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NCT00342927 · ClinicalTrials.gov registry record
Family Investigation of Nephropathy and Diabetes (F.I.N.D.)
A clinical trial of Diabetes Mellitus and Diabetic Kidney Disease, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
- Recruiting
- Registry status
- 100,000
- Enrollment target
- 1
- Study location
NCT00342927 is a study of Diabetes Mellitus and Diabetic Kidney Disease that is actively recruiting participants, run by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The registered enrollment target is 100,000 participants, above the 1,387-participant average among 208 other Diabetes Mellitus trials with a reported enrollment target (7110% higher). The trial reports 1 study location across 1 state.
The verdict
NCT00342927, a study of Diabetes Mellitus and Diabetic Kidney Disease, is actively recruiting participants, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
- RECRUITING
- Registry status
- 100,000 participants
- Enrollment target
- 1
- Study location
Study Summary
The Family Investigation of Nephropathy and Diabetes (FIND) is a multicenter study designed to identify genetic determinants of diabetic kidney disease. FIND will be conducted in eleven centers and in many ethnic groups throughout the United States. Two different strategies will be used to localize genes predisposing to kidney disease: a family-based genetic linkage study and a case-control study that utilizes admixture linkage disequilibrium. The center based at the Phoenix office of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK-Phoenix) will conduct family-based linkage studies among American Indian populations in the southwestern United States. Participants (index cases) with diabetes and kidney disease will initially be recruited, and their parents and siblings will also be invited to participate. Genetic material from these participants will be used to genotype markers throughout the genome. Linkage analysis will be conducted to identify particular chromosomal regions containing genes that influence susceptibility to diabetic kidney disease. Linkage analyses will also be used to identify genes influencing traits related to diabetic kidney disease, such as serum creatinine, urinary protein excretion, plasma glucose levels, blood pressure and blood lipid levels. Regions that show evidence for linkage will then be examined in more detail, with both genetic linkage and association studies, to attempt to identify the specific genes that influence diabetic kidney disease, or related traits. The identification of genes that influence susceptibility to diabetic kidney disease will lead to a better understanding of how kidney disease develops. In the long run, this may lead to improved treatment and prevention of diabetic kidney disease....
Conditions Studied
Study Locations (1)
Arizona
- NIDDK, Phoenix - Phoenix
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100,000 participants |
| Start Date | 2001-03-07 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00342927
The ClinicalTrials.gov registry entry for NCT00342927 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 100,000 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 1,387-participant average among 208 other Diabetes Mellitus trials with a reported enrollment target (7110% higher). The listed sponsor is National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which has 490 total studies on file at ClinicalTrials.gov.
The record links to 4 conditions, with Diabetes Mellitus appearing as the primary indexed condition, and to 0 interventions.
NCT00342927 reports 1 study location spanning 1 distinct geographic area - top geographies include Arizona.
Frequently Asked Questions
What is clinical trial NCT00342927 about?
NCT00342927 is a clinical study titled "Family Investigation of Nephropathy and Diabetes (F.I.N.D.)". The Family Investigation of Nephropathy and Diabetes (FIND) is a multicenter study designed to identify genetic determinants of diabetic kidney disease. FIND will be conducted in eleven centers and in many ethnic groups throughout the United States. Two different strategies will be used to localize ...
What is the current status of trial NCT00342927?
This trial is currently recruiting. The enrollment target is 100,000 participants. The study started on 2001-03-07.
What conditions does trial NCT00342927 study?
This clinical trial studies the following conditions: Diabetes Mellitus, Diabetic Kidney Disease, Diabetic Nephropathy, Albuminuria.
Who is sponsoring clinical trial NCT00342927?
This trial is sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which has 490 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00342927 being conducted?
This trial has 1 study location across Arizona. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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