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Diabetes Mellitus clinical trials
49 of 210 indexed Diabetes Mellitus trials are currently recruiting.
210 US clinical trials · 49 currently recruiting
Diabetes Mellitus is the subject of 210 registered US clinical trials on ClinicalTrials.gov, 49 of them currently open to new participants. 26 are in Phase 3-4 (later-stage) and 32 in Phase 1-2 (earlier-stage). The most active sponsor is Takeda, running 8 of these trials.
The research picture
Diabetes Mellitus has 210 registered US clinical trials, 49 of them open to new participants right now, about 23% of the total.
- 49
- recruiting participants now
- 23%
- of trials open to enrollment
- 26
- in Phase 3–4 (later-stage)
- 8
- top sponsor: Takeda
Active & Recent Trials
210 total, page 1 of 5
Family Investigation of Nephropathy and Diabetes (F.I.N.D.)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00342927
The T1D Exchange Registry
T1D Exchange, United States
NCT04629586
Examining Digital Health Care Delivery Models Through Medicaid Collaborative
OSF Healthcare System
NCT05555095
Wolfram Syndrome and WFS1-related Disorders International Registry and Clinical Study
Washington University School of Medicine
NCT02841553
Genetics Of Autoimmunity In Type I Diabetes
Medical College of Wisconsin
NCT03648918
Rare and Atypical Diabetes Network
University of South Florida
NCT05544266
Early Tracking of Childhood Health Determinants (ETCHED) Study
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT03481829
Genetic Studies of Insulin and Diabetes
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00001987
Comparing Healthcare Visit Recording and Open Notes to Improve Chronic iLlness Care Experience in Older Adults
Dartmouth-Hitchcock Medical Center
NCT05955339
Lifestyle Interventions to Prevent Diabetes in U.S. Home Visiting Programs
California Polytechnic State University-San Luis Obispo
NCT06988306
Prolongation of GLP-1 Adherence When Using Continuous Glucose Monitoring
Abbott Diabetes Care
NCT06668935
Care Transitions App for Patients With Multiple Chronic Conditions
Brigham and Women's Hospital
NCT06051058
American Indian Chronic Renal Insufficiency Cohort Study (AI-CRIC Study)
University of New Mexi
NCT04185844
Inflammation, Diabetes, Ethnicity and Obesity Cohort
University of California, San Francisco
NCT03022682
Increasing CGM Use Among Patients With T2D
San Diego State University
NCT06638099
Cardiovascular Kidney and Metabolic Health Assessment and Patient Empowerment
Aventyn
NCT07403669
FAMily-centered WEight Loss for Black Adults (FAM WEL B-ing)
University of North Carolina, Chapel Hill
NCT06724406
Smart Walk: A Culturally Tailored Smartphone-Delivered Physical Activity Intervention for African American Women
Arizona State University
NCT06337708
Primary Care Pragmatic, Real World Experience for Automated Insulin Delivery
University of Colorado, Denver
NCT07011147
A Study to Evaluate ENERGI-F703 GEL in Diabetic Foot Ulcer
Energenesis Biomedical Co.
NCT05930210
NAUTICAL: Effect of Natriuretic Peptide Augmentation on Cardiometabolic Health in Black Individuals
University of Alabama at Birmingham
NCT04055428
ED Diabetes Screening and Outpatient Care
NYU Langone Health
NCT05899023
Behavioral Approaches to Reduce Diabetes Distress in Adults With Type 1 Diabetes: A Pragmatic SMART
University of North Carolina, Chapel Hill
NCT06405373
Radiotracer-Based Perfusion Imaging of Patients With Peripheral Arterial Disease
Nationwide Children's Hospital
NCT03622359
Clinical Trial Assessing Human Placental Membrane Products and Standard of Care Versus Standard of Care in Nonhealing DFUs and VLUs
C5 Biomedical
NCT06674980
SPYRAL GEMINI Pilot Study
Medtronic Vascular
NCT06907147
Effects of Ondansetron on Gastrointestinal Sensorimotor Dysfunctions in Diabetes Mellitus and Dyspepsia
Mayo Clinic
NCT03865290
Impact GLP-1 Agonists Following Bariatric
University of Missouri-Columbia
NCT06132477
Inpatient Use of Personal Continuous Glucose Monitor (CGM) to Improve Diabetes Mellitus Control
Mayo Clinic
NCT07006480
The Diabetes Staging System in Patient Aligned Care Teams
Durham VA Medical Center
NCT06142006
A Fruit and Vegetable Prescription Program
Milton S. Hershey Medical Center
NCT06107816
Therapeutic Plantar Electrical Stimulation Intervention During Hemodialysis to Improve Balance and Mobility
Hamad Medical Corporation
NCT05407207
Texts for Diabetes Control Among Homeless Persons
George Washington University
NCT05616026
Total Contact Soft Cast in Diabetic Foot Ulcers
University of Minnesota
NCT04210089
Repeat BCG Vaccinations for the Treatment of New Onset Type 1 Diabetes in Children Age 8-<18 Years
Massachusetts General Hospital
NCT05866536
Continuous Glucose Monitor for Mayo Clinic Advanced Care at Home Patients
Mayo Clinic
NCT05880810
A Novel Digital Tool Physicians Can Use to Prescribe Exercise to Patients With Cardiovascular Disease Risk Factors
University of Connecticut
NCT07238556
Optimizing Gait Rehabilitation for Veterans With Non-traumatic Lower Limb Amputation
VA Office of Research and Development
NCT03995238
Improving Glycemic Control With Telemedicine and Smart Insulin Pens
University of Maryland, Baltimore
NCT06918977
Full Plate Living Nutrition Education Program
University of Wisconsin, Madison
NCT07271940
Sleep, Diabetic Retinopathy and Melatonin
University of Illinois at Chicago
NCT04547439
Pioglitazone Versus Empagliflozin for Chronic Pancreatitis/Recurrent Acute Pancreatitis Associated Diabetes Mellitus
Mayo Clinic
NCT06729996
Impact of Per Oral Pyloromyotomy (POP) on Glycemic Control in Diabetes
Matthew Allemang
NCT04696159
This Study is to Evaluate Whether Receiving Education and Glucose Monitoring With the CGM Device Will Improve Patient-reported Outcomes by Improving Patient's Satisfaction and Quality of Life (QOL) With Glucose Monitoring Device
Cedars-Sinai Medical Center
NCT06965803
Dapagliflozin in Patients With Atrial Fibrillation (DAPA-AF)
University of Oklahoma
NCT05174052
Innovative Multi-Variable Biofeedback for Improving Gait Performance in Individuals With Diabetic Peripheral Neuropathy
Florida Institute for Human and Machine Cognition
NCT06591780
Diabetic Neuropathy in Spinal Cord Stimulator Patients
University of Chicago
NCT04687215
Screening and Nutrition for Patients With Diabetes: A Pilot Study
Villanova University
NCT05674110
A Study of Mesothelin-Targeted CAR T-Cell Therapy in People With Esophagogastric Cancer
Memorial Sloan Kettering Cancer Center
NCT06623396
Early Detection Initiative for Pancreatic Cancer
Pancreatic Cancer Action Network
NCT04662879
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 13 |
| Phase 2 | 19 |
| Phase 3 | 18 |
| Phase 4 | 8 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Diabetes Mellitus Trial Landscape
210 indexed Diabetes Mellitus studies · 49 recruiting (23%).
Phase mix: 26 late (III/IV) vs 32 early (I/II).
Top sponsor: Takeda (8 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Diabetes Mellitus?
PlainTrial tracks 210 US clinical trials for Diabetes Mellitus, of which 49 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Diabetes Mellitus?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.