Brigham and Women's Hospital
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Brigham and Women's Hospital sits in the top decile of US sponsors by registered trial count (#35 of 15,742 sponsors by registered trial count).
Brigham and Women's Hospital: 937 sponsored US clinical trials, 145 recruiting.
Brigham and Women's Hospital sponsors 937 registered US clinical trials on ClinicalTrials.gov, 145 of them currently recruiting, and 608 completed. 124 of these trials are in Phase 3-4 (later-stage) and 197 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Type 2 Diabetes, with 13 trials.
Top-decile sponsor footprint
Brigham and Women's Hospital ranks in the top decile of sponsors by registered trial count (#35 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
608 of 677 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (89.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
937 total, page 6 of 19
Large Language Model-Generated Messages to Improve Guideline-Directed Medical Therapy in Heart Failure
NCT07337577
Combination Upper-Airway Electrical and Pharmacological Stimulation for Obstructive Sleep Apnea
NCT07577661
Transcutaneous Auricular Vagus Nerve Stimulation Treatment for Rosacea
NCT07600424
WELL-MPN: A Digital Lifestyle App for Patients With MPNs
NCT07349134
Cenobamate in the Intensive Care Unit
NCT06352723
Acute Hospital Care at Home for People Living With Dementia
NCT06819852
Evaluation of Sex Differences in Glucose Metabolism in Response to Sleep Curtailment
NCT06809023
Tirzepatide vs Semaglutide in Individuals at Cardiovascular Risk But Without Diabetes.
NCT07619508
Aromatherapy to Address Psychological Distress in Emergency Department Patients.
NCT07328412
Injectable Semaglutide vs Dulaglutide in Individuals at Cardiovascular Risk
NCT07619495
Emulation of the MONARCH-3 Trial Using Specialty Oncology Electronic Health Records Databases
NCT07225790
Use and Costs of P2Y12 Inhibitors After Acute Myocardial Infarction
NCT07610577
Comparative Effectiveness of Tirzepatide Versus Sitagliptin in Individuals at Cardiovascular Risk (TIRZSITA-CVOT)
NCT07203677
Pilot Study of Real-Time Blood Pressure Decision Support During Cesarean Delivery Under Spinal Anesthesia
NCT07534774
Effect of Music on Cue Reactivity for Patients With Opioid Use Disorder
NCT06948890
Brief Intervention for Chronic Pain and History of Stressful Experiences
NCT06983327
Emulation of the STEP-HFpEF DM Heart Failure Trial in Healthcare Claims Data
NCT06914102
Emulation of the SUMMIT Heart Failure Trial in Healthcare Claims Data
NCT06914154
Comparative Effectiveness of Tirzepatide Versus Semaglutide in Individuals With Heart Failure With Preserved Ejection Fraction
NCT06914141
Emulation of the FLAURA (NCT02296125) Trial Using Specialty Oncology Electronic Health Records Databases
NCT06675695
Emulation of the SUSTAIN6 Diabetes Trial Using Healthcare Claims
NCT06659744
Emulating the PIONEER6 Diabetes Trial Using Healthcare Claims
NCT06659679
Emulation of the SOUL Diabetes Trial in Healthcare Claims
NCT06659718
Emulation of the EMPEROR-Preserved Trial Using Healthcare Claims Data
NCT07599293
Emulation of the RECORD3 Trial Using Healthcare Claims Data
NCT07599384
Emulation of the EMPEROR-Reduced Trial Using Healthcare Claims Data
NCT07599345
Comparative Effectiveness of Tirzepatide and Semaglutide in Individuals at Cardiovascular Risk
NCT07096063
Prediction of the SURPASS-CVOT Cardiovascular Outcome Trial in Healthcare Claims Data
NCT07088718
Biomarkers of AKI in Patients Receiving Daratumumab
NCT06549634
A Single-Dose, Three-Way, Three-Sequence, Crossover BA Study of Azithromycin Oleogel
NCT05796362
Deprescribing in Patients Living With Dementia With Caregiver and Provider Nudges
NCT06347172
Dexmedetomidine Infusion and Postoperative Lung Aeration After Thoracic Surgery
NCT06502002
Connectomic Targeted TMS Target for Refractory Anxiety
NCT06376877
Ketamine for OUD and Suicidal Ideation in the ED
NCT06111339
Oral Buprenorphine as a Novel Low-dose Induction Strategy for Opioid Use Disorder
NCT06086275
Mindfulness Intervention for Fibromyalgia Delivered Through a Smartphone App
NCT07032519
Anti-Platelets in Chronic Obstructive Pulmonary Disease
NCT05567562
Peer Support Intervention for Patients Undergoing Hematopoietic Stem Cell Transplantation
NCT06010017
Multimodal, Task-Aware Movement Assessment and Control Using Functional Electrical Stimulation
NCT06301542
Emergency Care at Home
NCT06299774
Adjunctive Mindfulness During Opioid Tapering for patientS With Chronic Pain (The AMOS Study)
NCT06268522
Smart Phone Delivered Cognitive Behavioral Therapy for Adults With Psoriasis and Co-Morbid Depression Symptoms
NCT06216691
Pharyngeal Muscle Control Mechanisms of Atomoxetine-plus-oxybutynin in Obstructive Sleep Apnea
NCT05944965
Long-term Effects of Blueberry Supplementation on Brain Health in Older Adults
NCT05764824
AGE SELF CARE: Promoting Healthy Aging Through a Group Visit Program
NCT06079762
The Effects of Tasimelteon in Participants With REM Behavior Disorder (RBD)
NCT05922995
Understanding Rebound Pain After Regional Anesthesia Resolution in Healthy Volunteers
NCT06005480
Refinement and Adaption of Reinforcement Learning to Personalize Behavioral Messaging for Healthy Habits
NCT05742685
Social Norms, Messengers, and Processing Fluency to Increase Hypertension Medication Adherence
NCT06066541
Deucravacitinib for the Treatment of Palmoplantar Pustulosis
NCT05710185
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 90 |
| Phase 2 | 107 |
| Phase 3 | 47 |
| Phase 4 | 77 |
Therapeutic Areas
What is open in the Brigham and Women's Hospital pipeline
145 recruiting of 937 indexed (15% open); 608 completed (65%).
Phase mix: 124 late (III/IV) vs 197 early (I/II) (early-phase heavy).
Top condition: Type 2 Diabetes (13 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Brigham and Women's Hospital: open-pipeline peers nationwide
Peers matched on 937 registered trials and 15% open enrollment, not the therapeutic-area sidebar.
Brigham and Women's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 937 trials (± recruiting share)
- Columbia University · 958 trials · 18% recruiting
- Hoffmann-La Roche · 909 trials · 8% recruiting
- University of Minnesota · 966 trials · 19% recruiting
- University of California, Los Angeles · 897 trials · 18% recruiting
Sponsors near 15% open enrollment (± trial volume)
- Incyte Corporation · 15% recruiting · 239 trials
- Northwestern University · 15% recruiting · 1,209 trials
- Nationwide Children's Hospital · 15% recruiting · 188 trials
- University of Michigan Rogel Cancer Center · 15% recruiting · 292 trials
Related
What to do with this Brigham and Women's Hospital page
937 registered trials is a research-attention snapshot, not an endorsement of Brigham and Women's Hospital or any single study.
- 145 of Brigham and Women's Hospital's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Type 2 Diabetes is the condition Brigham and Women's Hospital studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Type 2 Diabetes trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Brigham and Women's Hospital pipeline card: 937 registered trials from official public datasets.Report a data error.