Brigham and Women's Hospital

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Brigham and Women's Hospital sits in the top decile of US sponsors by registered trial count (#35 of 15,742 sponsors by registered trial count).

937 total trials 145 currently recruiting 608 completed early-phase tilt top decile by trial count

Brigham and Women's Hospital: 937 sponsored US clinical trials, 145 recruiting.

Brigham and Women's Hospital sponsors 937 registered US clinical trials on ClinicalTrials.gov, 145 of them currently recruiting, and 608 completed. 124 of these trials are in Phase 3-4 (later-stage) and 197 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Type 2 Diabetes, with 13 trials.

Top-decile sponsor footprint

Brigham and Women's Hospital ranks in the top decile of sponsors by registered trial count (#35 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 64/100

608 of 677 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (89.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

937 total, page 7 of 19

COMPLETED NA

SCI-Lynx: A Mobile Platform for Physical Activity Social Support for People With SCI Pilot Study

NCT05764135

COMPLETED NA

Electronic Strategies for Tailored Exercise to Prevent FallS

NCT04993781

COMPLETED Phase 4

COPILOT-HF: Cooperative Program for ImpLementation of Optimal Therapy in Heart Failure

NCT05734690

COMPLETED NA

Addressing Diffusion of Responsibility and Prescribing Burden to Improve Use of Diabetes Medications

NCT05463705

COMPLETED NA

MED3000 Topical Gel for On-Demand Treatment of Post-Radical Prostatectomy Erectile Dysfunction

NCT05673005

COMPLETED NA

The Effects of a Virtual Yoga Program on Patients With Chronic Pain

NCT05211414

COMPLETED NA

Project 1: Self-Triage by 2D Full-field Digital Mammography or Synthetic Images

NCT05960188

NOT YET RECRUITING NA

Achieving Diagnostic Excellence Through Prevention and Teamwork

NCT05747755

COMPLETED Phase 3

Next Generation Ingestible Sensors for Medication Adherence Measurement

NCT05592613

COMPLETED Phase 1

Acetazolamide on REM OSA

NCT05589792

COMPLETED Phase 1

A Study on Hydroxocobalamin Given to Healthy Individual to Monitor Symptoms

NCT07469189

NOT YET RECRUITING NA

Three-dimensional (3D) Printed Hemodialysis Vascular Model

NCT05096416

COMPLETED NA

Implementation of Whole Genome Sequencing as Screening in a Diverse Cohort of Healthy Infants

NCT05161169

COMPLETED NA

Decision Support for Detection of Chronic Kidney Disease in Type II Diabetes Mellitus

NCT05342545

COMPLETED

Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Propranolol/Carvedilol Versus Atenolol/Bisoprolol/Sotalol

NCT05794997

COMPLETED

Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Semaglutide v DPP4 Inhibitors

NCT05768945

COMPLETED NA

NUDGE-EHR Replication Trial at Mass General Brigham

NCT05538065

TERMINATED Phase 4

Study on Allopregnanolone and Depression in Perimenopausal Women

NCT05329779

COMPLETED NA

A Behavioral Science-Enhanced PHysician-led Remote Group Exercise InTervention for Women With Coronary Artery Disease

NCT05611333

COMPLETED

Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Anastrozole vs Exemestane/Letrozole

NCT05635357

COMPLETED

Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Pentoxifylline Versus Cilostazol

NCT05635370

COMPLETED Early Phase 1

Endocannabinoids, Stress, Craving And Pain Effects Study

NCT05480072

COMPLETED Early Phase 1

Personalizing Preprocedural Sedation for Regional Anesthesia

NCT05579509

COMPLETED

Evaluation of the Impact of a Forward Viewing Scope at Time of ERCP

NCT05627882

COMPLETED NA

Efficacy of the Quell Wearable Device for Chronic Overlapping Pain Conditions

NCT05540002

COMPLETED NA

Design and Usability Testing of a Tailored Intervention About Sleep and Sleep Disorders Among Transportation Workers

NCT05039528

COMPLETED

Role of IL-5R Signaling in Non-eosinophil Upper Airway Cells in CRSwNP

NCT05672030

COMPLETED NA

Self-Directed Positive Psychology Intervention for Newly Diagnosed Multiple Sclerosis

NCT06891937

COMPLETED NA

Decreasing Unnecessary Antibiotics Prescribed for Possible Pneumonia Despite Normal Respiratory Rate and Oxygenation

NCT05172791

COMPLETED NA

Toward Understanding Drivers of Patient Engagement With Digital Mental Health Interventions - Part I

NCT05360901

COMPLETED Phase 1

Digital Fall Prevention Study

NCT05432674

COMPLETED NA

Breaking Implicit Bias Habits: An Individuation Pilot Study In Rheumatology

NCT05116163

TERMINATED NA

TEAMS-BP (The Enhancement of Social Networks to Augment Management of Stroke-Blood Pressure)

NCT05258890

COMPLETED NA

Leveraging Electronic Health Record (EHR) Tools to Reduce Health Disparities for Patients With Uncontrolled Hypertension

NCT05030467

COMPLETED NA

Cook Balloon vs Dilapan-S for Outpatient Cervical Ripening

NCT05062343

COMPLETED Phase 2

Cannabidiol on Reward- and Stress-related Neurocognitive Processes in Individuals With Opioid Use Disorder

NCT04982029

TERMINATED

Observational Study of the Effect of Ozanimod on Fatigue in Multiple Sclerosis Patients

NCT05319093

COMPLETED NA

Influence of Nocturnal Light Exposure on the Impairment of Glucose Tolerance Induced by Chronic Sleep Restriction

NCT04868539

COMPLETED NA

Proof-of-Concept Trial of a Positive Psychology Intervention for Caregivers of Patients Undergoing HSCT

NCT05216978

COMPLETED NA

Advance Care Planning in the Emergency Department

NCT05209880

COMPLETED NA

Home Hospital for Bariatric Sleeve Gastrectomy

NCT05259111

COMPLETED NA

Use of Construal Level Theory to Inform Messaging to Increase Vaccination Against COVID-19

NCT04871776

COMPLETED NA

Rural Hospital-Level Care at Home for Acutely Ill Adults

NCT05256303

COMPLETED NA

Sleep Well: Digital Insomnia Treatment Program For Physicians

NCT05289596

COMPLETED

Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - Montelukast vs Fluticasone

NCT05457855

COMPLETED NA

The Effect of Mouth Closure on Airflow in OSA

NCT06547658

COMPLETED

Ocrelizumab Access by Socio-Economic Status

NCT05131984

COMPLETED Phase 1

Nasal Protollin in Early Symptomatic Alzheimer's Disease

NCT07187141

COMPLETED NA

Positive Psychology Intervention In HSCT

NCT05147311

COMPLETED

Validation of Circadian Biomarkers in Patients With Sleep Disorders

NCT04690504

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Phase Distribution

PhaseTrial count
Phase 1 90
Phase 2 107
Phase 3 47
Phase 4 77

What is open in the Brigham and Women's Hospital pipeline

145 recruiting of 937 indexed (15% open); 608 completed (65%).

Phase mix: 124 late (III/IV) vs 197 early (I/II) (early-phase heavy).

Top condition: Type 2 Diabetes (13 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Brigham and Women's Hospital: open-pipeline peers nationwide

Peers matched on 937 registered trials and 15% open enrollment, not the therapeutic-area sidebar.

Brigham and Women's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 5%10%15%20% Total trials Recruiting share Brigham and Women's HospitalColumbia UniversityHoffmann-La RocheUniversity of MinnesotaUniversity of California, Los AngelesIncyte CorporationNorthwestern UniversityNationwide Children's HospitalUniversity of Michigan Rogel Cancer Center
Brigham and Women's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Brigham and Women's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 937 trials (± recruiting share)

Sponsors near 15% open enrollment (± trial volume)

What to do with this Brigham and Women's Hospital page

937 registered trials is a research-attention snapshot, not an endorsement of Brigham and Women's Hospital or any single study.

  • 145 of Brigham and Women's Hospital's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Type 2 Diabetes is the condition Brigham and Women's Hospital studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Type 2 Diabetes trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Brigham and Women's Hospital pipeline card: 937 registered trials from official public datasets.Report a data error.