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NCT06659679 · ClinicalTrials.gov registry record
Emulating the PIONEER6 Diabetes Trial Using Healthcare Claims
A clinical trial of Diabetes Mellitus, Type 2, sponsored by Brigham and Women's Hospital.
- Completed
- Registry status
- 26,126
- Enrollment target
- 1
- Study location
NCT06659679: Completed study of Diabetes Mellitus, Type 2, sponsored by Brigham and Women's Hospital.
NCT06659679 is a study of Diabetes Mellitus, Type 2 that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 26,126 participants, above the 4,410-participant average among 348 other Diabetes Mellitus, Type 2 trials with a reported enrollment target (492% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06659679, a study of Diabetes Mellitus, Type 2, has completed, sponsored by Brigham and Women's Hospital.
- COMPLETED
- Registry status
- 26,126 participants
- Enrollment target
- 1
- Study location
Study Summary
Investigators are building an empirical evidence base for real world data through large-scale emulation of randomized controlled trials. The investigators' goal is to understand for what types of clinical questions real world data analyses can be conducted with confidence and how to implement such studies.
Primary Outcome
Hazard ratio
Conditions Studied
Interventions
- DRUG New initiation of sitagliptin
- DRUG New use of oral semaglutide
Study Locations (1)
Massachusetts
- Brigham and Women's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 26,126 participants |
| Start Date | 2024-10-24 |
| Est. Completion | 2025-03-06 |
What the finished NCT06659679 record still lists
NCT06659679 is an observational study that tracks outcomes without assigning an intervention. Its 26,126 participants enrollment target places it among the larger protocols in the corpus, above the 4,410-participant average among 348 other Diabetes Mellitus, Type 2 trials with a reported enrollment target (492% higher).
The record links to 1 condition, with Diabetes Mellitus, Type 2 appearing as the primary indexed condition, and to 2 interventions - of which New initiation of sitagliptin is the first listed.
NCT06659679 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT06659679 about?
NCT06659679 is a clinical study titled "Emulating the PIONEER6 Diabetes Trial Using Healthcare Claims". Investigators are building an empirical evidence base for real world data through large-scale emulation of randomized controlled trials. The investigators' goal is to understand for what types of clinical questions real world data analyses can be conducted with confidence and how to implement such s...
What is the current status of trial NCT06659679?
This trial is currently completed. The enrollment target is 26,126 participants. The study started on 2024-10-24. Estimated completion is 2025-03-06.
What conditions does trial NCT06659679 study?
This clinical trial studies the following conditions: Diabetes Mellitus, Type 2.
What interventions are being tested in trial NCT06659679?
The interventions under investigation include: New initiation of sitagliptin (DRUG), New use of oral semaglutide (DRUG).
Who is sponsoring clinical trial NCT06659679?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06659679 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Diabetes Mellitus, Type 2
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06659679's enrollment target sits among peer trials
26,126 7th of 348 higher than 342 of 348 other Diabetes Mellitus, Type 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Diabetes Mellitus, Type 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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