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NCT07225790 · ClinicalTrials.gov registry record

Emulation of the MONARCH-3 Trial Using Specialty Oncology Electronic Health Records Databases

A clinical trial, sponsored by Brigham and Women's Hospital.

Completed
Registry status
3,883
Enrollment target

NCT07225790 is a clinical trial that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 3,883 participants.

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The verdict

NCT07225790 has completed, sponsored by Brigham and Women's Hospital.

COMPLETED
Registry status
3,883 participants
Enrollment target

Study Summary

Investigators are building an empirical evidence base for real world data through large-scale emulation of randomized controlled trials. The investigators' goal is to understand for what types of clinical questions real world data analyses can be conducted with confidence and how to implement such studies.

Interventions

  • DRUG Initiation of abemaciclib plus letrozole/anastrozole
  • DRUG Initiation of letrozole/anastrozole

Trial Details

FieldValue
Enrollment Target 3,883 participants
Start Date 2025-11-03
Est. Completion 2026-01-31

Sponsor

Brigham and Women's Hospital

937 total trials

What the Registry Record Tells You About NCT07225790

The ClinicalTrials.gov registry entry for NCT07225790 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 3,883 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Brigham and Women's Hospital, which has 937 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Initiation of abemaciclib plus letrozole/anastrozole is the first listed.

NCT07225790 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT07225790 about?

NCT07225790 is a clinical study titled "Emulation of the MONARCH-3 Trial Using Specialty Oncology Electronic Health Records Databases". Investigators are building an empirical evidence base for real world data through large-scale emulation of randomized controlled trials. The investigators' goal is to understand for what types of clinical questions real world data analyses can be conducted with confidence and how to implement such s...

What is the current status of trial NCT07225790?

This trial is currently completed. The enrollment target is 3,883 participants. The study started on 2025-11-03. Estimated completion is 2026-01-31.

What interventions are being tested in trial NCT07225790?

The interventions under investigation include: Initiation of abemaciclib plus letrozole/anastrozole (DRUG), Initiation of letrozole/anastrozole (DRUG).

Who is sponsoring clinical trial NCT07225790?

This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.