Francisco
NCT03022682
Increasing CGM Use Among Patients With T2D
San Diego State University
NCT06638099
Cardiovascular Kidney and Metabolic Health Assessment and Patient Empowerment
Aventyn
NCT07403669
FAMily-centered WEight Loss for Black Adults (FAM WEL B-ing)
University of North Carolina, Chapel Hill
NCT06724406
Smart Walk: A Culturally Tailored Smartphone-Delivered Physical Activity Intervention for African American Women
Arizona State University
NCT06337708
Primary Care Pragmatic, Real World Experience for Automated Insulin Delivery
University of Colorado, Denver
NCT07011147
A Study to Evaluate ENERGI-F703 GEL in Diabetic Foot Ulcer
Energenesis Biomedical Co.
NCT05930210
NAUTICAL: Effect of Natriuretic Peptide Augmentation on Cardiometabolic Health in Black Individuals
University of Alabama at Birmingham
NCT04055428
ED Diabetes Screening and Outpatient Care
NYU Langone Health
NCT05899023
Behavioral Approaches to Reduce Diabetes Distress in Adults With Type 1 Diabetes: A Pragmatic SMART
University of North Carolina, Chapel Hill
NCT06405373
Radiotracer-Based Perfusion Imaging of Patients With Peripheral Arterial Disease
Nationwide Children's Hospital
NCT03622359
Clinical Trial Assessing Human Placental Membrane Products and Standard of Care Versus Standard of Care in Nonhealing DFUs and VLUs
C5 Biomedical
NCT06674980
SPYRAL GEMINI Pilot Study
Medtronic Vascular
NCT06907147
Effects of Ondansetron on Gastrointestinal Sensorimotor Dysfunctions in Diabetes Mellitus and Dyspepsia
Mayo Clinic
NCT03865290
Impact GLP-1 Agonists Following Bariatric
University of Missouri-Columbia
NCT06132477
Inpatient Use of Personal Continuous Glucose Monitor (CGM) to Improve Diabetes Mellitus Control
Mayo Clinic
NCT07006480
The Diabetes Staging System in Patient Aligned Care Teams
Durham VA Medical Center
NCT06142006
A Fruit and Vegetable Prescription Program
Milton S. Hershey Medical Center
NCT06107816
Therapeutic Plantar Electrical Stimulation Intervention During Hemodialysis to Improve Balance and Mobility
Hamad Medical Corporation
NCT05407207
Texts for Diabetes Control Among Homeless Persons
George Washington University
NCT05616026
Total Contact Soft Cast in Diabetic Foot Ulcers
University of Minnesota
NCT04210089
Repeat BCG Vaccinations for the Treatment of New Onset Type 1 Diabetes in Children Age 8-<18 Years
Massachusetts General Hospital
NCT05866536
Continuous Glucose Monitor for Mayo Clinic Advanced Care at Home Patients
Mayo Clinic
NCT05880810
A Novel Digital Tool Physicians Can Use to Prescribe Exercise to Patients With Cardiovascular Disease Risk Factors
University of Connecticut
NCT07238556
Optimizing Gait Rehabilitation for Veterans With Non-traumatic Lower Limb Amputation
VA Office of Research and Development
NCT03995238
Improving Glycemic Control With Telemedicine and Smart Insulin Pens
University of Maryland, Baltimore
NCT06918977
Full Plate Living Nutrition Education Program
University of Wisconsin, Madison
NCT07271940
Sleep, Diabetic Retinopathy and Melatonin
University of Illinois at Chicago
NCT04547439
Pioglitazone Versus Empagliflozin for Chronic Pancreatitis/Recurrent Acute Pancreatitis Associated Diabetes Mellitus
Mayo Clinic
NCT06729996
Impact of Per Oral Pyloromyotomy (POP) on Glycemic Control in Diabetes
Matthew Allemang
NCT04696159
This Study is to Evaluate Whether Receiving Education and Glucose Monitoring With the CGM Device Will Improve Patient-reported Outcomes by Improving Patient's Satisfaction and Quality of Life (QOL) With Glucose Monitoring Device
Cedars-Sinai Medical Center
NCT06965803
Dapagliflozin in Patients With Atrial Fibrillation (DAPA-AF)
University of Oklahoma
NCT05174052
Innovative Multi-Variable Biofeedback for Improving Gait Performance in Individuals With Diabetic Peripheral Neuropathy
Florida Institute for Human and Machine Cognition
NCT06591780
Diabetic Neuropathy in Spinal Cord Stimulator Patients
University of Chicago
NCT04687215
Screening and Nutrition for Patients With Diabetes: A Pilot Study
Villanova University
NCT05674110
A Study of Mesothelin-Targeted CAR T-Cell Therapy in People With Esophagogastric Cancer
Memorial Sloan Kettering Cancer Center
NCT06623396
Early Detection Initiative for Pancreatic Cancer
Pancreatic Cancer Action Network
NCT04662879
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 13 |
| Phase 2 | 19 |
| Phase 3 | 18 |
| Phase 4 | 8 |
Top Sponsors
Named interventions
Most-linked intervention names on Diabetes Mellitus records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Diabetes Mellitus trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Diabetes Mellitus page
210 registered trials, 49 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 49 Diabetes Mellitus trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Takeda sponsors the most Diabetes Mellitus trials on record, review their full trial history before evaluating a specific study. See Takeda's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Diabetes Mellitus condition card totals 210 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.