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NCT07225790 · ClinicalTrials.gov registry record
Emulation of the MONARCH-3 Trial Using Specialty Oncology Electronic Health Records Databases
A clinical trial, sponsored by Brigham and Women's Hospital.
- Completed
- Registry status
- 3,883
- Enrollment target
NCT07225790: Completed study, sponsored by Brigham and Women's Hospital.
NCT07225790 is a clinical trial that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 3,883 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07225790 has completed, sponsored by Brigham and Women's Hospital.
- COMPLETED
- Registry status
- 3,883 participants
- Enrollment target
Study Summary
Investigators are building an empirical evidence base for real world data through large-scale emulation of randomized controlled trials. The investigators' goal is to understand for what types of clinical questions real world data analyses can be conducted with confidence and how to implement such studies.
Primary Outcome
Hazard ratio (95% CI)
Interventions
- DRUG Initiation of abemaciclib plus letrozole/anastrozole
- DRUG Initiation of letrozole/anastrozole
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3,883 participants |
| Start Date | 2025-11-03 |
| Est. Completion | 2026-01-31 |
What the finished NCT07225790 record still lists
NCT07225790 is an observational study that tracks outcomes without assigning an intervention. Its 3,883 participants enrollment target places it among the larger protocols in the corpus.
The record links to 0 conditions, and to 2 interventions - of which Initiation of abemaciclib plus letrozole/anastrozole is the first listed.
NCT07225790 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07225790 about?
NCT07225790 is a clinical study titled "Emulation of the MONARCH-3 Trial Using Specialty Oncology Electronic Health Records Databases". Investigators are building an empirical evidence base for real world data through large-scale emulation of randomized controlled trials. The investigators' goal is to understand for what types of clinical questions real world data analyses can be conducted with confidence and how to implement such s...
What is the current status of trial NCT07225790?
This trial is currently completed. The enrollment target is 3,883 participants. The study started on 2025-11-03. Estimated completion is 2026-01-31.
What interventions are being tested in trial NCT07225790?
The interventions under investigation include: Initiation of abemaciclib plus letrozole/anastrozole (DRUG), Initiation of letrozole/anastrozole (DRUG).
Who is sponsoring clinical trial NCT07225790?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
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