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NCT00342927 · ClinicalTrials.gov registry record

Family Investigation of Nephropathy and Diabetes (F.I.N.D.)

A clinical trial of Diabetes Mellitus and Diabetic Kidney Disease, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

Recruiting
Registry status
100,000
Enrollment target
1
Study location

NCT00342927: Recruiting study of Diabetes Mellitus and Diabetic Kidney Disease, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

NCT00342927 is a study of Diabetes Mellitus and Diabetic Kidney Disease that is actively recruiting participants, run by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The registered enrollment target is 100,000 participants, above the 1,387-participant average among 208 other Diabetes Mellitus trials with a reported enrollment target (7110% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00342927, a study of Diabetes Mellitus and Diabetic Kidney Disease, is actively recruiting participants, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

RECRUITING
Registry status
100,000 participants
Enrollment target
1
Study location

Study Summary

The Family Investigation of Nephropathy and Diabetes (FIND) is a multicenter study designed to identify genetic determinants of diabetic kidney disease. FIND will be conducted in eleven centers and in many ethnic groups throughout the United States. Two different strategies will be used to localize genes predisposing to kidney disease: a family-based genetic linkage study and a case-control study that utilizes admixture linkage disequilibrium. The center based at the Phoenix office of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK-Phoenix) will conduct family-based linkage studies among American Indian populations in the southwestern United States. Participants (index cases) with diabetes and kidney disease will initially be recruited, and their parents and siblings will also be invited to participate. Genetic material from these participants will be used to genotype markers throughout the genome. Linkage analysis will be conducted to identify particular chromosomal regions containing genes that influence susceptibility to diabetic kidney disease. Linkage analyses will also be used to identify genes influencing traits related to diabetic kidney disease, such as serum creatinine, urinary protein excretion, plasma glucose levels, blood pressure and blood lipid levels. Regions that show evidence for linkage will then be examined in more detail, with both genetic linkage and association studies, to attempt to identify the specific genes that influence diabetic kidney disease, or related traits. The identification of genes that influence susceptibility to diabetic kidney disease will lead to a better understanding of how kidney disease develops. In the long run, this may lead to improved treatment and prevention of diabetic kidney disease....

Primary Outcome

Diabetes and kidney disease ascertained through diagnostic tests.

Study Locations (1)

Arizona

  • NIDDK, Phoenix - Phoenix

Trial Details

FieldValue
Enrollment Target 100,000 participants
Start Date 2001-03-07

What NCT00342927 shows while recruiting

NCT00342927 is an observational study that tracks outcomes without assigning an intervention. Its 100,000 participants enrollment target places it among the larger protocols in the corpus, above the 1,387-participant average among 208 other Diabetes Mellitus trials with a reported enrollment target (7110% higher).

The record links to 4 conditions, with Diabetes Mellitus appearing as the primary indexed condition, and to 0 interventions.

NCT00342927 reports a single indexed study location in Arizona.

Frequently Asked Questions

What is clinical trial NCT00342927 about?

NCT00342927 is a clinical study titled "Family Investigation of Nephropathy and Diabetes (F.I.N.D.)". The Family Investigation of Nephropathy and Diabetes (FIND) is a multicenter study designed to identify genetic determinants of diabetic kidney disease. FIND will be conducted in eleven centers and in many ethnic groups throughout the United States. Two different strategies will be used to localize ...

What is the current status of trial NCT00342927?

This trial is currently recruiting. The enrollment target is 100,000 participants. The study started on 2001-03-07.

What conditions does trial NCT00342927 study?

This clinical trial studies the following conditions: Diabetes Mellitus, Diabetic Kidney Disease, Diabetic Nephropathy, Albuminuria.

Who is sponsoring clinical trial NCT00342927?

This trial is sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which has 490 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00342927 being conducted?

This trial has 1 study location across Arizona. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Diabetes Mellitus

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00342927's enrollment target sits among peer trials

100,000 1st of 208 higher than 208 of 208 other Diabetes Mellitus trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Diabetes Mellitus trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00342927, the US trial registry maintained by the National Library of Medicine. NCT00342927 (large enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.